Results 21 to 30 of about 28,177 (251)

OMA orthology in 2024: improved prokaryote coverage, ancestral and extant GO enrichment, a revamped synteny viewer and more in the OMA Ecosystem

open access: yesNucleic Acids Research, 2023
In this update paper, we present the latest developments in the OMA browser knowledgebase, which aims to provide high-quality orthology inferences and facilitate the study of gene families, genomes and their evolution.
A. Altenhoff   +11 more
semanticscholar   +1 more source

GENESPACE tracks regions of interest and gene copy number variation across multiple genomes

open access: yeseLife, 2022
The development of multiple chromosome-scale reference genome sequences in many taxonomic groups has yielded a high-resolution view of the patterns and processes of molecular evolution.
John T Lovell   +8 more
doaj   +1 more source

Orthologics for Cones

open access: yesCoRR, 2020
extended version of AI2020 ...
Mena Leemhuis   +2 more
openaire   +2 more sources

Development of a knowledge graph framework to ease and empower translational approaches in plant research: a use-case on grain legumes

open access: yesFrontiers in Artificial Intelligence, 2023
While the continuing decline in genotyping and sequencing costs has largely benefited plant research, some key species for meeting the challenges of agriculture remain mostly understudied.
Baptiste Imbert   +6 more
doaj   +1 more source

SonicParanoid2: fast, accurate, and comprehensive orthology inference with machine learning and language models

open access: yesbioRxiv, 2023
Accurate inference of orthologous genes constitutes a prerequisite for comparative and evolutionary genomics. SonicParanoid is one of the fastest tools for orthology inference; however, its scalability and accuracy have been hampered by time-consuming ...
Salvatore Cosentino, W. Iwasaki
semanticscholar   +1 more source

Improving split reporters of protein-protein interactions through orthology-based protein engineering

open access: yesbioRxiv, 2023
Protein-protein interactions (PPI) can be detected through selective complementation of split fluorescent reporters made of two complementary fragments that reassemble into a functional fluorescent reporter when in close proximity.
Louise-Marie Rakotoarison   +3 more
semanticscholar   +1 more source

Species-agnostic transfer learning for cross-species transcriptomics data integration without gene orthology

open access: yesbioRxiv, 2023
Novel hypotheses in biomedical research are often developed or validated in model organisms such as mice and zebrafish and thus play a crucial role, particularly in studying disease mechanisms and treatment responses.
Young-Hee Park   +2 more
semanticscholar   +1 more source

Orthology prediction at scalable resolution by phylogenetic tree analysis

open access: yesBMC Bioinformatics, 2007
Background Orthology is one of the cornerstones of gene function prediction. Dividing the phylogenetic relations between genes into either orthologs or paralogs is however an oversimplification.
Huynen Martijn A   +3 more
doaj   +1 more source

Internet News Headlines: Ontological and Orthological Aspects

open access: yesНаучный диалог, 2021
The author presents the results of a multidimensional analysis of Internet news headlines based on the headings of the Yandex news aggregator. The issue of the text status of news headlines is considered.
E. N. Shirokova
doaj   +1 more source

AsgeneDB: a curated orthology arsenic metabolism gene database and computational tool for metagenome annotation

open access: yesNAR Genomics and Bioinformatics, 2022
Arsenic (As) is the most ubiquitous toxic metalloid in nature. Microbe-mediated As metabolism plays an important role in global As biogeochemical processes, greatly changing its toxicity and bioavailability.
Xinwei Song   +8 more
semanticscholar   +1 more source

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