Results 121 to 130 of about 95,083 (274)
High‐Resolution Stereolithography of Amorphous, Dense and Mechanically Stable Bioactive Glass
Advanced Materials Technologies, EarlyView.Porous scaffolds made of bioactive glass are of great interest for bone tissue engineering. The geometry and resolution of the scaffold is impacting its bioactive and mechanical performance. Utilizing stereolithographic 3D printing of bioactive glass, human cancellous bone scaffolds, and other structures are fabricated with features as small as 77 µm ...
Leonhard Hambitzer +8 more
wiley +1 more source
Advanced Science, EarlyView.This study defines the structure, mechanics, and mechanobiology of the fibrocartilage pericellular matrix (PCM) using the murine meniscus, showing how collagen V deficiency alters PCM properties and disrupts cell mechanosensitive signaling. Findings emphasize the critical role of PCM in fibrocartilage mechanobiology and suggest targeting it can enhance
Chao Wang +13 more
wiley +1 more source
Advanced Science, EarlyView.Glucocorticoid‐induced osteoporosis (GIOP) triggers osteocyte ferroptosis via SLC7A11 degradation. PSMD14 stabilizes SLC7A11 by counteracting glucocorticoid‐driven ubiquitination, preserving cystine uptake and glutathione synthesis. AAV‐mediated PSMD14 delivery or its agonist Pantethine rescues osteocyte survival and bone loss in GIOP mice.
Yifeng Shi +20 more
wiley +1 more source
Augmented reality guidance improves accuracy of orthopedic drilling procedures
Scientific ReportsIn several orthopedic procedures, the accurate use of surgical power tools is critical to avoid damage to surrounding tissues. As such, various guidance techniques and safety measures were developed.
Frederick Van Gestel +8 more
doaj +1 more source
Advanced Science, EarlyView.Activation of HTR2B suppresses osteosarcoma progression through the STAT1‐NLRP3 inflammasome pathway and promotes OASL1+ Macrophage production to enhance anti‐tumor immunity. Abstract Osteosarcoma is a primary malignant bone tumor originating from mesenchymal tissue, and associated with poor prognosis.
Zhen Huang +7 more
wiley +1 more source
Advanced Science, EarlyView.Oxygen‐releasing immunomodulatory microspheres are used to construct conformal bone organoid units that enhance osteogenesis, angiogenesis, and immune regulation. By integrating BMSCs, macrophages, and CaO₂‐HAp into a SilMA‐based hydrogel platform, this strategy provides sustained oxygen supply and anti‐inflammatory microenvironments, leading to ...
Anfu Deng +12 more
wiley +1 more source
Advanced Science, EarlyView.This work identifies fine‐tuning the expression of PIEZO1 as a critical molecular mechanism underlying the treatment of myocardial infarction by mechanically adapted cardiac patches, which can support the clinical translation of cardiac patch devices.
Yuwen Lu +18 more
wiley +1 more source