Results 51 to 60 of about 33,871 (216)

TLR4 Expression in Ex-Lichenoid Lesions—Oral Squamous Cell Carcinomas and Its Surrounding Epithelium: The Role of Tumor Inflammatory Microenvironment

open access: yesBiomolecules, 2022
Toll-like receptors (TLRs) regulate innate and adaptive immune responses. Moreover, TLRs can induce a pro-survival and pro-proliferation response in tumor cells.
Fernanda Visioli   +18 more
doaj   +1 more source

Expression profiles of LPCAT1 in OSCC-derived cell lines and OSCC samples.

open access: yes, 2015
(A) Quantification of LPCAT1 mRNA levels in OSCC-derived cell lines by qRT-PCR analysis. To determine the mRNA expression status of LPCAT1, we performed qRT-PCR analysis using 9 OSCC-derived cell lines (HSC-2, HSC-3, HSC-4, Sa3, SAS, Ca9–22, KOSC2, HO-1 ...
Hidetaka Yokoe (710306)   +10 more
core   +1 more source

Analysis of Notch1 and Notch3 Signaling Pathway Components in Benign Prostatic Hyperplasia and Prostate Cancer Patients

open access: yesJournal of Clinical Laboratory Analysis, EarlyView.
This study evaluates the association between Notch1 and Notch3 genetic variations and serum protein levels in patients with benign prostatic hyperplasia and prostate cancer. While genetic variations showed no significant link to disease risk, serum protein levels were significantly lower in prostate cancer and metastatic groups compared to healthy ...
Emine Yagci   +4 more
wiley   +1 more source

Effects of OSCC cell-derived exosomes on proliferation, migration, and invasion of OSCC cells.

open access: yes, 2016
OSCC cell lines were incubated in the presence or absence of exosomes (12.5, 25, and 50 μg) for 24 (A), 10 (B), or 18 h (C). The viable (A), migrating (B), and invading (C) cell numbers were then determined by using the MTT, wound healing, and invasion ...
Eri Sasabe (2157916)   +2 more
core   +1 more source

Triptolide Suppresses Tongue Squamous Cell Carcinoma Progression via PI3K–AKT Pathway Inhibition: An Integrative Network Pharmacology and Experimental Validation Study

open access: yesThe Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Tongue squamous cell carcinoma, the most aggressive subtype of oral squamous cell carcinoma, which is associated with high mortality, frequent recurrence, and early lymph‐node metastasis. Triptolide, a bioactive diterpenoid from Tripterygium wilfordii, exhibits broad anticancer activity.
Shan‐Shan Wang   +3 more
wiley   +1 more source

Bilateral Ophthalmoplegia After Neoadjuvant Pembrolizumab for Oral Cavity Squamous Cell Carcinoma

open access: yesThe Laryngoscope, EarlyView.
The role of immune checkpoint inhibition (ICI) therapy in the treatment of head and neck squamous cell carcinoma (HNSCC) is expanding with increased utilization of neoadjuvant and adjuvant pembrolizumab in the setting of locally advanced disease. This report describes the presentation and management of the first known case of pembrolizumab‐induced ...
Leonard E. Estephan   +3 more
wiley   +1 more source

Data‐Independent Acquisition Mass Spectrometry in Tumor Classification and Cancer Biomarker Research

open access: yesMass Spectrometry Reviews, EarlyView.
Abstract Cancer treatment is far from optimal also because current classification systems do not reflect the complex molecular status of the tumor and its phenotype in sufficient detail. To construct molecular tumor classifiers, omics tools provide complex molecular data reflecting many aspects from genotype to phenotype.
Jan Simonik   +3 more
wiley   +1 more source

Association of hBD-1 expression with prognosis of OSCC.

open access: yes, 2014
A) Examples of negative, weak and strong staining of hBD-1 protein in tissue core from the tissue microarray. The lower panels displayed a magnified vision of the area in the corresponding black box.
Xinhua Liang (540809)   +16 more
core   +1 more source

Mass Spectrometry Insights Into Post‐Translational Modifications in Extracellular Vesicles

open access: yesMass Spectrometry Reviews, EarlyView.
ABSTRACT Extracellular vesicles (EVs) are membrane‐enclosed structures secreted by virtually all living cells, serving as essential mediators of intercellular communication in both physiological and pathological processes. There is growing interest in their potential applications as biomarkers, therapeutic targets, and drug delivery systems, which ...
Dávid Virág   +5 more
wiley   +1 more source

Anti-PD-1 Therapy is Beneficial for the Survival of Patients with Oral Squamous Cell Carcinoma

open access: yesCancer Management and Research, 2022
Liang Feng,1 Ke Yin,2 Suxin Zhang,3 Zhong Chen,3 Yang Bao,3 Tianke Li3 1Department of Stomatology, Baoding First Central Hospital, Baoding, Hebei, People’s Republic of China; 2Department of Stomatology, Xingtai People’s Hospital, Xingtai, Hebei, People’s
Feng L   +5 more
doaj  

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