Results 51 to 60 of about 21,325 (267)

The impact of leukocyte‐associated RNA retention on platelet RNA‐based cancer detection

open access: yesMolecular Oncology, EarlyView.
Platelets carry RNA signals that may help detect cancer, but platelet samples can also retain RNA from white blood cells. We found that this retained white blood cell signal did not significantly affect machine learning cancer classification, suggesting that the cancer‐related RNA signal in platelets is largely independent of leukocyte‐associated RNA ...
Michał Sieczczyński   +12 more
wiley   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

open access: yesFEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova   +2 more
wiley   +1 more source

Using the software package of approximate correlated-spectral analysis for data processing problems solving

open access: yesVestnik Samarskogo Gosudarstvennogo Tehničeskogo Universiteta. Seriâ: Fiziko-Matematičeskie Nauki, 2007
We describe the problems solved by the software package of correlated-spectral analysis, which allows analyzing the random processes in Legendre, Laguerre and Dirichlet orthogonal bases.
S. A. Prokhorov, A. V. Grafkin
doaj   +1 more source

On the Orthogonal Bases of Symmetry Classes

open access: yesJournal of Algebra, 1999
Let \(V\) be an \(n\)-dimensional complex inner product space and let \(\{e_1,\dots,e_n\}\) be an orthonormal basis of \(V\). Suppose \(G\) is a permutation group of degree \(m\) and \(X\) is an irreducible character of \(G\). The symmetry class of tensors associated with \(G\) and \(X\) is denoted by \(V_X(G)\).
openaire   +1 more source

On base change for odd orthogonal groups [PDF]

open access: yesJournal of the American Mathematical Society, 1995
Let \(G\) be an orthogonal group over \(\mathbb{Q}\) with \(G(\mathbb{R}) \cong \text{SO} (2n, 1)\). The main purpose of this paper is to show that the most obvious idea of a base change map for such groups does not exist. More precisely they show that there is a cuspidal automorphic representation \(\pi\) for \(G\) and a real quadratic extension \(K\)
Cogdell, J. W.   +1 more
openaire   +2 more sources

Orthogonal unitary bases and a subfactor conjecture

open access: yesProceedings of the American Mathematical Society, 2023
We show that any finite dimensional von Neumann algebra admits an orthonormal unitary basis with respect to its standard trace. We also show that a finite dimensional von Neumann subalgebra of
Crann, Jason   +2 more
openaire   +2 more sources

Dose‐dependent hepatotoxicity of hydrogen peroxide in HepG2 cells and its modulation by CYP450 induction

open access: yesFEBS Open Bio, EarlyView.
NMR metabolomics revealed concentration‐dependent metabolic perturbations in HepG2 cells exposed to H2O2. Rifampicin pretreatment enhanced metabolic competence, attenuated toxin‐induced alterations and produced metabolite profiles more consistent with human liver physiology, supporting the use of CYP450‐induced HepG2 models for improved in vitro ...
Maren Jinks   +4 more
wiley   +1 more source

Orthogonal bases are Schauder bases and a characterization of Φ-algebras [PDF]

open access: yesPacific Journal of Mathematics, 1988
Soit A une algèbre topologique. Une base \((e_ n)\) de A, considéré comme espace vectoriel topologique, est dite orthogonale lorsque \(e_ m\cdot e_ n=\delta_{mn}e_ n\) \((\delta_{mn}\) \(=\) symbole de Kronecker). On montre que toute base orthogonale d'une algèbre topologique est de Schauder, c'est-à-dire les formes linéaires associées sont continues ...
El-Helaly, Sherif, Husain, Taqdir
openaire   +2 more sources

Accurate and noninvasive prostate cancer detection using plasma‐derived extracellular vesicle RNA

open access: yesFEBS Open Bio, EarlyView.
Plasma extracellular vesicles were captured with WGA‐conjugated magnetic beads and profiled for RNA biomarkers. A three‐RNA panel (NM_024955, NR_047469, and NR_002564) distinguished prostate cancer from healthy controls and benign prostatic hyperplasia, supporting a simple, noninvasive approach to improve prostate cancer detection.
Hanping Wei, Haoran Wu, Wei Feng
wiley   +1 more source

BCG vaccination potentiates oxidative phosphorylation in neonatal myeloid‐derived suppressor cells

open access: yesFEBS Open Bio, EarlyView.
BCG vaccination enhances oxidative phosphorylation in neonatal MDSCs, impairing their immunosuppressive function. It upregulates electron transport chain genes and mitochondrial activity, increasing ATP and oxygen consumption. Pharmacological OXPHOS inhibition partially restores suppressive capacity, confirming causality.
Yingying Chen, Hui Li
wiley   +1 more source

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