Results 11 to 20 of about 30,147 (189)
Orthology prediction at scalable resolution by phylogenetic tree analysis [PDF]
BMC Bioinformatics, 2007 Background Orthology is one of the cornerstones of gene function prediction. Dividing the phylogenetic relations between genes into either orthologs or paralogs is however an oversimplification.
Huynen Martijn A +3 more
doaj +2 more sources
Domainoid: domain-oriented orthology inference [PDF]
BMC Bioinformatics, 2019 Background Orthology inference is normally based on full-length protein sequences. However, most proteins contain independently folding and recurring regions, domains.
Emma Persson +3 more
doaj +2 more sources
OrthoInspector: comprehensive orthology analysis and visual exploration [PDF]
BMC Bioinformatics, 2011 Background The accurate determination of orthology and inparalogy relationships is essential for comparative sequence analysis, functional gene annotation and evolutionary studies.
Lecompte Odile +3 more
doaj +2 more sources
POInTbrowse: orthology prediction and synteny exploration for paleopolyploid genomes
BMC Bioinformatics, 2023 We describe POInTbrowse, a web portal that gives access to the orthology inferences made for polyploid genomes with POInT, the Polyploidy Orthology Inference Tool.
Mustafa Siddiqui, Gavin C. Conant
doaj +2 more sources
Orthology detection combining clustering and synteny for very large datasets. [PDF]
PLoS ONE, 2014 The elucidation of orthology relationships is an important step both in gene function prediction as well as towards understanding patterns of sequence evolution. Orthology assignments are usually derived directly from sequence similarities for large data
Marcus Lechner +8 more
doaj +3 more sources
OGO: an ontological approach for integrating knowledge about orthology
BMC Bioinformatics, 2009 Background There exist several information resources about orthology of genes and proteins, and there are also systems for querying those resources in an integrated way.
Fernandez-Breis Jesualdo +2 more
doaj +2 more sources
Assessment of orthologous splicing isoforms in human and mouse orthologous genes [PDF]
BMC Genomics, 2010 Background Recent discoveries have highlighted the fact that alternative splicing and alternative transcripts are the rule, rather than the exception, in metazoan genes.
Horner David S +4 more
doaj +6 more sources
The Orthology Road: Theory and Methods in Orthology Analysis [PDF]
, 2013 The evolution of biological species depends on changes in genes. Among these changes are the gradual accumulation of DNA mutations, insertions and deletions, duplication of genes, movements of genes within and between chromosomes, gene losses and gene ...
Hernandez Rosales, Maribel
core +3 more sources
BMC Bioinformatics, 2012 Background The concept of orthology is key to decoding evolutionary relationships among genes across different species using comparative genomics. QuartetS is a recently reported algorithm for large-scale orthology detection.
Yu Chenggang +3 more
doaj +1 more source