Results 61 to 70 of about 21,900 (205)

Meta-transcriptomics for the diversity of tick-borne virus in Nujiang, Yunnan Province

Frontiers in Cellular and Infection Microbiology, 2023
Ticks, an arthropod known for transmitting various pathogens such as viruses, bacteria, and fungi, pose a perpetual public health concern. A total of 2,570 ticks collected from Nujiang Prefecture in Yunnan Province between 2017 and 2022 were included in ...
Juan Wang, Jing Wang, Guopeng Kuang, Weichen Wu, Lifen Yang, Weihong Yang, Hong Pan, Xi Han, Tian Yang, Mang Shi, Yun Feng, Yun Feng, Yun Feng   +12 more
doaj   +1 more source

Evolution of H5N1 Cross‐Species Transmission: Adaptive Mutations Driving Avian‐to‐Human Infection

Advanced Genetics, Volume 7, Issue 1, March 2026.
This review synthesizes current knowledge on the molecular mechanisms underpinning H5N1's host adaptation, focusing on key mutations in viral proteins. Critical mutations are discussed in detail, highlighting their roles in altering receptor specificity, promoting antiviral resistance, and expanding viral tropism. The review underscores the urgent need
Wenxin Man, Lin Du, Ying Liu, Zehan Pang, Hongyan Zhu, Bixia Hong, Zhichao Xu, Huahao Fan   +7 more
wiley   +1 more source

A temperature sensitive live-attenuated canine influenza virus H3N8 vaccine [PDF]

, 2017
Canine influenza is a respiratory disease of dogs caused by canine influenza virus (CIV). CIV subtypes responsible for influenza in dogs include H3N8, which originated from the transfer of H3N8 equine influenza virus to dogs; and the H3N2 CIV, which is ...
Chauché, Caroline, Huang, Kai, Martínez-Sobrido, Luis, Murcia, Pablo R., Nogales, Aitor, Parrish, Colin R., Reilly, Emma C., Rodriguez, Laura, Topham, David J.   +8 more
core   +1 more source

Drivers of Viral Diversity and Sharing in Marine Mammals

Molecular Ecology, Volume 35, Issue 6, March 2026.
ABSTRACT Knowledge of viral infection in marine mammals, a group severely threatened by human activity, is largely limited to the pathology and epidemiology of few endemic viruses. The recent emergence in marine mammals of high‐consequence viruses, such as H5N1 avian influenza and rabies, underscores the importance of understanding the ecology of viral
Matthew J. Arnold, Laura M. Bergner, Haris Malik, Mariel ten Doeschate, Nicholas J. Davison, Andrew Brownlow, Nardus Mollentze, Simon A. Babayan, Daniel G. Streicker   +8 more
wiley   +1 more source

Genome‐Wide Codon Reprogramming Enables a Multifactorially Attenuated Influenza Vaccine with Broad Cross‐Protection

Advanced Science, Volume 13, Issue 9, 13 February 2026.
Genome‐wide codon reprogramming of influenza A virus introduces 1956 synonymous mutations across five segments and elevates CpG content, causing defective NA packaging, loss of NS1 accumulation, and enhanced ZAP‐mediated antiviral responses without affecting RNA or protein synthesis. These mechanisms result in profound attenuation and potent homologous
Yang Wang, Tianxin Ma, Yujiao He, Qinming Li, Kailin Mai, Minying Mo, Chenyang Cao, Jiahui Li, Pei Feng, Jiaojiao Peng, Jing Sun, Weiqi Pan, Zifeng Yang, Ling Chen   +13 more
wiley   +1 more source

The 5' ends of Thogoto virus (Orthomyxoviridae) mRNAs are homogeneous in both length and sequence [PDF]

Journal of Virology, 1996
Thogoto (THO) virus is a tick-borne member of the Orthomyxoviridae whose genome consists of six segments of linear, negative sense, single-stranded RNA. To gain insight into the mechanism by which viral mRNA transcripts are initiated, poly(A)+ RNA isolated from THO virus-infected cells was characterized by (i) primer extension experiments, (ii ...
C, Albo, J, Martín, A, Portela
openaire   +2 more sources

Clinical Analysis of Neonatal Influenza in the Neonatal Intensive Care Unit: A Retrospective Study

Immunity, Inflammation and Disease, Volume 14, Issue 2, February 2026.
ABSTRACT Background To describe the clinical characteristics, treatment, and outcomes of neonatal influenza. Methods Retrospectively analyzed clinical data on 26 neonates who were diagnosed with neonatal influenza by positive influenza nasopharyngeal swab antigen tests, and admitted to the neonatal intensive care unit of Sichuan Province Chengdu ...
Min Zhou, Jia Chen, Jing Zhao, Zhuli Yu, Mengjuan Feng, Xiang Qiu   +5 more
wiley   +1 more source

The N-terminal domain of the arenavirus L protein is an RNA endonuclease essential in mRNA transcription.

PLoS Pathogens, 2010
Arenaviridae synthesize viral mRNAs using short capped primers presumably acquired from cellular transcripts by a 'cap-snatching' mechanism. Here, we report the crystal structure and functional characterization of the N-terminal 196 residues (NL1) of the
Benjamin Morin, Bruno Coutard, Michaela Lelke, François Ferron, Romy Kerber, Saïd Jamal, Antoine Frangeul, Cécile Baronti, Rémi Charrel, Xavier de Lamballerie, Clemens Vonrhein, Julien Lescar, Gérard Bricogne, Stephan Günther, Bruno Canard   +14 more
doaj   +1 more source

Sexual Transmission of Arboviruses: A Systematic Review

Viruses, 2020
Arthropod-borne viruses (arboviruses) are primarily maintained in nature in transmission cycles between hematophagous arthropods and vertebrate hosts, but an increasing number of arboviruses have been isolated from or indirectly detected in the ...
Bradley J. Blitvich, Tereza Magalhaes, S. Viridiana Laredo-Tiscareño, Brian D. Foy   +3 more
doaj   +1 more source

E-Predict: a computational strategy for species identification based on observed DNA microarray hybridization patterns [PDF]

, 2005
DNA microarrays may be used to identify microbial species present in environmental and clinical samples. However, automated tools for reliable species identification based on observed microarray hybridization patterns are lacking. We present an algorithm,
Urisman, Anatoly, Fischer, Kael F, Chiu, Charles Y, Kistler, Amy L, Beck, Shoshannah, Wang, David, DeRisi, Joseph L   +6 more
core   +1 more source