Results 61 to 70 of about 9,964 (184)

Isometric training at longer muscle–tendon complex lengths: A potential countermeasure to impaired neuro‐muscle–tendon function during space travel

Experimental Physiology, EarlyView.
Abstract Manned space exploration to distant destinations, including Mars, continues to be an aspiration of humankind. Space travel does, however, present many challenges to the body, amongst which adaptation to microgravity is perhaps the largest. For instance, both short and long manned spaceflight missions have shown substantial deleterious effects ...
Gerard McMahon, Andy Sanderson, Hans Degens   +2 more
wiley   +1 more source

Cerebrovascular pulsatility following long duration spaceflight is associated with changes in pulse pressure and carotid artery stiffness

Experimental Physiology, EarlyView.
Abstract Central artery stiffening increases the haemodynamic pulsations transmitted downstream towards target organs, including the brain. While recent evidence suggests that long duration spaceflight is associated with reduced common carotid artery (CCA) distensibility, cerebrovascular pulsatility has not been extensively characterized in astronauts.
Roxanne Fournier, Danielle K. Greaves, J. Kevin Shoemaker, Philippe Arbeille, Richard L. Hughson, Andrew D. Robertson   +5 more
wiley   +1 more source

Neurohumoral mechanisms associated with orthostasis: Reaffirmation of the significant contribution of the heart rate response

Frontiers in Physiology, 2014
The inability to compensate for acute central hypovolemia underlies the clinical development of orthostatic hypotension and instability (e.g., syncope). Although neuro-humoral control of both cardiac output and peripheral vascular resistance contributes ...
Victor A Convertino
doaj   +1 more source

Deconditioning does not explain orthostatic intolerance in ME/CFS (myalgic encephalomyelitis/chronic fatigue syndrome)

Journal of Translational Medicine, 2021
Background Orthostatic intolerance (OI) is a frequent finding in individuals with myalgic encephalomyelitis /chronic fatigue syndrome (ME/CFS). Published studies have proposed that deconditioning is an important pathophysiological mechanism in various ...
C. (Linda) M. C. van Campen, Peter C. Rowe, Frans C. Visser   +2 more
doaj   +1 more source

Classical and Delayed Orthostatic Hypotension in Patients With Unexplained Syncope and Severe Orthostatic Intolerance

Frontiers in Cardiovascular Medicine, 2020
Background: Orthostatic hypotension (OH) is a major sign of cardiovascular autonomic failure leading to orthostatic intolerance and syncope. Orthostatic hypotension is traditionally divided into classical OH (cOH) and delayed OH (dOH), but the ...
Parisa Torabi, Parisa Torabi, Fabrizio Ricci, Fabrizio Ricci, Viktor Hamrefors, Viktor Hamrefors, Richard Sutton, Richard Sutton, Artur Fedorowski, Artur Fedorowski   +9 more
doaj   +1 more source

Individuals with persisting post‐concussion symptoms with physiological subtype demonstrate altered cardiovascular and autonomic responses to face cooling

Experimental Physiology, EarlyView.
Abstract Individuals with persisting post‐concussion symptoms with physiological subtype (PPCS‐P) demonstrate exercise intolerance due to exacerbation of concussion‐like symptoms during incremental exercise. We tested the hypothesis that individuals with PPCS‐P (n = 12) would have a blunted cardiac autonomic response to face cooling compared to healthy
Phillip J. Wallace, Steve Lidstone, Josh G. Nowlan, Johnathan Ljubanovich, Brandon J. McKinlay, Stephen A. Klassen, Stephen S. Cheung   +6 more
wiley   +1 more source

Time‐course analysis of cerebral circulation and cardiorespiratory responses to acute central blood volume reduction in healthy young males

Experimental Physiology, EarlyView.
Abstract Central blood volume (CBV) reduction challenges circulatory and respiratory homeostasis, particularly during the initial compensatory phase (0–2 min), when rapid physiological adaptations occur. In this study, we examined dynamic cardiorespiratory responses to CBV reduction using lower‐body negative pressure (LBNP) in 11 healthy young males ...
Marina Feeley, Tomoki Watada, Go Ito, Ai Shimada, Toru Sawai, Hideomi Nakata, Shingo Otsuki, Tadayoshi Miyamoto   +7 more
wiley   +1 more source

The effects of bed rest on cardiometabolic health: A systematic review and meta‐analysis

Experimental Physiology, EarlyView.
Abstract Horizontal bed rest (HBR) and head‐down tilt (HDT) are models of physical inactivity. In this systematic review and meta‐analysis, we aimed to quantify changes in cardiometabolic outcomes during HBR and HDT in healthy adults. Following the PRISMA guidelines, we searched PubMed, Scopus, Web of Science and Cochrane Library until 1 October 2025 ...
Konstantinos Prokopidis, Tyler Daubrah‐Scott, Alyssa Varanoske, Jordi Morwani‐Mangnani, David D. Church, Colleen S. Deane, Bethan E. Phillips, Emily J. Arentson‐Lantz   +7 more
wiley   +1 more source

Sex differences in dynamic cerebral autoregulation responses to resistance and endurance training in humans

Experimental Physiology, EarlyView.
Abstract Exercise maintains brain health and reduces the risk of cerebrovascular diseases, such as stroke and dementia. The benefits of different ‘modalities’ of exercise on male and female cerebral autoregulation are unclear. In this study, we compared adaptations in dynamic cerebral autoregulation (dCA) during spontaneous and forced oscillations in ...
Hannah J. Thomas, Channa E. Marsh, Leanne Lester, Louise H. Naylor, Kurt J. Smith, Daniel J. Green   +5 more
wiley   +1 more source

Heart rate variability analysis in postural orthostatic tachycardia syndrome: a case report

Heart International, 2006
The authors present a case of 36 year old male patient with idiopathic postural orthostatic tachycardia syndrome (POTS) diagnosed during head-up tilt testing.
Raffaele Calabrò, Lucio Santangelo, Cristina Savarese, Carolina Pagano, Ernesto Ammendola, Ilaria De Crescenzo, Vincenzo Russo   +6 more
doaj   +1 more source