Results 71 to 80 of about 71,899 (262)

Single‐Nucleus Atlas of Spinal Sarcopenia Patients Reveals Disruption of Quiescent and Regenerative Satellite Cell Niches in Fatty‐Infiltrated Muscle

Advanced Science, EarlyView.
Mechanisms of Fatty Infiltration and Muscle Degeneration. Clinical metadata identified intramuscular fat accumulation as an independent driver of muscle mass decline. Single‐nucleus RNA sequencing of spinal sarcopenia muscle revealed adipogenic reprogramming of fibro‐adipogenic progenitors, satellite‐cell niche disruption, and elevated levels of the ...
Wenkai Wu, Renxian Wang, Dingding Wang, Quanzhong Ren, Ling Wang, Fangfang Duan, Guihe Yang, Ruixuan Yu, Yi Wang, Yingyu Zhang, Zetong Zang, Chuqi Li, Weijia Liu, Wenshuang Zhang, Yi Yuan, Zitong Cheng, Xiaoguang Cheng, Junbo Liang, Yajun Liu   +18 more
wiley   +1 more source

Patients with Clinically Suspected but Unproven Hip Fractures, Who Require Cross-Sectional Imaging, Are Best Initially Admitted under Geriatrician-Led Care—A Retrospective Review

Geriatrics, 2018
Patients with suspected hip fractures who require further imaging to confirm or disprove the diagnosis may be admitted to orthopaedic or medical departments. We aim to provide evidence regarding the appropriate admission pathway for such patients.
Hamish Macdonald, Niraj Vetharajan, Peter Kempshall   +2 more
doaj   +1 more source

Gut Microbiota‐Derived Indole‐3‐Propionic Acid Alleviates Diabetic Osteoporosis Through Nrf2‐Mediated Ferroptosis Suppression

Advanced Science, EarlyView.
Diabetes‐associated dysbiosis is accompanied by reduced Clostridium abundance, impaired microbial tryptophan metabolism, and lower circulating indole‐3‐propionic acid (IPA). Exogenous IPA improves trabecular microarchitecture and bone formation and restores Nrf2‐associated antioxidant signaling in bone marrow mesenchymal stem cells, limiting iron ...
Jinwu Bai, Qinyong You, Gao Si, Daole Hu, Ao Sun, Shilong Su, Ruideng Wang, Jixing Fan, Shan Gao, Tengjiao Zhu, Chun‐Li Song, Fang Zhou, Yang Lv   +12 more
wiley   +1 more source

Lives and limbs : re-membering Robert Jones : a biography [PDF]

, 2011
This is a biography of Robert Jones, 1857-1933. He was a surgeon, and is credited with bringing orthopaedics from its quack past into its scientific present. This work explores Jones’ life and times, and examines whether he is entitled to the epithet ‘
Bonetti (née Whiteley), Joanna
core   +2 more sources

CAD, CAE and rapid prototyping methods applied in long bones orthopaedics [PDF]

FME Transactions, 2019
The paper presents some methods used to analyze human bone joints. First, there were defined the 'hard' parts as the main bone components and 'soft' parts as ligaments or menisci using CT images.
Popa Dragos-Laurentiu, Buciu G., Calin D.C., Popkonstantinović B., Poenaru F.   +4 more
doaj  

Development of Orthopaedics in Kenya

, 2007
It is difficult to say at what point Orthopaedics in Kenya broke away from general surgery. All over the world, orthopaedics has developed as an off shoot of general surgery. There are various forms of practice of orthopaedics i.e.
Mulimba, J A O
core  

Acid‐Responsive Nanobot‐Integrated Core‐Shell Microneedles Reprogram the Degenerative Annulus Fibrosus Microenvironment Through Epigenetic Suppression of Ferroptosis

Advanced Science, EarlyView.
An acid‐responsive core‐shell microneedle system normalizes the degenerative annulus fibrosus microenvironment by consuming pathological H+, generating O2, and providing NIR‐amplified redox buffering. Mechanistically, it epigenetically suppresses ferroptosis via DNMT3A‐dependent methylation of the ATF3 promoter, relieving ATF3‐mediated repression of ...
Lu Tan, Yan Zheng, Yue Lan, Zhuo Cheng, Siya Wang, Changqing Li, Yanqiu Wang, Minghan Liu   +7 more
wiley   +1 more source

Supplementum 269: Abstracts of the 83th annual meeting of swiss orthopaedics

Swiss Medical Weekly, 2023
swiss orthopaedics
doaj   +1 more source

The Impact of Attention-Deficit/Hyperactivity Disorder on Postoperative Orthopedic Complications in Total Shoulder Arthroplasty: A Retrospective Cohort Study

The Hive
Background: Attention-deficit/hyperactivity disorder (ADHD) is a prevalent neurodevelopmental disorder characterized by impulsiveness and challenges with adherence, potentially affecting surgical outcomes.
Seyedeh Zahra Mousavi, Mahdieh Saeidi, Henry M. Fox, Sasidhar Gunturu , Umasuthan Srikumaran   +4 more
doaj   +1 more source

The Contributions of Kenelm Hutchinson Digby to Orthopaedics in Hong Kong Part 2

Journal of Orthopaedics, Trauma and Rehabilitation, 2016
As the first professor of surgery in Hong Kong, Kenelm Hutchinson Digby had the tremendous task of building a new clinical department in the infant University of Hong Kong from scratch.
Kuo-tai Louis Fu
doaj   +1 more source