Results 71 to 80 of about 250,574 (293)

Comparison of Visual Analog Pain Score Reported to Physician vs Nurse in Nonoperatively Treated Foot and Ankle Patients [PDF]

open access: yes, 2019
Background: Patient reported outcome measures (PROMs) are taking a more prominent role in Orthopedics as health care seeks to define treatment outcomes. The Visual Analogue Scale (VAS) is considered a reliable measure of acute pain.
Dewar, BS, Cuyler   +4 more
core   +1 more source

Vm–MSI: a Vancomycin–Antimicrobial Peptide Conjugate Combating Resistant Bacteria and Broadening the Antimicrobial Spectrum

open access: yesAdvanced Science, EarlyView.
A series of vancomycin‐antimicrobial peptide conjugates is synthesized and evaluated to identify the optimal combination. Vm‐MSI, selected from multiple candidates, exhibited potent activity against vancomycin‐resistant and Gram‐negative bacteria by disrupting membranes and inducing oxidative stress, thereby expanding vancomycin's antibacterial ...
Shuangyu Li   +7 more
wiley   +1 more source

A Guide to Prescribing Sufficient Post Surgical Quantities of Opiate Pain Medications [PDF]

open access: yes, 2019
Purpose: To examine opiate pain medication prescription and consumption after surgical procedures at VCU Medical ...
Pflugrath, Adam
core   +1 more source

Targeted Inhibition of CD74+ Macrophages by Luteolin via CEBPB/P65 Signaling Ameliorates Osteoarthritis Progression

open access: yesAdvanced Science, EarlyView.
This study identifies CD74⁺ macrophages as key drivers of synovial inflammation in osteoarthritis (OA). The flavonoid luteolin is predicted to inhibit this pathway by blocking Nuclear Factor Kappa‐light‐chain‐enhancer of Activated B cells (NF‐κB) signaling. To enhance delivery, a targeted nanoplatform (MDSPL) is developed.
Rui Peng   +15 more
wiley   +1 more source

Identification of Potential Targets for EGFR-Regulated Nucleus Pulposus Degeneration Using Single-Cell RNA Sequencing and Machine Learning

open access: yesJournal of Inflammation Research
Xiaoyao Peng,1,* Yi Wang,2,* Yangyang Chen,3 Yuxiang Hu,1 Fashuai Wu,1 Lu Zhang,4 Weihua Xu,1 Yulong Wei1 1Department of Orthopaedics, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei ...
Peng X   +7 more
doaj  

USE OF LASER IN MEDICINE, POTENTIAL OF USING LASER ERADIATION IN TRAUMATOLOGY AND ORTHOPEDICS

open access: yesŽurnal Grodnenskogo Gosudarstvennogo Medicinskogo Universiteta, 2018
The aim of the present article is to analyze foreign and native literature sources devoted to the effect of laser eradiation on biological tissue. The paper describes the potential of using laser in traumatology and orthopedics, which can optimize and ...
Khotim O. A.   +2 more
doaj   +1 more source

Transient neurologic symptoms following spinal anesthesia with isobaric mepivacaine: A decade of experience at Toronto Western Hospital [PDF]

open access: yes, 2018
Background: Transient neurologic symptoms (TNSs) can be distressing for patients and providers following uneventful spinal anesthesia. Spinal mepivacaine may be less commonly associated with TNS than lidocaine; however, reported rates of TNS with ...
Abdallah, Faraj W.   +4 more
core   +2 more sources

Steap4 Promotes Senile Osteoporosis via Fe2+‐ROS/C/EBPβ Feedback‐Driven Ferroptosis and Adipogenesis in Senescent BMSCs

open access: yesAdvanced Science, EarlyView.
Senescent bone marrow mesenchymal stem cells (BMSCs) exhibit increased sensitivity to ferroptosis, a phenomenon associated with Steap4, a nicotinamide adenine dinucleotide phosphate hydrogen (NADPH)‐dependent metalloreductase that reduces Fe3+ to Fe2+.
Liangliang Wang   +9 more
wiley   +1 more source

Perineural Dexamethasone is More Efficient Than Perineural Dexmedetomidine in Prolonging Popliteal Sciatic and Saphenous Nerve Blocks: A Single-Center, Prospective, Double-Blinded, Randomized Controlled Trial

open access: yesLocal and Regional Anesthesia
Guiyu Lei,1 Lili Wu,1 Yue Yin,1 Shu Zhang,2 Guyan Wang1 1Department of Anesthesiology, Beijing Tongren Hospital, Capital Medical University, Beijing, 100730, People’s Republic of China; 2Center of Foot and Ankle Surgery, Beijing Tongren Hospital, Capital
Lei G, Wu L, Yin Y, Zhang S, Wang G
doaj  

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