Results 91 to 100 of about 160,818 (303)
ChemistryOpen, EarlyView.Structure‐based virtual screening of PubChem compounds identifies two novel epalrestat and ranirestat‐like inhibitors with improved affinity and pharmacokinetic profiles targeting aldose reductase. Molecular docking, ADMET filtering, and 500‐ns molecular dynamics simulations confirm the stability and interaction specificity of the candidates ...
Mohd Shahnawaz Khan +3 more
wiley +1 more source
Decreased Noradrenaline (Norepinephrine) Synthesis in Neurogenic Orthostatic Hypotension [PDF]
, 1968 McC. Goodall, W. R. Harlan, Harold Alton
openalex +1 more source
Orthostatic hypotension and cardiovascular risk
Kardiologia Polska, 2019 Orthostatic hypotension (OH) is a cardinal sign of cardiovascular (CV) autonomic dysfunction as a result of autonomic nervous system failure to control the postural hemodynamic homeostasis. The proportion of individuals with OH increases with aging and chronic conditions, such as neurodegenerative diseases, hypertension, heart failure, diabetes, renal ...
Fabrizio Ricci +4 more
openaire +6 more sources
Sensory Neuroscience, EarlyView.ABSTRACT Sensory neuron disorders, such as peripheral neuropathies and trigeminal neuralgia, cause chronic pain and sensory dysfunction; however, regenerative treatments are limited. Human pluripotent stem cells (hPSCs) provide a powerful platform to model these diseases by generating functional sensory neuron subtypes, including nociceptors and ...
Pushpanathan Muthuirulan +3 more
wiley +1 more source
Orthostatic hypotension and the Holmes-Adie syndrome: A study of two patients with afferent baroreceptor block [PDF]
, 1971 Ralph H. Johnson +2 more
openalex +1 more source
The potential role of arteriolar vasodilator responsiveness in orthostatic intolerance [PDF]
, 2013 Due to the character of the original source materials and the nature of batch digitization, quality control issues may be present in this document. Please report any quality issues you encounter to digital@library.tamu.edu, referencing the URI of the ...
McCurdy, Matthew R
core
Serious outcomes among emergency department patients with presyncope: A systematic review
Academic Emergency Medicine, EarlyView.Abstract Background Syncope is transient loss of consciousness, and in presyncope, patients experience same prodromal symptoms without losing consciousness. While studies have extensively reported the risk of serious outcome among emergency department (ED) syncope, the outcome for patients with presyncope and their management are not well studied.
Hadi Mirfazaelian +4 more
wiley +1 more source
Orthostatic hypotension and the renin-angiotensin system in paraplegia [PDF]
, 1971 Ralph H. Johnson, D M Park, H L Frankel
openalex +1 more source
BMC Neurology, 2018 BackgroundNeurogenic orthostatic hypotension (nOH) results from impaired vasoconstriction due to dysfunction of the autonomic nervous system and is commonly associated with Parkinson disease (PD), multiple system atrophy (MSA), and pure autonomic failure.
D. Claassen +3 more
semanticscholar +1 more source
Anaesthesia, EarlyView.Summary Introduction Several regional anaesthesia techniques have been used in the peri‐operative pain management of patients who undergo primary elective total hip arthroplasty. The erector spinae plane, pericapsular nerve group and lateral femoral cutaneous nerve blocks offer motor‐sparing analgesia of the hip region but target different areas.
Francesca Buffoli +10 more
wiley +1 more source