Results 71 to 80 of about 35,860 (292)

Partial FAK suppression promotes tumor growth, an effect reversed by macrophage p110δ PI3K inactivation

open access: yesMolecular Oncology, EarlyView.
Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou   +4 more
wiley   +1 more source

Orthogonality in multiway classifications [PDF]

open access: yes, 1986
We point out the difference between weak orthogonality and strict orthogonality of two factors when all other factors (if any) have been eliminated. Necessary and sufficient conditions for weak orthogonality are obtained, and a simple method of computing
K.R. Shah   +3 more
core   +1 more source

Paclitaxel induces NM2‐dependent cellular contraction through GEF‐H1 dissociation from microtubules and RhoA/ROCK activation in cancer cells

open access: yesMolecular Oncology, EarlyView.
Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez   +5 more
wiley   +1 more source

3D positioning scheme exploiting nano-scale IR-UWB orthogonal pulses

open access: yesNanoscale Research Letters, 2011
In these days, the development of positioning technology for realizing ubiquitous environments has become one of the most important issues. The Global Positioning System (GPS) is a well-known positioning scheme, but it is not suitable for positioning in ...
Kim Nammoon, Kim Youngok
doaj  

Utilizing code orthogonality information for interference suppression in UTRA downlink [PDF]

open access: yes, 2005
This paper suggests the use of code orthogonality information in an iterative, zero forcing interference suppression scheme. This simple scheme is applicable in UTRA downlink conditions.
Hunukumbure, MR, Beach, MA, Webber, JL
core  

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

open access: yesFEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

open access: yesFEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill   +4 more
wiley   +1 more source

The Stochastic Evolution of Financial Asset Prices

open access: yesMathematics
This paper examines the relationship between dependence and independence alternatives in general stochastic processes and explores the duality between the true (yet unknown) stochastic process and the functional representation that fits the observed data.
Ioannis Paraskevopoulos, Alvaro Santos
doaj   +1 more source

Some results on generalized finite operators and range kernel orthogonality in Hilbert spaces

open access: yesDemonstratio Mathematica, 2021
Let ℋ{\mathcal{ {\mathcal H} }} be a complex Hilbert space and ℬ(ℋ){\mathcal{ {\mathcal B} }}\left({\mathcal{ {\mathcal H} }}) denotes the algebra of all bounded linear operators acting on ℋ{\mathcal{ {\mathcal H} }}.
Mesbah Nadia   +2 more
doaj   +1 more source

Orthogonal AMP

open access: yesIEEE Access, 2017
accepted for publication in IEEE ...
Junjie Ma 0001, Li Ping 0001
openaire   +4 more sources

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