Results 51 to 60 of about 21,325 (267)
The impact of leukocyte‐associated RNA retention on platelet RNA‐based cancer detection
Platelets carry RNA signals that may help detect cancer, but platelet samples can also retain RNA from white blood cells. We found that this retained white blood cell signal did not significantly affect machine learning cancer classification, suggesting that the cancer‐related RNA signal in platelets is largely independent of leukocyte‐associated RNA ...
Michał Sieczczyński +12 more
wiley +1 more source
Directed evolution of enzymes at the crossroads of tradition and innovation
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova +2 more
wiley +1 more source
We describe the problems solved by the software package of correlated-spectral analysis, which allows analyzing the random processes in Legendre, Laguerre and Dirichlet orthogonal bases.
S. A. Prokhorov, A. V. Grafkin
doaj +1 more source
On the Orthogonal Bases of Symmetry Classes
Let \(V\) be an \(n\)-dimensional complex inner product space and let \(\{e_1,\dots,e_n\}\) be an orthonormal basis of \(V\). Suppose \(G\) is a permutation group of degree \(m\) and \(X\) is an irreducible character of \(G\). The symmetry class of tensors associated with \(G\) and \(X\) is denoted by \(V_X(G)\).
openaire +1 more source
On base change for odd orthogonal groups [PDF]
Let \(G\) be an orthogonal group over \(\mathbb{Q}\) with \(G(\mathbb{R}) \cong \text{SO} (2n, 1)\). The main purpose of this paper is to show that the most obvious idea of a base change map for such groups does not exist. More precisely they show that there is a cuspidal automorphic representation \(\pi\) for \(G\) and a real quadratic extension \(K\)
Cogdell, J. W. +1 more
openaire +2 more sources
Orthogonal unitary bases and a subfactor conjecture
We show that any finite dimensional von Neumann algebra admits an orthonormal unitary basis with respect to its standard trace. We also show that a finite dimensional von Neumann subalgebra of
Crann, Jason +2 more
openaire +2 more sources
NMR metabolomics revealed concentration‐dependent metabolic perturbations in HepG2 cells exposed to H2O2. Rifampicin pretreatment enhanced metabolic competence, attenuated toxin‐induced alterations and produced metabolite profiles more consistent with human liver physiology, supporting the use of CYP450‐induced HepG2 models for improved in vitro ...
Maren Jinks +4 more
wiley +1 more source
Orthogonal bases are Schauder bases and a characterization of Φ-algebras [PDF]
Soit A une algèbre topologique. Une base \((e_ n)\) de A, considéré comme espace vectoriel topologique, est dite orthogonale lorsque \(e_ m\cdot e_ n=\delta_{mn}e_ n\) \((\delta_{mn}\) \(=\) symbole de Kronecker). On montre que toute base orthogonale d'une algèbre topologique est de Schauder, c'est-à-dire les formes linéaires associées sont continues ...
El-Helaly, Sherif, Husain, Taqdir
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Accurate and noninvasive prostate cancer detection using plasma‐derived extracellular vesicle RNA
Plasma extracellular vesicles were captured with WGA‐conjugated magnetic beads and profiled for RNA biomarkers. A three‐RNA panel (NM_024955, NR_047469, and NR_002564) distinguished prostate cancer from healthy controls and benign prostatic hyperplasia, supporting a simple, noninvasive approach to improve prostate cancer detection.
Hanping Wei, Haoran Wu, Wei Feng
wiley +1 more source
BCG vaccination potentiates oxidative phosphorylation in neonatal myeloid‐derived suppressor cells
BCG vaccination enhances oxidative phosphorylation in neonatal MDSCs, impairing their immunosuppressive function. It upregulates electron transport chain genes and mitochondrial activity, increasing ATP and oxygen consumption. Pharmacological OXPHOS inhibition partially restores suppressive capacity, confirming causality.
Yingying Chen, Hui Li
wiley +1 more source

