Results 61 to 70 of about 15,908 (215)
Introduction: Orthostatic intolerance is common among individuals with myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS). In some ME/CFS case definitions, orthostatic intolerance is considered a core feature of the disorder.
C. (Linda) M. C. van Campen +2 more
doaj +1 more source
Abstract Manned space exploration to distant destinations, including Mars, continues to be an aspiration of humankind. Space travel does, however, present many challenges to the body, amongst which adaptation to microgravity is perhaps the largest. For instance, both short and long manned spaceflight missions have shown substantial deleterious effects ...
Gerard McMahon +2 more
wiley +1 more source
Abstract Central artery stiffening increases the haemodynamic pulsations transmitted downstream towards target organs, including the brain. While recent evidence suggests that long duration spaceflight is associated with reduced common carotid artery (CCA) distensibility, cerebrovascular pulsatility has not been extensively characterized in astronauts.
Roxanne Fournier +5 more
wiley +1 more source
Background: Clinical presentation varies in children with Orthostatic Intolerance. This study aimed to evaluate the epidemiological and clinical characteristics of pediatric patients with orthostatic intolerance (OI) and positive head-up tilt test (HUTT).
Anand Gourishankar +5 more
doaj +1 more source
Structural and Functional Small Fiber Abnormalities in the Neuropathic Postural Tachycardia Syndrome [PDF]
Objective: To define the neuropathology, clinical phenotype, autonomic physiology and differentiating features in individuals with neuropathic and non-neuropathic postural tachycardia syndrome (POTS).
Benson, Adam +4 more
core +2 more sources
Chronic Orthostatic Intolerance [PDF]
Chronic orthostatic intolerance (COI, also known as postural orthostatic tachycardia syndrome) is a disorder that most frequently affects young women (female-to-male ratio, 4:1).1 Presenting symptoms include lightheadedness, palpitations, fatigue, blurred vision, dizziness, exercise intolerance, chest discomfort, cognitive impairment, and occasionally ...
K, Narkiewicz, V K, Somers
openaire +2 more sources
Abstract Individuals with persisting post‐concussion symptoms with physiological subtype (PPCS‐P) demonstrate exercise intolerance due to exacerbation of concussion‐like symptoms during incremental exercise. We tested the hypothesis that individuals with PPCS‐P (n = 12) would have a blunted cardiac autonomic response to face cooling compared to healthy
Phillip J. Wallace +6 more
wiley +1 more source
The inability to compensate for acute central hypovolemia underlies the clinical development of orthostatic hypotension and instability (e.g., syncope). Although neuro-humoral control of both cardiac output and peripheral vascular resistance contributes ...
Victor A Convertino
doaj +1 more source
Abstract Central blood volume (CBV) reduction challenges circulatory and respiratory homeostasis, particularly during the initial compensatory phase (0–2 min), when rapid physiological adaptations occur. In this study, we examined dynamic cardiorespiratory responses to CBV reduction using lower‐body negative pressure (LBNP) in 11 healthy young males ...
Marina Feeley +7 more
wiley +1 more source
The effects of bed rest on cardiometabolic health: A systematic review and meta‐analysis
Abstract Horizontal bed rest (HBR) and head‐down tilt (HDT) are models of physical inactivity. In this systematic review and meta‐analysis, we aimed to quantify changes in cardiometabolic outcomes during HBR and HDT in healthy adults. Following the PRISMA guidelines, we searched PubMed, Scopus, Web of Science and Cochrane Library until 1 October 2025 ...
Konstantinos Prokopidis +7 more
wiley +1 more source

