Accurate and noninvasive prostate cancer detection using plasma‐derived extracellular vesicle RNA
Plasma extracellular vesicles were captured with WGA‐conjugated magnetic beads and profiled for RNA biomarkers. A three‐RNA panel (NM_024955, NR_047469, and NR_002564) distinguished prostate cancer from healthy controls and benign prostatic hyperplasia, supporting a simple, noninvasive approach to improve prostate cancer detection.
Hanping Wei, Haoran Wu, Wei Feng
wiley +1 more source
BCG vaccination potentiates oxidative phosphorylation in neonatal myeloid‐derived suppressor cells
BCG vaccination enhances oxidative phosphorylation in neonatal MDSCs, impairing their immunosuppressive function. It upregulates electron transport chain genes and mitochondrial activity, increasing ATP and oxygen consumption. Pharmacological OXPHOS inhibition partially restores suppressive capacity, confirming causality.
Yingying Chen, Hui Li
wiley +1 more source
Geometric Optimization and Structural Analysis of Cable-Braced Gridshells on Freeform Surfaces
In freeform surface grid structures, quadrilateral meshes offer high visual transparency and simple joint connections, but their structural stability is relatively limited.
Xinye Li, Qilin Zhang
doaj +1 more source
Optimal Waveforms Design for Ultra-Wideband Impulse Radio Sensors
Ultra-wideband impulse radio (UWB-IR) sensors should comply entirely with the regulatory spectral limits for elegant coexistence. Under this premise, it is desirable for UWB pulses to improve frequency utilization to guarantee the transmission ...
Chong Zhao +4 more
doaj +1 more source
General Orthogonality for Orthogonal Polynomials
The bound state wave functions for all the known exactly solvable potentials can be expressed in terms of orthogonal polynomials because the polynomials always satisfy the boundary conditions with a proper weight function. The orthogonality of polynomials is of great importance because the orthogonality characterizes the wave functions and consequently
openaire +2 more sources
Orthogonality of quasi-orthogonal polynomials
A result of P?lya states that every sequence of quadrature formulas Qn(f) with n nodes and positive Cotes numbers converges to the integral I(f) of a continuous function f provided Qn(f) = I(f) for a space of algebraic polynomials of certain degree that depends on n.
Bracciali, Cleonice F. +2 more
openaire +4 more sources
Neurologic Manifestations of Long COVID Affect Adult Females More Severely Than Males
ABSTRACT Objective To characterize differences in neurologic manifestations of postacute sequelae of SARS‐CoV‐2 infection (Neuro‐PASC) between females and males. Methods Cross‐sectional study of the first consecutive 261 posthospitalization Neuro‐PASC (PNP) and 2068 nonhospitalized Neuro‐PASC (NNP) patients evaluated at the Neuro‐COVID clinic between ...
Hannah Kopinsky +5 more
wiley +1 more source
Diverse Subset Selection via Norm-Based Sampling and Orthogonality
Large annotated datasets are crucial for the success of deep learning, but labeling data can be prohibitively expensive in domains such as medical imaging.
Noga Bar, Raja Giryes
doaj +1 more source
SET-VALUED ORTHOGONALITY AND NEARNESS [PDF]
International audienceWe introduce nearness and orthogonality between set-valued map-pings, extending the Campanato nearness and the Birkoff-James orthogonality of single-valued ...
Ernst, Octavian +3 more
core +1 more source
White Matter and Perivascular Imaging Changes in Alzheimer's Disease and Cerebral Amyloid Angiopathy
ABSTRACT Objective Peak‐width of skeletonized mean diffusivity (PSMD) and diffusion tensor imaging–analysis along the perivascular space (DTI‐ALPS), reflecting white matter integrity and glymphatic function, are altered in Alzheimer's disease (AD).
Debina Laishram +3 more
wiley +1 more source

