Results 61 to 70 of about 21,029 (222)

Use of hemagglutinin and neuraminidase amplicon-based high-throughput sequencing with variant analysis to detect co-infection and resolve identical consensus sequences of seasonal influenza in a university setting

BMC Infectious Diseases, 2021
Background Local transmission of seasonal influenza viruses (IVs) can be difficult to resolve. Here, we study if coupling high-throughput sequencing (HTS) of hemagglutinin (HA) and neuraminidase (NA) genes with variant analysis can resolve strains from ...
Temitope O. C. Faleye, Deborah Adams, Sangeet Adhikari, Helen Sandrolini, Rolf U. Halden, Arvind Varsani, Matthew Scotch   +6 more
doaj   +1 more source

Divergent Influenza-Like Viruses of Amphibians and Fish Support an Ancient Evolutionary Association

Viruses, 2020
Influenza viruses (family Orthomyxoviridae) infect a variety of vertebrates, including birds, humans, and other mammals. Recent metatranscriptomic studies have uncovered divergent influenza viruses in amphibians, fish and jawless vertebrates, suggesting ...
Rhys Parry, Michelle Wille, Olivia M. H. Turnbull, Jemma L. Geoghegan, Edward C. Holmes   +4 more
doaj   +1 more source

Catch, Cut, or Block? Versatile 4‐N‐Derivatized Sialyl Glycosides for Influenza Virus Neuraminidase Detection and Purification

Angewandte Chemie, Volume 137, Issue 25, June 17, 2025.
Sialyl glycosides containing 4‐N‐derivatized sialic acids synthesized by a highly efficient one‐pot two‐enzyme (OP2E) chemoenzymatic sialylation strategy have been shown to be versatile probes. They can resist sialidase cleavage, be selective substrates by influenza sialidases, or be nanomolar substrate analog‐based inhibitors and affinity ligands ...
Yue Yuan, Hai Yu, Anand Kumar Agrahari, Jin Gao, Hyeog Kang, Robert Daniels, Xi Chen   +6 more
wiley   +2 more sources

Influenza in today: direct-acting antiviral therapy

Медицинский совет, 2015
Influenza is an acute infectious disease caused by influenza virus (Orthomyxoviridae family) which affects up to 15% of the world population in the cold season.
T. V. Sologub
doaj   +1 more source

Human Cytomegalovirus Inhibitor AL18 Also Possesses Activity against Influenza A and B Viruses [PDF]

, 2012
AL18, an inhibitor of human cytomegalovirus DNA polymerase, was serendipitously found to also block the interaction between the PB1 and PA polymerase subunits of influenza A virus.
Cruciani, Gabriele, Digard, Paul, Goracci, Laura, Loregian, Arianna, Mercorelli, Beatrice, Muratore, Giulia, Palu, Giorgio   +6 more
core   +1 more source

Viral metagenomics reveals the presence of highly divergent quaranjavirus in Rhipicephalus ticks from Mozambique

Infection Ecology & Epidemiology, 2018
Background: Ticks are primary vectors for many well-known disease-causing agents that affect human and animal populations globally such as tick-borne encephalitis, Crimean-Congo hemorrhagic fever and African swine fever. In this study, viral metagenomics
Harindranath Cholleti, Juliette Hayer, Fernando Chanisso Mulandane, Kerstin Falk, Jose Fafetine, Mikael Berg, Anne-Lie Blomström   +6 more
doaj   +1 more source

Seroprevalence of influenza D virus in selected sample groups of Irish cattle, sheep and pigs

Irish Veterinary Journal, 2019
Influenza D virus (IDV) is a new member of the Orthomyxoviridae family. It was first reported in swine in 2011 and isolated from bovine samples received for routine respiratory disease diagnosis in Ireland during 2014–2016.
Tom O’Donovan, Leah Donohoe, Mariette F. Ducatez, Gilles Meyer, Eoin Ryan   +4 more
doaj   +1 more source

Tempo and mode in the molecular evolution of influenza C [PDF]

, 2010
Influenza C contributes to economic damage caused by working days lost through absence or inefficiency and may occasionally cause an acute respiratory illness in a paediatric setting.
Gatherer, Derek
core   +2 more sources

Avian flu: «for whom the bell tolls»?

Вопросы вирусологии
The family Orthomyxoviridae consists of 9 genera, including Alphainfluenza virus, which contains avian influenza viruses. In two subtypes H5 and H7 besides common low-virulent strains, a specific type of highly virulent avian virus have been described to
Oleg P. Zhirnov, Dmitry K. Lvov
doaj   +1 more source

Respiratory virus mRNA vaccines: mRNA Design, clinical studies, and future challenges

Animal Models and Experimental Medicine, EarlyView.
Abstract Respiratory infectious diseases frequently erupt on a global scale, with RNA viruses, such as SARS‐CoV‐2, RSV, and influenza viruses, posing challenges to vaccine development due to their high mutation rates. Traditional vaccine development cycles are lengthy and struggle to keep pace with rapidly evolving viruses, whereas messenger RNA (mRNA)
Linlin Zheng, Han Feng
wiley   +1 more source