Results 71 to 80 of about 176,435 (287)

Exon 7 splicing of ERα predicts poor prognosis and increases phenotypic heterogeneity in luminal a subtype breast cancer

open access: yesFEBS Open Bio, EarlyView.
ERα splice variant ERα∆7 lacks the C‐terminus, and its expression may change phenotypes of breast cancers. Our results showed that ERα∆7 is found in the luminal A subtype, and elevated ERα∆7 levels are linked to improved cell survival with lower proliferation and migration.
Long Wai Tsui   +10 more
wiley   +1 more source

Some results on generalized finite operators and range kernel orthogonality in Hilbert spaces

open access: yesDemonstratio Mathematica, 2021
Let ℋ{\mathcal{ {\mathcal H} }} be a complex Hilbert space and ℬ(ℋ){\mathcal{ {\mathcal B} }}\left({\mathcal{ {\mathcal H} }}) denotes the algebra of all bounded linear operators acting on ℋ{\mathcal{ {\mathcal H} }}.
Mesbah Nadia   +2 more
doaj   +1 more source

Mutually orthogonal unitary and orthogonal matrices

open access: yesLinear Algebra and its Applications
16 pages, no ...
Zhiwei Song, Lin Chen, Saiqi Liu
openaire   +3 more sources

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

open access: yesFEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill   +4 more
wiley   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

open access: yesFEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane   +11 more
wiley   +1 more source

Relatively Orthocomplemented Skew Nearlattices in Rickart Rings

open access: yesDemonstratio Mathematica, 2015
A class of (right) Rickart rings, called strong, is isolated. In particular, every Rickart *-ring is strong. It is shown in the paper that every strong Rickart ring R admits a binary operation which turns R into a right normal band having an upper bound ...
Cīırulis Jānis
doaj   +1 more source

Quantum Stabilizer Codes from Maximal Curves

open access: yes, 2013
A curve attaining the Hasse-Weil bound is called a maximal curve. Usually classical error-correcting codes obtained from a maximal curve have good parameters.
Jin, Lingfei
core   +1 more source

Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis

open access: yesFEBS Open Bio, EarlyView.
Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho   +4 more
wiley   +1 more source

Glymphatic Dysfunction Reflects Post‐Concussion Symptoms: Changes Within 1 Month and After 3 Months

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Mild traumatic brain injury (mTBI) may alter glymphatic function; however, its progression and variability remain obscure. This study examined glymphatic function following mTBI within 1 month and after 3 months post‐injury to determine whether variations in glymphatic function are associated with post‐traumatic symptom severity ...
Eunkyung Kim   +3 more
wiley   +1 more source

Modeling of vibration for functionally graded beams

open access: yesOpen Mathematics, 2016
In this study, a vibration problem of Euler-Bernoulli beam manufactured with Functionally Graded Material (FGM), which is modelled by fourth-order partial differential equations with variable coefficients, is examined by using the Adomian Decomposition ...
Yiğit Gülsemay   +2 more
doaj   +1 more source

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