Results 61 to 70 of about 1,155,632 (287)

Redesigning metabolism based on orthogonality principles [PDF]

open access: yesNature Communications, 2017
AbstractModifications made during metabolic engineering for overproduction of chemicals have network-wide effects on cellular function due to ubiquitous metabolic interactions. These interactions, that make metabolic network structures robust and optimized for cell growth, act to constrain the capability of the cell factory.
Aditya Vikram Pandit   +2 more
openaire   +3 more sources

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

open access: yesFEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source

Using the software package of approximate correlated-spectral analysis for data processing problems solving

open access: yesVestnik Samarskogo Gosudarstvennogo Tehničeskogo Universiteta. Seriâ: Fiziko-Matematičeskie Nauki, 2007
We describe the problems solved by the software package of correlated-spectral analysis, which allows analyzing the random processes in Legendre, Laguerre and Dirichlet orthogonal bases.
S. A. Prokhorov, A. V. Grafkin
doaj   +1 more source

On the Orthogonal Bases of Symmetry Classes

open access: yesJournal of Algebra, 1999
Let \(V\) be an \(n\)-dimensional complex inner product space and let \(\{e_1,\dots,e_n\}\) be an orthonormal basis of \(V\). Suppose \(G\) is a permutation group of degree \(m\) and \(X\) is an irreducible character of \(G\). The symmetry class of tensors associated with \(G\) and \(X\) is denoted by \(V_X(G)\).
openaire   +1 more source

Orthogonal bases are Schauder bases and a characterization of Φ-algebras [PDF]

open access: yesPacific Journal of Mathematics, 1988
Soit A une algèbre topologique. Une base \((e_ n)\) de A, considéré comme espace vectoriel topologique, est dite orthogonale lorsque \(e_ m\cdot e_ n=\delta_{mn}e_ n\) \((\delta_{mn}\) \(=\) symbole de Kronecker). On montre que toute base orthogonale d'une algèbre topologique est de Schauder, c'est-à-dire les formes linéaires associées sont continues ...
El-Helaly, Sherif, Husain, Taqdir
openaire   +2 more sources

Orthogonal unitary bases and a subfactor conjecture

open access: yesProceedings of the American Mathematical Society, 2023
We show that any finite dimensional von Neumann algebra admits an orthonormal unitary basis with respect to its standard trace. We also show that a finite dimensional von Neumann subalgebra of
Crann, Jason   +2 more
openaire   +2 more sources

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

open access: yesFEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill   +4 more
wiley   +1 more source

On base change for odd orthogonal groups [PDF]

open access: yesJournal of the American Mathematical Society, 1995
Let \(G\) be an orthogonal group over \(\mathbb{Q}\) with \(G(\mathbb{R}) \cong \text{SO} (2n, 1)\). The main purpose of this paper is to show that the most obvious idea of a base change map for such groups does not exist. More precisely they show that there is a cuspidal automorphic representation \(\pi\) for \(G\) and a real quadratic extension \(K\)
Cogdell, J. W.   +1 more
openaire   +2 more sources

Directed evolution of enzymes at the crossroads of tradition and innovation

open access: yesFEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova   +2 more
wiley   +1 more source

Dose‐dependent hepatotoxicity of hydrogen peroxide in HepG2 cells and its modulation by CYP450 induction

open access: yesFEBS Open Bio, EarlyView.
NMR metabolomics revealed concentration‐dependent metabolic perturbations in HepG2 cells exposed to H2O2. Rifampicin pretreatment enhanced metabolic competence, attenuated toxin‐induced alterations and produced metabolite profiles more consistent with human liver physiology, supporting the use of CYP450‐induced HepG2 models for improved in vitro ...
Maren Jinks   +4 more
wiley   +1 more source

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