The Health Gym: Synthetic Health-Related Datasets for the Development of Reinforcement Learning Algorithms [PDF]
In recent years, the machine learning research community has benefited tremendously from the availability of openly accessible benchmark datasets. Clinical data are usually not openly available due to their highly confidential nature. This has hampered the development of reproducible and generalisable machine learning applications in health care.
arxiv
Being Prodromal: Current Criteria in the Context of Isolated REM Sleep Behavior Disorder
ABSTRACT Background Isolated REM sleep behavior disorder (iRBD) indicates an early α‐synucleinopathy with approximately 90% of individuals pheno‐converting to Parkinson's disease (PD), dementia with Lewy bodies (DLB), or multiple system atrophy (MSA). Recently, prodromal disease definitions (pPD, pDLB, pMSA) have been introduced.
Anja Ophey+5 more
wiley +1 more source
Autonomic Dysfunction in Acromegaly: A Case Report [PDF]
Orthostatic hypotension commonly presents in patients with chronic illnesses like hypertension, diabetes mellitus, chronic kidney disease and LV dysfunction.
Kotwal, Narendra+3 more
core +1 more source
Postsynaptic α1-Adrenergic vasoconstriction is impaired in young patients with vasovagal syncope and is corrected by nitric oxide synthase inhibition [PDF]
BACKGROUND: Syncope is a sudden transient loss of consciousness and postural tone with spontaneous recovery; the most common form is vasovagal syncope (VVS).
Medow, MS+6 more
core +1 more source
Attention mechanisms for physiological signal deep learning: which attention should we take? [PDF]
Attention mechanisms are widely used to dramatically improve deep learning model performance in various fields. However, their general ability to improve the performance of physiological signal deep learning model is immature. In this study, we experimentally analyze four attention mechanisms (e.g., squeeze-and-excitation, non-local, convolutional ...
arxiv
Orthostatic Hypotension in Parkinson's Disease [PDF]
Abstract: Orthostatic hypotension (OH) is a frequent non-motor symptom in Parkinson’s Disease (PD) affecting between 22.9 and 38.4% of patients. OH is related in PD to increased risk of falls and possibly to cognitive dysfunction and increased mortality. These data emphasizes the importance of its prompt recognition and treatment.
María Verónica Rey+5 more
openaire +2 more sources
Abstract Background The lived experience of Parkinson's disease (PD) includes motor and non‐motor symptoms. There is a need to capture the earliest patient experiences in a sensitive and reliable manner for the successful development of interventions that may delay clinical progression in PD.
Joseph Saade+3 more
wiley +1 more source
Hemodynamic orthostatic dizziness/vertigo: diagnostic criteria [PDF]
This paper presents the diagnostic criteria for hemodynamic orthostatic dizziness/vertigo to be included in the International Classification of Vestibular Disorders (ICVD).
Bisdorff, A+7 more
core +1 more source
The Gut‐Brain Axis in Parkinson disease: Emerging Concepts and Therapeutic Implications
Abstract Background The gut‐brain axis, i.e. the bidirectional communication system between the gut and the brain, has become of central importance in Parkinson disease (PD) research over the past 20 years. Aims We aimed to describe the milestones of the gut‐brain axis research in PD and the development of theories proposing the involvement of the ...
Elisa Menozzi+2 more
wiley +1 more source
Orthostatic Cerebral Hypoperfusion Syndrome (OCHOS)
Objective: Orthostatic dizziness without orthostatic hypotension is common but underlying pathophysiology is poorly understood. This study describes orthostatic cerebral hypoperfusion syndrome (OCHOS). OCHOS is defined by: 1) Abnormal orthostatic drop of
Peter eNovak
doaj +1 more source