Results 191 to 200 of about 3,052,451 (281)

USP7 Regulates TRPV1 Deubiquitination to Mediate Chondrocyte Ferroptosis and Alleviate Osteoarthritis

open access: yesThe Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Osteoarthritis (OA) is a common degenerative joint disease characterized by chondrocyte dysfunction. In this study, we explored the function and mechanism of ubiquitin‐specific protease 7 (USP7) in chondrocyte ferroptosis in OA. The USP7, TRPV1, collagen II, and GPX4 levels in knee joint tissue were detected using immunohistochemistry ...
Jun Li, Ding Chen, Wei‐Ye Zhong
wiley   +1 more source

Extracellular Vesicle‐Mediated Communication Between Anterior Cruciate Ligament and Bone Marrow Cells Modulates Hamstring Tenocyte Behavior and Apoptosis

open access: yesThe Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Following anterior cruciate ligament (ACL) reconstruction, enhancing hamstring tenocyte activity and minimizing apoptosis are critical for preventing graft failure and promoting ligamentization. This study investigated the therapeutic potential of extracellular vesicles (EVs) derived from a coculture of ACL remnant cells and bone marrow ...
Hon‐Lok Lo   +5 more
wiley   +1 more source

Posterior tibial slope increases over time in patients undergoing revision ACL reconstruction: A long‐term radiographic follow‐up study

open access: yesKnee Surgery, Sports Traumatology, Arthroscopy, EarlyView.
Abstract Purpose Increased medial posterior tibial slope (PTS) is recognized as a significant risk factor for anterior cruciate ligament reconstruction (ACL‐R) failure. This study investigated radiographic changes in medial PTS over time among skeletally mature individuals undergoing revision ACL‐R and identified associated factors contributing to PTS ...
Mahmut Enes Kayaalp   +9 more
wiley   +1 more source

Long‐term clinical and MRI outcomes of a polyurethane meniscal scaffold implantation for the treatment of partial meniscal deficiency: A minimum 10‐year follow‐up study

open access: yesKnee Surgery, Sports Traumatology, Arthroscopy, EarlyView.
Abstract Purpose To assess the clinical and magnetic resonance imaging (MRI) results after implantation of a polyurethane scaffold for chronic segmental meniscus deficiency following partial meniscectomy in a long‐term follow‐up. Study Design Level IV, retrospective case series. Methods Thirty‐two knees received arthroscopic implantation of an Actifit®
Vasileios S. Akrivos   +6 more
wiley   +1 more source

Isolated meniscal repair, medial meniscus repair and older age increase failure risk after all‐inside meniscal repair: A cohort study of 2264 patients

open access: yesKnee Surgery, Sports Traumatology, Arthroscopy, EarlyView.
Abstract Purpose To evaluate the overall failure rate and assess factors influencing the failure of modern all‐inside meniscal repair. Methods Patients who underwent all‐inside meniscal repair at Capio Artro Clinic, Stockholm, Sweden, from January 2015 to June 2022, were identified.
Christoffer von Essen   +4 more
wiley   +1 more source

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