Results 161 to 170 of about 51,455 (301)

Aptamer Engineering: Strategies for Discovering Functional Nucleic Acids for Next‐Generation Diagnostics and Biosensing

open access: yesAdvanced Science, Volume 13, Issue 2, 9 January 2026.
The advent of aptamers has highlighted their potential as alternatives to antibodies, overcoming limitations of structural instability and production cost. However, conventional approaches such as SELEX remain slow and labor‐intensive. This review examines recent advances in aptamer engineering, emphasizing in vitro and AI‐driven in silico strategies ...
John V. L. Nguyen   +5 more
wiley   +1 more source

Flow Cytometry: Advances, Challenges and Trends

open access: yesBioEssays, Volume 48, Issue 1, January 2026.
Recent advances in flow cytometry span hardware, data processing, and AI‐driven analytics. Emerging modalitiesincluding spectral, imaging, mass, and nano/EV cytometryenable higher‐parameter and small‐particle detection. Integrated machine learning drives a shift from manual gating toward automated multi‐omics workflows.
J. Paul Robinson   +2 more
wiley   +1 more source

Advances and Applications of Spatial Proteomics: From Organellar Maps to Clinical Translation

open access: yesChemBioChem, Volume 27, Issue 1, January 2026.
Spatial proteomics provides high‐resolution maps of protein localization and trafficking by combining advanced mass spectrometry with complementary imaging and computational tools. Emerging low‐input and automated workflows are expanding its applicability to challenging clinical samples, supporting mechanistic disease research and biomarker discovery ...
Chiara Bernardini   +2 more
wiley   +1 more source

Selection and Characterization of SARS‐CoV‐2 Spike Binding Clickmers

open access: yesChemBioChem, Volume 27, Issue 1, January 2026.
Split‐combine click‐systematic evolution of ligands by exponential enrichment against wild‐type SARS‐CoV‐2 spike glycoprotein yields benzofuran‐ and indole‐functionalized DNA aptamers (clickmers). These clickmers retain specific binding to multiple variants with nanomolar affinity, and the 31 nt indole‐functionalized truncate T2 retains binding to ...
Nima Moradzadeh   +7 more
wiley   +1 more source

Implementasi dan Evaluasi Kinerja Orthogonal Frequency Division Multiplexing (OFDM) Menggunakan WARP

open access: yesJurnal Teknik ITS, 2015
Salah satu permasalahan dalam perkembangan teknologi telekomunikasi yaitu bagaimana mencapai data rate yang besar namun dengan bandwidth yang tidak lebih besar dari bandwidth koheren kanal untuk menghindari terjadinya Inter-Symbol Interference (ISI ...
Hasan Hasan   +2 more
doaj  

A Transcriptional Map of Human Tonsil Architecture: Beyond the Sum of (Single Cell) Parts

open access: yesEuropean Journal of Immunology, Volume 56, Issue 1, January 2026.
Picture‐book compartmentalization makes tonsillar tissue an ideal model to study spatial immunology. Using single‐molecule imaging (SMI) of whole‐tissue sections, we showcase many an alternative view on tissue composition and architecture that these data and concomitant analyses provide—at the level of single cells, cellular neighborhoods, and ...
Helena L. Crowell   +11 more
wiley   +1 more source

Home - About - Disclaimer - Privacy