Results 51 to 60 of about 1,155,632 (287)

Quasimodules over bounded lattices [PDF]

open access: yesMathematica Bohemica
We define a quasimodule $ Q$ over a bounded lattice $\bf L$ in an analogous way as a module over a semiring is defined. The essential difference is that $\bf L$ need not be distributive.
Ivan Chajda, Helmut Länger
doaj   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

open access: yesFEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri   +5 more
wiley   +1 more source

Existence and Construction of Tangential and Anisotropic Bases in Finite-Dimensional Quadratic Spaces

open access: yesMathematics
This paper studies the existence and construction of bases consisting of tangential and anisotropic vectors in finite-dimensional quadratic spaces over fields of characteristic different from two.
Alexander Leones   +3 more
doaj   +1 more source

On orthogonal p-adic wavelet bases

open access: yesJournal of Mathematical Analysis and Applications, 2015
A variety of different orthogonal wavelet bases has been found in L_2(R) for the last three decades. It appeared that similar constructions also exist for functions defined on some other algebraic structures, such as the Cantor and Vilenkin groups and local fields of positive characteristic.
Evdokimov, S., Skopina, M.
openaire   +3 more sources

Invisible but not inaccessible—Revealing transient oligomers formed by intrinsically disordered proteins with solution NMR and complementary methods

open access: yesFEBS Letters, EarlyView.
Transient oligomers formed by intrinsically disordered proteins may be ‘invisible’ to direct detection yet remain accessible to solution NMR through equilibrium‐exchange measurements and pressure‐jump experiments. Complementary methods report on mass, stoichiometry, selected distance distributions, morphology, and internal packing.
Martin D. Gelenter, Ad Bax
wiley   +1 more source

Topological Algebras with Orthogonal M-bases [PDF]

open access: yes, 1985
An M-basis in a topological vector space is a special case of the extended Markushevich basis, and a generalization of the unconditional basis. We study orthogonal bases and orthogonal M-bases in topological algebras, with emphasis on locally convex ...
El-Helaly, Taha Sherif
core   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

Orthogonal least squares regression with tunable kernels [PDF]

open access: yes, 2005
A novel technique is proposed to construct sparse regression models based on the orthogonal least squares method with tunable kernels. The proposed technique tunes the centre vector and diagonal covariance matrix of individual regressor by incrementally ...
Wang, X. X.   +4 more
core   +2 more sources

Optimal control design for linear - invariant linear singular systems with time using orthogonal functions [PDF]

open access: yesتصمیم گیری و تحقیق در عملیات, 2019
The problem of solving optimal control of Singular problems in the classic method has a complexity that is solved by approximation of the equations in the problem with orthogonal bases instead of solving the dynamic equation system of a set of static ...
Hamid Tabatabaee, Mahdi Memari
doaj   +1 more source

Spatial biology in cancer epigenetics

open access: yesMolecular Oncology, EarlyView.
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley   +1 more source

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