Results 51 to 60 of about 1,155,632 (287)
Quasimodules over bounded lattices [PDF]
We define a quasimodule $ Q$ over a bounded lattice $\bf L$ in an analogous way as a module over a semiring is defined. The essential difference is that $\bf L$ need not be distributive.
Ivan Chajda, Helmut Länger
doaj +1 more source
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
This paper studies the existence and construction of bases consisting of tangential and anisotropic vectors in finite-dimensional quadratic spaces over fields of characteristic different from two.
Alexander Leones +3 more
doaj +1 more source
On orthogonal p-adic wavelet bases
A variety of different orthogonal wavelet bases has been found in L_2(R) for the last three decades. It appeared that similar constructions also exist for functions defined on some other algebraic structures, such as the Cantor and Vilenkin groups and local fields of positive characteristic.
Evdokimov, S., Skopina, M.
openaire +3 more sources
Transient oligomers formed by intrinsically disordered proteins may be ‘invisible’ to direct detection yet remain accessible to solution NMR through equilibrium‐exchange measurements and pressure‐jump experiments. Complementary methods report on mass, stoichiometry, selected distance distributions, morphology, and internal packing.
Martin D. Gelenter, Ad Bax
wiley +1 more source
Topological Algebras with Orthogonal M-bases [PDF]
An M-basis in a topological vector space is a special case of the extended Markushevich basis, and a generalization of the unconditional basis. We study orthogonal bases and orthogonal M-bases in topological algebras, with emphasis on locally convex ...
El-Helaly, Taha Sherif
core +1 more source
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
Orthogonal least squares regression with tunable kernels [PDF]
A novel technique is proposed to construct sparse regression models based on the orthogonal least squares method with tunable kernels. The proposed technique tunes the centre vector and diagonal covariance matrix of individual regressor by incrementally ...
Wang, X. X. +4 more
core +2 more sources
Optimal control design for linear - invariant linear singular systems with time using orthogonal functions [PDF]
The problem of solving optimal control of Singular problems in the classic method has a complexity that is solved by approximation of the equations in the problem with orthogonal bases instead of solving the dynamic equation system of a set of static ...
Hamid Tabatabaee, Mahdi Memari
doaj +1 more source
Spatial biology in cancer epigenetics
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley +1 more source

