Results 91 to 100 of about 71,899 (262)

User Requirement Study for a Virtual Research Environment

, 2005
This report is a documentation of a user requirement study for Collaborative Orthopaedics Research Environment (CORE) project. The study assesses the needs of users, who are researchers and clinicians working in a bone laboratory, for a Virtual Research ...
Wang, C., Gilbert, L., Wills, G. B., Sim, Y. W.   +3 more
core   +1 more source

Orthopaedics in day surgery

, 2009
Background: Day surgery is now well established worldwide, but is just being established in Africa. In this paper is examined the efficacy of day care surgery in Orthopaedics. Setting up of the units and types of units that are looked at. Objective: To
Mulimba, J A O
core  

Versatile Microgel Platform for Intervertebral Disc Degeneration Therapy: Targeting Pericyte‐Mediated Fibrosis and Protecting Nucleus Pulposus Cells

Advanced Science, EarlyView.
The engineered MMS@TRP microgel enables targeted, acid‐responsive delivery of a miR‐21 inhibitor to pericytes. It effectively suppresses disc fibrosis by inhibiting TGF‐β signaling while protecting nucleus pulposus cells via sustained, antioxidant tannic acid release.
Fei Ma, Zhen Zhao, Chuan Guo, Yuheng Liu, Yu Wang, Dengbo Yao, Weiqiang Lan, Dejun Zhong, Chen Fan, Yao He, Mei Zhang, Qingquan Kong, Yunfeng Lin   +12 more
wiley   +1 more source

Biomechanical analysis of the placement of fixation lag screw in different intertrochanteric hip fracture angles

Biosurface and Biotribology, 2019
The common surgical method for fracture fixation in the femoral neck and intertrochanteric region is the implantation a dynamic lag screw into the femoral head.
Alex C.T. Choh, Desmond Y.R. Chong
doaj   +1 more source

The role of magnets in orthodontics and dentofacial orthopaedics

, 2014
Magnets have been used in dentistry for many years. The force they deliver can be directed, and they can exert their force through mucosa and bone. There are various types of magnets used in the field of orthodontics and dentofacial orthopaedics, all ...
Gulshan K Singh, Pradeep Tandon, Sudhir Sharma, Dipti Shastri   +3 more
core   +1 more source

H4K12 Lactylation Regulates NDUFS7 to Drive Microglia Reverse Electron Transport in Spinal Cord Injury

Advanced Science, EarlyView.
Lactate accumulation after SCI promotes H4K12la lactylation, which upregulates NDUFS7, triggering mitochondrial RET and ROS, enforcing pro‐inflammatory microglial polarization. MM@mPTC, a biomimetic nanotherapeutic, degrades LDHA in activated microglia, reducing H4K12la lactylation and blocking RET, thus curbing ROS, fostering a reparative phenotype ...
Chenglong Hong, Zhichen Jiang, Zhouwei Wu, Chenyu Wu, Jiang Liu, Kaijie Guo, Yihui Liang, Shaobo Xu, Yuchen Jin, Yong Xiao, Lei Guo, Hui Xu, Sunren Sheng, Chenggui Wang   +13 more
wiley   +1 more source

Letter to the Editor on “Transpedicular Screw Placement Accuracy Using the O-Arm Versus Freehand Technique at a Single Institution. Global Spine Journal” by Crawford et al

Global Spine Journal, 2021
Bhavuk Garg MS(Orthopaedics), Nishank Mehta MS(Orthopaedics)   +1 more
doaj   +1 more source

Demineralised bone matrix in veterinary orthopaedics: A review

, 2010
SummaryDemineralised bone matrix (DBM) is commonly used in human orthopaedics as an allograft prepared from cortical bone. As such, there is a background of literature on the basic science, experimental animal studies and clinical human use of DBM ...
J. F. Innes, P. Myint
core   +1 more source

NCOA4 Accelerates Abdominal Aortic Aneurysm Formation by Regulating Macrophage Activation and Ferroptosis via STAT1–CH25H Axis

Advanced Science, EarlyView.
Under pathological stimulation, NCOA4 in macrophages interacts with STAT1 to promote CH25H transcription. The subsequent increase in 25‐HC production activates macrophages, triggers inflammatory responses and ferroptosis, and accelerates the progression of AAA.
Zhinan Wu, Yuxuan Qian, Wenyi Xu, Fei Liao, Xueliang Liu, Xiao Kuang, Guqing Luo, Xinjie He, Lixian Jiang, Song Ding   +9 more
wiley   +1 more source

S100A12 as a Shared Inflammatory Driver of Intervertebral Disc Degeneration and Osteoporosis: A Mendelian Randomization and Experimental Study

Journal of Inflammation Research
Zexin Wang,1,* Bin Chen,1,* Zhenchuan Liu,1 Yuanqiang Zhang,1 Leixiang Han2 1Department of Orthopedic Surgery, Qilu Hospital, Cheeloo College of Medicine, Shandong University, Jinan, Shandong, 250012, People’s Republic of China ...
Wang Z, Chen B, Liu Z, Zhang Y, Han L
doaj