Results 81 to 90 of about 25,011 (183)

The Great Dividing Range as a driver of genetic divergence in a low‐dispersing dragonfly

open access: yesEcological Entomology, EarlyView.
Population genomic analyses revealed low genetic differentiation and no discrete population structure across the Great Dividing Range, indicating widespread gene flow in Synthemis eustalacta. Genetic divergence was associated with environmental gradients, elevation and landscape resistance rather than geographic distance, supporting isolation by ...
Aaron M. Goodman   +20 more
wiley   +1 more source

Phylogenetic reconstruction of orthology, paralogy, and conserved synteny for dog and human.

open access: yesPLoS Computational Biology, 2006
Accurate predictions of orthology and paralogy relationships are necessary to infer human molecular function from experiments in model organisms. Previous genome-scale approaches to predicting these relationships have been limited by their use of protein
Leo Goodstadt, Chris P Ponting
doaj   +1 more source

Ploidy‐dependent modulation of DNA replication kinetics in Xenopus

open access: yesThe FEBS Journal, EarlyView.
Using an interspecies replication system with Xenopus frog species of different ploidy levels, we investigated how DNA replication adapts to polyploidization. While replication was slower in tetraploid than in diploid nuclei, dodecaploid nuclei unexpectedly replicated faster than tetraploid nuclei. Our findings show that increasing genome size does not
Hemalatha Narassimprakash   +4 more
wiley   +1 more source

Calm in the midst of the storm: inferring gene expression stability in flowering plants

open access: yesFrontiers in Plant Science
IntroductionGene expression in plants is inherently dynamic, shifting rapidly during development and in response to environmental stimuli. However, many essential cellular processes require remarkable transcriptomic stability.
Anna V. Klepikova   +8 more
doaj   +1 more source

Assessing performance of orthology detection strategies applied to eukaryotic genomes.

open access: yesPLoS ONE, 2007
Orthology detection is critically important for accurate functional annotation, and has been widely used to facilitate studies on comparative and evolutionary genomics.
Feng Chen   +3 more
doaj   +1 more source

Transcriptomic and proteomic signatures underlying nymphal adaptation and foam production in the forage pest Mahanarva spectabilis

open access: yesInsect Molecular Biology, EarlyView.
RNA‐seq and Batelli gland proteomics of fifth‐instar Mahanarva spectabilis nymphs reveal transcripts and proteins associated with xylem feeding, foam production and environmental interaction. Functional annotation identified genes involved in osmoregulation, detoxification, chemosensation and stress responses, while proteomic analysis confirmed ...
Monique da Silva Bonjour   +8 more
wiley   +1 more source

OGO: an ontological approach for integrating knowledge about orthology

open access: yesBMC Bioinformatics, 2009
Background There exist several information resources about orthology of genes and proteins, and there are also systems for querying those resources in an integrated way.
Fernandez-Breis Jesualdo   +2 more
doaj   +1 more source

Phylogenetic and functional assessment of orthologs inference projects and methods.

open access: yesPLoS Computational Biology, 2009
Accurate genome-wide identification of orthologs is a central problem in comparative genomics, a fact reflected by the numerous orthology identification projects developed in recent years.
Adrian M Altenhoff, Christophe Dessimoz
doaj   +1 more source

Genome assembly of Elcysma westwoodi provides insights into host‐plant cyanogenic glucoside detoxification and chemical defence gene evolution

open access: yesInsect Molecular Biology, EarlyView.
A chromosome‐level genome of Elcysma westwoodi was assembled. The genome encodes 272 detoxification‐related genes. A single‐copy bCAS was retained for cyanide detoxification. CYP405A and CYP332A were recruited into cyanogenic defence evolution. UGT33A retained a conserved GT‐B fold and catalytic domains.
Minyoung Choi, Murtaza Khan, Juil Kim
wiley   +1 more source

Integrative transcriptomic and machine learning approaches reveal candidate genes for silk and venom production in Bibionomorpha (Diptera)

open access: yesInsect Molecular Biology, EarlyView.
Multi‐species transcriptomics and deep learning identified candidate genes associated with silk and venom production in Bibionomorpha. Venom‐associated genes were enriched in proteases, inhibitors and pore‐forming proteins, whereas silk‐related genes showed chitin‐binding and peritrophin domains. Integrating co‐expression networks, machine learning and
Daniel Kenji Matuo   +2 more
wiley   +1 more source

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