Results 51 to 60 of about 18,885 (141)

The contact process with semi-infected state on the complete graph [PDF]

arXiv, 2017
In this paper we are concerned with the contact process with semi-infected state on the complete graph $C_n$ with $n$ vertices. In our model, each vertex is in one of three states that `healthy', `semi-infected' or `wholly-infected'. Only wholly-infected vertices can infect others. A healthy vertex becomes semi-infected when being infected while a semi-
arxiv  

A mathematical model for the within-host (re)infection dynamics of SARS-CoV-2 [PDF]

arXiv, 2023
Interactions between SARS-CoV-2 and the immune system during infection are complex. However, understanding the within-host SARS-CoV-2 dynamics is of enormous importance, especially when it comes to assessing treatment options. Mathematical models have been developed to describe the within-host SARS-CoV-2 dynamics and to dissect the mechanisms ...
arxiv  

Classifying Latent Infection States in Complex Networks [PDF]

arXiv, 2014
Algorithms for identifying the infection states of nodes in a network are crucial for understanding and containing infections. Often, however, only a relatively small set of nodes have a known infection state. Moreover, the length of time that each node has been infected is also unknown.
arxiv  

A comprehensive overview on the crosstalk between microRNAs and viral pathogenesis and infection

Medicinal Research Reviews, Volume 45, Issue 2, Page 349-425, March 2025.
Abstract Infections caused by viruses as the smallest infectious agents, pose a major threat to global public health. Viral infections utilize different host mechanisms to facilitate their own propagation and pathogenesis. MicroRNAs (miRNAs), as small noncoding RNA molecules, play important regulatory roles in different diseases, including viral ...
Seyedeh Zahra Bahojb Mahdavi, Asiyeh Jebelli, Parisa Shiri Aghbash, Behzad Baradaran, Mohammad Amini, Fatemeh Oroojalian, Nasser Pouladi, Hossein Bannazadeh Baghi, Miguel de la Guardia, Amir Ali Mokhtarzadeh   +9 more
wiley   +1 more source

A compendium of multi-omics data illuminating host responses to lethal human virus infections

Scientific Data
Human infections caused by viral pathogens trigger a complex gamut of host responses that limit disease, resolve infection, generate immunity, and contribute to severe disease or death.
Amie J. Eisfeld, Lindsey N. Anderson, Shufang Fan, Kevin B. Walters, Peter J. Halfmann, Danielle Westhoff Smith, Larissa B. Thackray, Qing Tan, Amy C. Sims, Vineet D. Menachery, Alexandra Schäfer, Timothy P. Sheahan, Adam S. Cockrell, Kelly G. Stratton, Bobbie-Jo M. Webb-Robertson, Jennifer E. Kyle, Kristin E. Burnum-Johnson, Young-Mo Kim, Carrie D. Nicora, Zuleyma Peralta, Alhaji U. N’jai, Foday Sahr, Harm van Bakel, Michael S. Diamond, Ralph S. Baric, Thomas O. Metz, Richard D. Smith, Yoshihiro Kawaoka, Katrina M. Waters   +28 more
doaj   +1 more source

Zoonosis and zooanthroponosis of emerging respiratory viruses

Frontiers in Cellular and Infection Microbiology
Lung infections in Influenza-Like Illness (ILI) are triggered by a variety of respiratory viruses. All human pandemics have been caused by the members of two major virus families, namely Orthomyxoviridae (influenza A viruses (IAVs); subtypes H1N1, H2N2 ...
Ahmed Magdy Khalil, Ahmed Magdy Khalil, Luis Martinez-Sobrido, Ahmed Mostafa, Ahmed Mostafa   +4 more
doaj   +1 more source

Activation and inhibition of sirtuins: From bench to bedside

Medicinal Research Reviews, Volume 45, Issue 2, Page 484-560, March 2025.
Abstract The sirtuin family comprises seven NAD+‐dependent enzymes which catalyze protein lysine deacylation and mono ADP‐ribosylation. Sirtuins act as central regulators of genomic stability and gene expression and control key processes, including energetic metabolism, cell cycle, differentiation, apoptosis, and aging.
Francesco Fiorentino, Emanuele Fabbrizi, Antonello Mai, Dante Rotili   +3 more
wiley   +1 more source

Numerical considerations about the SIR epidemic model with infection age [PDF]

arXiv, 2020
We analyse the infection-age-dependent SIR model from a numerical point of view. First, we present an algorithm for calculating the solution the infection-age-structured SIR model without demography of the background host. Second, we examine how and under which conditions, the conventional SIR model (without infection-age) serves as a practical ...
arxiv  

Potential mechanisms implied in tick infection by arboviruses and their transmission to vertebrate hosts

Integrative Zoology, Volume 20, Issue 2, Page 315-330, March 2025.
We summarize the recent progress in understanding defense mechanisms in specific tissues or sites that are encountered by arboviruses and discuss their possible roles in virus infection or transmission. Abstract Ticks can transmit many pathogens, including arboviruses, to their vertebrate hosts.
Chuanfei YUAN, Qiong XU, Yunjia NING, Qianfeng XIA   +3 more
wiley   +1 more source

Molecular Evolution of the H5 and H7 Highly Pathogenic Avian Influenza Virus Haemagglutinin Cleavage Site Motif

Reviews in Medical Virology, Volume 35, Issue 1, January 2025.
ABSTRACT Avian influenza viruses are ubiquitous in the Anatinae subfamily of aquatic birds and occasionally spill over to poultry. Infection with low pathogenicity avian influenza viruses generally leads to subclinical or mild clinical disease. In contrast, highly pathogenic avian influenza viruses emerge from low pathogenic forms and can cause severe ...
Jasmina M. Luczo, Erica Spackman
wiley   +1 more source