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In Vivo and In Vitro Antidiabetic Efficacy of Aqueous and Methanolic Extracts of Orthosiphon Stamineus Benth [PDF]

Pharmaceutics, 2023
Orthosiphon stamineus is a popular folk herb used to treat diabetes and some other disorders. Previous studies have shown that O. stamineus extracts were able to balance blood glucose levels in diabetic rat animal models.
Najlaá Bassalat, Sleman Kadan, Ziporà Tietel   +2 more
exaly   +4 more sources

Free Radical Scavenging, Antimicrobial and Immunomodulatory Activities of <em>Orthosiphon stamineus</em> [PDF]

Molecules, 2012
<em>Orthosiphon stamineus </em>is considered an important traditional folk medicine. In this study ethanol and aqueous extracts of <em>O.
Nabil S. Harmal, Hamid A. Hadi, Suhailah W. Qader, Mohammed A. Alshawsh, Salmah Ismail, Zahra A. Amin, Mahmood A. Abdulla   +6 more
doaj   +5 more sources

Mechanism of action of Orthosiphon stamineus against non-alcoholic fatty liver disease: Insights from systems pharmacology and molecular docking approaches [PDF]

Saudi Pharmaceutical Journal, 2022
Non-alcoholic fatty liver disease (NAFLD) is one of the most common complications of a metabolic syndrome caused by excessive accumulation of fat in the liver.
Salah Abdulrazak Alshehade, Raghdaa Hamdan Al Zarzour, Vikneswaran Murugaiyah, Sharoen Yu Ming Lim, Huda Ghaleb El-Refae, Mohammed Abdullah Alshawsh   +5 more
doaj   +2 more sources

A Systematic Review of Orthosiphon stamineus Benth. in the Treatment of Diabetes and Its Complications [PDF]

Molecules, 2022
(1) Background: Orthosiphon stamineus Benth. is a traditional medicine used in the treatment of diabetes and chronic renal failure in southern China, Malaysia, and Thailand.
Qirou Wang, Jia Wang, Nannan Li, Junyu Liu, Jingna Zhou, Pengwei Zhuang, Haixia Chen   +6 more
doaj   +2 more sources

Polymolecular botanical drug of Orthosiphon stamineus extract (C5OSEW5050ESA) as a complementary therapy to overcome gemcitabine resistance in pancreatic cancer cells [PDF]

Journal of Traditional and Complementary Medicine, 2023
Background and aim: Gemcitabine remains the cornerstone of pancreatic cancer treatment, despite exhibiting a modest effect on patient survival due to the development of drug resistance.
Ashwaq H.S. Yehya, Muhammad Asif, Amin M.S. Abdul Majid, Chern E. Oon   +3 more
doaj   +2 more sources

RETRACTION: Antiapoptotic and Antioxidant Properties of <i>Orthosiphon stamineus</i> Benth (Cat's Whiskers): Intervention in the Bcl-2-Mediated Apoptotic Pathway. [PDF]

Evid Based Complement Alternat Med
Evidence-Based Complementary and Alternative Medicine, Volume 2025, Issue 1, 2025.
And Alternative Medicine EC.
europepmc   +2 more sources

Analysis of the chemical constituents and their metabolites in Orthosiphon stamineus Benth. via UHPLC-Q exactive orbitrap-HRMS and AFADESI-MSI techniques. [PDF]

PLoS ONE
BackgroundKnown for its strong diuretic properties, the perennial herbaceous plant Orthosiphon stamineus Benth. is believed to preserve the kidney disease. This study compared the boiling water extract with powdered Orthosiphon stamineus Benth.
Jianting Ouyang, Danyao Lin, Xuesheng Chen, Yimeng Li, Qin Liu, Delun Li, Haohao Quan, Xinwen Fu, Qiaoru Wu, Xiaowan Wang, Shouhai Wu, Chuang Li, Yi Feng, Wei Mao   +13 more
doaj   +2 more sources

Orthosiphon stamineus Proteins Alleviate Pentylenetetrazol-Induced Seizures in Zebrafish. [PDF]

Biomedicines, 2020
The anticonvulsive potential of proteins extracted from Orthosiphon stamineus leaves (OSLP) has never been elucidated in zebrafish (Danio rerio). This study thus aims to elucidate the anticonvulsive potential of OSLP in pentylenetetrazol (PTZ)-induced seizure model.
Chung YS, Choo BKM, Ahmed PK, Othman I, Shaikh MF.   +4 more
europepmc   +5 more sources

An in vitro study of orthosiphon stamineus (misai kucing) standardized water extract as a chemolytic agent in urolithiasis

Journal of Pharmacy and Bioallied Sciences, 2021
Background: Orthosiphon stamineus was reported to have diuretic effects in experimental rats, and this leads to inhibition of kidney stones through the abundant levels of minerals and flavonoids in it.
Muhammad Bala Ambursa, Mohd Nor Gohar Rahman, Siti Amrah Sulaiman, Andee Dzulkarnaen Zakaria, Mohamed Ashraf Mohamed Daud, Zaidi Zakaria, Zalina Zahari, Michael Pak-Kai Wong   +7 more
doaj   +2 more sources

Toxicological studies of Orthosiphon stamineus (Misai Kucing) standardized ethanol extract in combination with gemcitabine in athymic nude mice model [PDF]

Journal of Advanced Research, 2019
Pancreatic cancer has the highest mortality rate among cancers due to its aggressive biology and lack of effective treatment. Gemcitabine, the first line anticancer drug has reduced efficacy due to acquired resistance.
Ashwaq H.S. Yehya, Muhammad Asif, Gurjeet Kaur, Loiy E.A. Hassan, Fouad S.R. Al-Suede, Amin M.S. Abdul Majid, Chern E. Oon   +6 more
doaj   +2 more sources