Results 71 to 80 of about 250,488 (295)

RETREG1‐Mediated Reticulophagy is Essential for Dendritic Cell Maturation and Function in Sepsis

open access: yesAdvanced Science, EarlyView.
Reticulophagy regulator 1 (RETREG1) maintains dendritic cell (DC) maturation and function in early sepsis. Mechanistically, activating transcription factor 6 (ATF6) acts as a direct transcription factor regulating RETREG1 expression in response to sepsis‐induced endoplasmic reticulum (ER) stress.
Ren‐Qi Yao   +28 more
wiley   +1 more source

A 2-Year Outcomes and Complications of Various Techniques of Lumbar Discectomy: A Multicentric Prospective Study

open access: yesGlobal Spine Journal
Study Design Prospective Study. Objectives There are numerous techniques for performing lumbar discectomy, each with its own rationale and stated benefits.
Praveen Goparaju MS (Orthopaedics), FISS   +16 more
doaj   +1 more source

A Giant Lipoma In The Hand - Report Of A Rare Case [PDF]

open access: yes, 2006
A 38 years old male patient presented with a large painless swelling in the right palm with ultrasound examination suggestive of fatty nature of the swelling MRI showing a well-circumscribed soft tissue swelling in the deep palmar space.
-, Dr. Shridhar   +4 more
core   +1 more source

Targeting the PGRN‐BMP Lysosomal Axis With NPs@PGRN Reverses Immunometabolic Dysfunction in Chronic Septic Arthritis

open access: yesAdvanced Science, EarlyView.
Chronic septic arthritis involves intracellular bacterial persistence and lipid‐immune crosstalk via the PGRN‐BMP lysosomal axis. A dual‐targeting nanoparticle system (NPs@PGRN) restores lysosomal bactericidal function, reduces bacterial burden, and reprograms macrophage immunity, offering a novel therapeutic strategy. ABSTRACT Chronic septic arthritis,
Congsun Li   +12 more
wiley   +1 more source

Amputation in emergency situations: indications, techniques and Médecins Sans Frontières France's experience in Haiti [PDF]

open access: yes, 2012
PURPOSE: The decision to amputate is always difficult but becomes even harder in emergency situations, which usually present extra complicating factors.
D Pukljak   +4 more
core   +2 more sources

Radical‐Mediated, Substrate‐Independent Fabrication of Hybrid Solid–Hydrogel Materials With Tunable Crosslinking: An Initiator‐ and Crosslinker‐Free Approach

open access: yesAdvanced Science, EarlyView.
This work introduces a substrate‐independent, reagent‐free plasma strategy that forms radical‐rich interlayers for covalent hydrogel attachment without initiators or crosslinkers. The long‐lived radicals drive in situ gelation, creating robust, cytocompatible hybrid solid–hydrogel constructs across diverse substrates.
Ghazal Shineh   +14 more
wiley   +1 more source

Visualization of Endosomal Escape of Intracellularly Delivered Protein With Unexpected Photochemical Internalization of Trypan Blue

open access: yesAdvanced Science, EarlyView.
TB, a conventional cell viability dye, acts as both a fluorescence modulator (quenching GFP fluorescence upon protein binding and recovering it upon release) and a photosensitizer that triggers endosomal escape via photochemical internalization (PCI) under 590 nm light.
Zhongqi Yao   +4 more
wiley   +1 more source

The Women in ORTHopaedics Program Offers Early Exposure to Orthopaedic Surgery for Young Women. A Pre- and Post-Event Survey Comparison

open access: yesJournal of the Pediatric Orthopaedic Society of North America
Background: In recent years, the medical field has made significant progress toward promoting gender equality. Despite this progress, orthopaaedic surgery remains the least diverse specialty among other surgical specialties.
Marianna Hsu, BSc candidate   +3 more
doaj   +1 more source

Prediction of Early Periprosthetic Joint Infection After Total Hip Arthroplasty

open access: yesClinical Epidemiology, 2022
Erik Bülow,1,2 Ute Hahn,3,4 Ina Trolle Andersen,3 Ola Rolfson,1,2 Alma B Pedersen,3,5 Nils P Hailer6 1The Swedish Arthroplasty Register, Centre of Registers Västra Götaland, Gothenburg, Sweden; 2Department of Orthopaedics, Institute of ...
Bülow E   +5 more
doaj  

GPCRs in CAR‐T Cell Immunotherapy: Expanding the Target Landscape and Enhancing Therapeutic Efficacy

open access: yesAdvanced Science, EarlyView.
Chimeric antigen receptor T cell therapy faces dual challenges of target scarcity and an immunosuppressive microenvironment in solid tumors. This review highlights how G protein‐coupled receptors can serve as both novel targets to expand the therapeutic scope and functional modules to enhance CAR‐T cell efficacy.
Zhuoqun Liu   +11 more
wiley   +1 more source

Home - About - Disclaimer - Privacy