Results 41 to 50 of about 161,308 (277)
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
Towards polarisation-encoded quantum key distribution in optical fibre networks
South African Journal of Science, 2015 Quantum key distribution – a process that encodes digital information – often utilises fibre optic technologies for commercial applications. Fibre provides the benefit of a dark channel as well as the convenience of independence of a line-of-sight ...
Sharmini Pillay +2 more
doaj +1 more source
Duality Preserving Gray Maps for Codes over Rings
, 2016 Given a finite ring $A$ which is a free left module over a subring $R$ of $A$, two types of $R$-bases, pseudo-self-dual bases (similar to trace orthogonal bases) and symmetric bases, are defined which in turn are used to define duality preserving maps ...
Szabo, Steve, Ulmer, Felix
core +3 more sources
Molecular Oncology, EarlyView.Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau +8 more
wiley +1 more source
Curl-conforming hierarchical vector bases for triangles and tetrahedra
, 2011 A new family of hierarchical vector bases is proposed for triangles and tetrahedra. These functions span the curl-conforming reduced-gradient spaces of Nédélec.
Andriulli, F.P. +2 more
core +3 more sources
FEBS Open Bio, EarlyView.Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley +1 more source
Non-Intrusive Reduced-Order Modeling Based on Parametrized Proper Orthogonal Decomposition
Energies, 2023 A new non-intrusive reduced-order modeling method based on space-time parameter decoupling for parametrized time-dependent problems is proposed. This method requires the preparation of a database comprising high-fidelity solutions.
Teng Li +4 more
doaj +1 more source
, 1998 Quantum descriptions of many complex systems are formulated most naturally in bases of states that are not mutually orthogonal. We introduce a general and powerful yet simple approach that facilitates solving such models exactly by embedding the non ...
A. Cheong +32 more
core +1 more source
FEBS Open Bio, EarlyView.ERα splice variant ERα∆7 lacks the C‐terminus, and its expression may change phenotypes of breast cancers. Our results showed that ERα∆7 is found in the luminal A subtype, and elevated ERα∆7 levels are linked to improved cell survival with lower proliferation and migration.
Long Wai Tsui +10 more
wiley +1 more source
MathematicsThis paper studies the existence and construction of bases consisting of tangential and anisotropic vectors in finite-dimensional quadratic spaces over fields of characteristic different from two.
Alexander Leones +3 more
doaj +1 more source