Results 41 to 50 of about 28,177 (251)

Proteinortho6: pseudo-reciprocal best alignment heuristic for graph-based detection of (co-)orthologs

open access: yesFrontiers in Bioinformatics, 2023
Proteinortho is a widely used tool to predict (co)-orthologous groups of genes for any set of species. It finds application in comparative and functional genomics, phylogenomics, and evolutionary reconstructions.
Paul Klemm   +6 more
doaj   +1 more source

An Implication in Orthologic

open access: yesInternational Journal of Theoretical Physics, 2005
We involve a certain propositional logic based on ortholattices. We characterize the implicational reduct of such a logic and we show that its algebraic counterpart is the so-called orthosemilattice. Properties of congruences and congruence kernels of these algebras are described.
Chajda, I., Halaš, R.
openaire   +2 more sources

Ortholog-Finder: A Tool for Constructing an Ortholog Data Set [PDF]

open access: yesGenome Biology and Evolution, 2016
Orthologs are widely used for phylogenetic analysis of species; however, identifying genuine orthologs among distantly related species is challenging, because genes obtained through horizontal gene transfer (HGT) and out-paralogs derived from gene duplication before speciation are often present among the predicted orthologs.
Horiike, Tokumasa   +4 more
openaire   +2 more sources

Protein-Gene Orthology in Baculoviridae: An Exhaustive Analysis to Redefine the Ancestrally Common Coding Sequences

open access: yesViruses, 2023
Baculoviruses are entomopathogens that carry large, double-stranded circular DNA genomes and infect insect larvae of Lepidoptera, Hymenoptera and Diptera, with applications in the biological control of agricultural pests, in the production of recombinant
Carolina Susana Cerrudo   +5 more
doaj   +1 more source

eggNOG 4.5: a hierarchical orthology framework with improved functional annotations for eukaryotic, prokaryotic and viral sequences

open access: yesNucleic Acids Res., 2015
eggNOG is a public resource that provides Orthologous Groups (OGs) of proteins at different taxonomic levels, each with integrated and summarized functional annotations.
J. Huerta-Cepas   +12 more
semanticscholar   +1 more source

OMA orthology in 2021: website overhaul, conserved isoforms, ancestral gene order and more

open access: yesNucleic Acids Res., 2020
OMA is an established resource to elucidate evolutionary relationships among genes from currently 2326 genomes covering all domains of life. OMA provides pairwise and groupwise orthologs, functional annotations, local and global gene order conservation ...
A. Altenhoff   +11 more
semanticscholar   +1 more source

A Reliable Neighbor-Based Method for Identifying Essential Proteins by Integrating Gene Expressions, Orthology, and Subcellular Localization Information

open access: yesTsinghua Science and Technology, 2016
Essential proteins are those necessary for the survival or reproduction of species and discovering such essential proteins is fundamental for understanding the minimal requirements for cellular life, which is also meaningful to the disease study and drug
Min Li   +5 more
doaj   +1 more source

Disparate Inventories of Hypoxia Gene Sets Across Corals Align With Inferred Environmental Resilience

open access: yesFrontiers in Marine Science, 2022
Aquatic deoxygenation has been flagged as an overlooked but key factor contributing to mass bleaching-induced coral mortality. During deoxygenation events triggered by coastal nutrient pollution and ocean warming, oxygen supplies lower to concentrations ...
Rachel Alderdice   +5 more
doaj   +1 more source

Comprehensive Functional Annotation of Metagenomes and Microbial Genomes Using a Deep Learning-Based Method

open access: yesmSystems, 2023
Comprehensive protein function annotation is essential for understanding microbiome-related disease mechanisms in the host organisms. However, a large portion of human gut microbial proteins lack functional annotation.
Mary Maranga   +8 more
doaj   +1 more source

Complete Characterization of Incorrect Orthology Assignments in Best Match Graphs [PDF]

open access: yesJournal of Mathematical Biology, 2020
Genome-scale orthology assignments are usually based on reciprocal best matches. In the absence of horizontal gene transfer (HGT), every pair of orthologs forms a reciprocal best match. Incorrect orthology assignments therefore are always false positives
David Schaller   +3 more
semanticscholar   +1 more source

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