Results 61 to 70 of about 28,177 (251)

Reconstruction of the evolutionary landscape of biological processes involved in the early stages of the metastatic cascade [PDF]

Genetics and Molecular Biology
Metastasis is not a de novo functional module innovation but rather the pathological redeployment of deeply conserved biological programs. Here, we reconstruct the evolutionary landscape of biological functions involved in the early stages of the ...
Gleison M. Azevedo, Epitácio Farias, João Vitor F. Cavalcante, Rafaella S. Ferraz, Bruno William, Diego M. Coelho, Rodrigo J.S. Dalmolin   +6 more
doaj   +2 more sources

Metagenomic Association Uncovers Host Genotype‐Structured Rhizobacterial Networks and Novel Taxa That Enhance Soybean Salt Tolerance

Advanced Science, EarlyView.
An STI‐guided metagenomic association framework links soybean salt‐tolerance phenotypes with rhizosphere microbiome composition and network organization in natural saline soils. The approach identifies candidate beneficial taxa, including Thalassospira xiamenensis, and provides an efficient strategy for mining stress‐protective microbes from native ...
Yu Luo, Feng‐Li Kang, Qi‐Min Li, Wei‐Cai Yang   +3 more
wiley   +1 more source

Intermittent Fasting Restores Cardiac Lipid Homeostasis in Diabetic Cardiomyopathy in Association With Akkermansia Muciniphila and 1‐methyl‐L‐histidine

Advanced Science, EarlyView.
Intermittent fasting reshapes the gut microbiota in diabetic cardiomyopathy, restoring Akkermansia muciniphila and the microbiota‐associated metabolite 1‐methyl‐L‐histidine. This shift is linked to improved cardiac lipid homeostasis, reduced lipid peroxidation, and attenuated myocardial injury, highlighting a gut microbiota–metabolite–lipid axis in ...
Kaiyuan Jiang, Fen Xiong, Yiwen Peng, Lingfei Meng, Xinran Wang, Yingruo Xu, Tian Tang, Hongchang Gao   +7 more
wiley   +1 more source

quercusTOA: integrating functional annotations and comparative genomics across oak lineages

Frontiers in Bioinformatics
Oaks (Quercus L.) are key components of Northern Hemisphere Forest ecosystems, yet the integration of their rapidly growing genomic resources remains challenging. Here, we present quercusTOA, a genomic and functional resource that integrates nine Quercus
Fernando Mora-Márquez, Mikel Hurtado, Mikel Hurtado, Unai López de Heredia   +3 more
doaj   +1 more source

PICKLE 3.0: enriching the human meta-database with the mouse protein interactome extended via mouse–human orthology

Bioinform., 2020
Summary The PICKLE 3.0 upgrade refers to the enrichment of this human protein–protein interaction (PPI) meta-database with the mouse protein interactome.
Georgios N. Dimitrakopoulos, M. Klapa, N. Moschonas   +2 more
semanticscholar   +1 more source

The axioms for implication in orthologic [PDF]

Czechoslovak Mathematical Journal, 2008
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
openaire   +1 more source

Revolutionising Agricultural Sustainability: New ‘Furrow Tillage’ can Mitigate Short‐Term Soil‐to‐Atmosphere CO2 Flux and Promote Soil‐Plant‐Microbe Health

Advanced Science, EarlyView.
Furrow tillage resolves the conventional‐vs.‐no‐tillage trade‐off by simultaneously cutting CO2 efflux to 2.0–3.0 g C m−2 d−1 and unlocking high nutrient availability for the rice rhizosphere. This scalable agronomic solution strengthens soil health, enhances plant physiology, reshapes microbial metabolism, and shifts paddy systems toward a net ...
Arnab Majumdar, Munish Kumar Upadhyay, Argha Ghosh, Rakesh Biswas, Ioly Kotta Loizou, Martin Buck, Mark Tibbett, Biswajit Giri, Debojyoti Moulick, Manoj Kumar Jaiswal, Tarit Roychowdhury   +10 more
wiley   +1 more source

Identification of mammalian orthologs using local synteny

BMC Genomics, 2009
Background Accurate determination of orthology is central to comparative genomics. For vertebrates in particular, very large gene families, high rates of gene duplication and loss, multiple mechanisms of gene duplication, and high rates of ...
Nelson Craig E, Mandoiu Ion I, Jun Jin
doaj   +1 more source

MetaPhOrs 2.0: integrative, phylogeny-based inference of orthology and paralogy across the tree of life

Nucleic Acids Res., 2020
Inferring homology relationships across genes in different species is a central task in comparative genomics. Therefore, a large number of resources and methods have been developed over the years.
U. Chorostecki, M. Molina, Leszek P. Pryszcz, T. Gabaldón   +3 more
semanticscholar   +1 more source

Transposable Element–Driven PIEZO Mutation Enhances Locust Flight in Plateau Hypoxia

Advanced Science, EarlyView.
Why transposable elements (TEs) persisted or expanded in genomes remains a mystery. Using integrated analysis of TE macro‐ and microevolution in locusts, our results showed that thousands of TE insertions promoted widespread adaptive variation. Subfamilies of candidate adaptive TEs amplified and reshaped species‐level genomic architecture.
Xuanzhao Li, Ying Liu, Longsheng Xing, Xianliang Huang, Yingming Sun, Lei Yue, Yuze Zhang, Huilong Du, Bing Chen   +8 more
wiley   +1 more source