Results 61 to 70 of about 33,871 (216)

Margin Status and Local Recurrence in Early‐Stage Oral‐Cavity Squamous Cell Carcinoma: Analysis of Reresection Outcomes

open access: yesOtolaryngology–Head and Neck Surgery, EarlyView.
Abstract Objective To assess the impact of surgical margin status and re‐resection on local recurrence (LR) in early‐stage oral cavity squamous cell carcinoma (OCSCC). Study Design Retrospective analysis of 352 patients with cT1‐2N0 OCSCC. Setting Tertiary care center from 2005 to 2024.
Hannah J. Brown   +5 more
wiley   +1 more source

Impact on patients with oral squamous cell carcinoma in different anatomical subsites: a single-center study in Taiwan

open access: yesScientific Reports, 2021
The incidence of oral cavity squamous cell carcinoma (OSCC) is particularly high in South Asia. According to the National Comprehensive Cancer Network, OSCC can arise in several subsites.
Nan-Chin Lin   +3 more
doaj   +1 more source

Effects of heparin on OSCC cell-derived exosome-induced proliferation, migration, and invasion of OSCC cells.

open access: yes, 2016
OSCC cell lines were treated with 10 μg/mL heparin only once at the beginning of the experiment (single administration group) or every 4 h (multiple administration group) in the presence or absence of 50 μg exosomes for 16 h (A), 24 h (B), 10 h (C), or ...
Eri Sasabe (2157916)   +2 more
core   +1 more source

Safety and Efficacy of the Versius Surgical System in Transoral Robotic Surgery: A Prospective Study

open access: yesOtolaryngology–Head and Neck Surgery, EarlyView.
Abstract Objective To evaluate the safety and feasibility of the Versius surgical robotic system for transoral robotic surgery in benign and malignant head and neck indications. Study Design Open‐label, prospective, single‐arm, phase II clinical trial. Setting Liverpool Head and Neck Centre, United Kingdom. Methods Between December 2023 and March 2025,
Jason C. Fleming   +11 more
wiley   +1 more source

Effects of macrophages in OSCC progression

open access: yes
Macrophages are crucial immune cells within the tumor microenvironment (TME), involved in regulating tumor proliferation, invasion, metastasis, ECM remodeling, angiogenesis, and immunosuppression. Although more and more experimental evidence and clinical
Bo Li, Chunling Dong, Xiaodan Dong
core   +1 more source

MDSCs in OSCC tissues were associated with the poor prognosis of OSCC patients.

open access: yes, 2020
A. Immunohistochemical staining was use to examine the infiltration of CD33+ MDSCs. The data showed that the infiltration of CD33+ cells in OSCC tissues was significant higher than in premalignant lesion. Representative figures were shown. B. The overall
Sha-sha Wang (3713548)   +11 more
core   +1 more source

TP53 mutations orchestrate partial EMT states in oral squamous cell carcinoma: spatially resolved and in vitro preliminary insights into tumour plasticity

open access: yesThe Journal of Pathology, EarlyView.
Abstract TP53 is the most frequently mutated gene in oral squamous cell carcinoma (OSCC); however, its role in promoting epithelial–mesenchymal transition (EMT) and tumour progression remains unclear, particularly within the context of intra‐tumour heterogeneity.
Rana Alaaeldin Ibrahim   +9 more
wiley   +1 more source

Oral Cancer

open access: yes
Oral cancer contributes to approximately 3–10% of all cancer mortality worldwide, and its incidence is continuously increasing due to environmental conditions and harmful modern lifestyles.

core   +1 more source

Tumor-associated MDSCs promoted VM of OSCC cells.

open access: yes, 2020
A. Tube-like structure formation on Matrigel in Cal-27 and SCC-25 cells. OSCC cells co-cultured with OSCC derived MDSCs showed a stronger ability of VM formation compared with the control and cells co-cultured with health MDSCs. B.
Sha-sha Wang (3713548)   +11 more
core   +1 more source

Biomarkers Predictive of Immunotherapy Efficacy in Head and Neck Squamous Cell Carcinoma: Current Insights and Future Perspectives

open access: yesWorld Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT With the approval of immunotherapies by regulatory bodies, head and neck squamous cell carcinoma (HNSCC) treatment has been revolutionized, and anti‐programmed cell death‐1 (anti‐PD‐1) agents are now the standard for platinum‐resistant recurrent/metastatic HNSCC.
Xiao‐Tong Yan   +2 more
wiley   +1 more source

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