Results 31 to 40 of about 33,871 (216)

Current standards in the diagnosis and treatment of oral squamous cell carcinoma – a multicenter analysis

GMS Interdisciplinary Plastic and Reconstructive Surgery DGPW, 2023
The German guideline for oral squamous cell carcinoma (OSCC) describes the recommended diagnosis and treatment procedures for OSCC and ensures the highest quality patient care.
Schreder, Karsten, Thiele, Oliver, Eckert, Alexander   +2 more
doaj   +1 more source

GM‐CSF Promotes Neutrophil PD‐L1 Expression Through the VEGFR‐2/STAT6/CSF2 Signaling Axis in Oral Squamous Cell Carcinoma

Advanced Science, EarlyView.
VEGFR‐2 signaling in OSCC activates Src–STAT6‐dependent CSF2 transcription, driving tumor‐derived GM‐CSF secretion. GM‐CSF programs neutrophils to express PD‐L1 through STAT5–mTOR/S6K signaling, suppressing cytotoxic CD8+ T cells. This pathway reveals a tumor–neutrophil immune checkpoint circuit that limits anti‐PD‐1 responsiveness in OSCC.
Fangxing Zhu, Yuanhe You, Yiyi Zhang, Yibin Dai, Xinyu Zhou, Yong Fu, Xi Lu, Yingying Huang, Zhihang Zhou, Ronghui Xia, Wutong Ju, Zhaoqi Yuan, Laiping Zhong, Tongchao Zhao   +13 more
wiley   +1 more source

Plasma Matrix Metalloproteinase-1 as a Prognostic Biomarker in Oral Cavity Squamous Cell Carcinoma

Cancer Management and Research, 2022
Tsung-You Tsai,1,* Huang-Kai Kao,2,3,* Yenlin Huang,4 Ya-Ting Chang,5 Chi-Kuang Young,1 Shao-Yu Hung,3 Yu-Sun Chang,5 Jau-Song Yu,1,5,6 Kai-Ping Chang1,2,5 1Department of Otolaryngology-Head and Neck Surgery, Chang Gung Memorial Hospital ...
Tsai TY, Kao HK, Huang Y, Chang YT, Young CK, Hung SY, Chang YS, Yu JS, Chang KP   +8 more
doaj  

The CS1 segment of fibronectin is involved in human OSCC pathogenesis by mediating OSCC cell spreading, migration, and invasion [PDF]

, 2010
Background The alternatively spliced V region or type III connecting segment III (IIICS) of fibronectin is important in early development, wound healing, and tumorigenesis, however, its role in oral cancer has not been fully investigated.
Pachiyappan Kamarajan, Kapila, Yvonne L, Kapila Yvonne L, D'Silva, Nisha J, Nisha J D'Silva, García-Pardo, Angeles, D'Silva Nisha J, Kamarajan Pachiyappan, Kapila, Yvonne, Kamarajan, Pachiyappan, D'Silva, Nisha J., Garcia-Pardo Angeles, Angeles Garcia-Pardo, Yvonne L Kapila   +13 more
core   +2 more sources

Restoration of m6A‐Modified circPSMB1 Suppresses Chordoma Progression and Enables Local Nanotherapeutic Intervention

Advanced Science, EarlyView.
An m6A‐modified circRNA, circPSMB1, is identified as a tumor suppressor in chordoma. METTL3‐dependent m6A promotes circPSMB1 interaction with HNRNPA2B1, limiting c‐MYC expression and malignant progression. An injectable HMnO2‐based nanohydrogel enables local circPSMB1 delivery and tumor microenvironment‐responsive therapy, offering a promising strategy
Yingchuang Tang, Liang Qiu, Xingbang Ruan, Yihan Shi, Ye Wang, Hanwen Li, Kai Zhang, Kangwu Chen   +7 more
wiley   +1 more source

Role of Ki-67, Cyclin D1, and p53 in Early Diagnosis and in the Prognosis of Oral Squamous Cell Carcinoma: A Cross-sectional Study Research Protocol [PDF]

Journal of Clinical and Diagnostic Research
Introduction: Oral Squamous Cell Carcinoma (OSCC) accounts for more than 90% of all oral cancers. It is among the top three cancers in India, along with cervical and breast cancer. Oral Epithelial Dysplasia (OED) represents a premalignant lesion that can
Khushi Soni, Keshav Hiwale
doaj   +1 more source

TPM1 staining scores in OSCC.

, 2017
TPM1 staining scores in OSCC.
Zhigang Yao (2254453), Hao Pan (173271), Yiping Li (139011), Yuehong Wang (791343), Long Li (6555), Xinna Bai (3738103), Liqun Gu (3738100), Binjie Liu (1717423), Qian Peng (74762), Baisheng Wang (730795), Zhangui Tang (730798)   +10 more
core   +1 more source

Biomimetic Scaffold‐Based 3D Models for Decoding Cancer Biology and Advancing Therapy

Advanced Science, EarlyView.
A timeline of the research history of 3D biomimetic scaffold materials and platforms. With advances in biomimetic materials and 3D scaffold technologies, their functional scope has expanded from mimicking basic physical and biochemical properties to increasingly replicating complex pathophysiological processes.
Haitao Zhao, Yuechen Han, Jie Li, Peng Luo, Lin Qi, Zhiwei Xia, Xiaosong Li, Quan Cheng, Chenshen Huang, Wantao Wu, Hao Zhang   +10 more
wiley   +1 more source

Circumventing AKT-Associated Radioresistance in Oral Cancer by Novel Nanoparticle-Encapsulated Capivasertib

Cells, 2020
Background: Development of radioresistance in oral squamous cell carcinoma (OSCC) remains a significant problem in cancer treatment, contributing to the lack of improvement in survival trends in recent decades.
Liwei Lang, Tiffany Lam, Alex Chen, Caleb Jensen, Leslie Duncan, Feng-Chong Kong, Zoya B. Kurago, Chloe Shay, Yong Teng   +8 more
doaj   +1 more source

Never Smoker OSCC Patient data.

, 2015
Never Smoker OSCC Patient data.
Joel L. Schwartz (823542), Antonia Kolokythas (823540), Yalu Zhou (823541), Guy R. Adami (823543)   +3 more
core   +1 more source