Results 81 to 90 of about 33,871 (216)

Targeting CKIP‐1 for Disease Therapy: Cellular Functions, Molecular Networks, and Clinical Potential

Cell Proliferation, EarlyView.
CKIP‐1, as a scaffold protein with special structural domains, treats related diseases through multiple emerging targeted technologies.
Xin Huang, Shijie Lv, Lejia Li, Jirong Xie, Zhengguo Cao   +4 more
wiley   +1 more source

Oct4 downregulation abrogate the cancer stemness in OSCC-CSCs.

, 2014
(A) Representative images of tumor sphere formation ability of control-GFP or Oct4-overexpressing OSCCs. (B) Single cell suspensions of OSCC-CSCs were transduced with sh-Luc or sh-Oct4 lentivirus for 3 days.
Lo-Lin Tsai (514932), Chuan-Hang Yu (514239), Cheng-Chia Yu (194788), Shiuan-Shinn Lee (432592), Yu-Chao Chang (278573), Fang-Wei Hu (514933)   +5 more
core   +1 more source

Transmembrane MUC1 assists oral microbial colonization in oral mucosa of potentially malignant disorders and oral squamous carcinoma

European Journal of Oral Sciences, EarlyView.
Abstract Transmembrane mucin 1 (tMUC1) provides oral mucosal barrier against pathogens. The invasion of oncopathogenic microbes can promote cancerous proliferation of cells via inflammatory responses, abnormal cellular signaling, angiogenesis, anti‐adhesion, and tumorigenesis.
Lauriina Soiniemi, Matias Kanniainen, Saga Ramsay, Arja Kullaa, Bina Kashyap   +4 more
wiley   +1 more source

Assessment of Expression of Mast Cells Density in Oral Premalignant and Malignant Lesions by Histochemical Analysis

Journal of Pharmacy and Bioallied Sciences
Aim: Assessment of mast cells density expression in oral premalignant and malignant lesions by histochemical analysis. Materials and Methods: The study used a total of 120 tissue blocks that were formalin-fixed and paraffin-embedded.
Mohammed Abidullah, Bushra Anjum, Shaikh Mohammed Imran Saudagar, Swathi Jahagirdar, Peddisetty Govind Raj Pankaj Mallik, Mediconda Shivaratna   +5 more
doaj   +1 more source

CircGDI2 Regulates the Proliferation, Migration, Invasion and Apoptosis of OSCC via miR-454-3p/FOXF2 Axis

Cancer Management and Research, 2021
Dan Shi,1 Huiyun Li,2 Junge Zhang,3 Yadong Li1 1Department of Oral Medicine Centre, Henan Provincial People’s Hospital, Zhengzhou, Henan, People’s Republic of China; 2Department of Anesthesiology, Henan Provincial People’s Hospital ...
Shi D, Li H, Zhang J, Li Y
doaj  

Abstract 2724: Brush biopsy miRNA based OSCC detection and diagnosis

, 2017
RNA based diagnosis and prognosis of squamous cell carcinoma has been slow to come to the clinic. Improvements in RNA measurement, statistical evaluation, and sample preservation still have not made these methods accurate enough to allow truly ...
Guy R. Adami, Yalu Zhou, Jessica L. Tang, Antonia Kolokythas, Joel Epstein, Gina D. Jefferson, Joel L. Schwartz, Michael Markiewicz   +7 more
core   +1 more source

AI‐based segmentation of occult cervical lymph node metastases: potential reduction of cytokeratin staining

Histopathology, EarlyView.
Deep learning enables accurate detection of occult cervical lymph node metastases on routine H&E sections, showing strong concordance with cytokeratin staining and potential to reduce reliance on immunohistochemistry. Background Detection of occult cervical lymph node metastases is critical for accurate staging and treatment planning in oral cavity ...
Gil Akrish, Elad Yoshai, Sharon Akrish, Natan T. Shaked   +3 more
wiley   +1 more source

Clinicopathological characteristics of the OSCC patients.

, 2014
Clinicopathological characteristics of the OSCC patients.
Stefanie Mikolajczak (668105), Matthias Kreppel (668103), Jens Peter Klussmann (379678), Simon F. Preuss (526813), Inga M. C. Seuthe (668101), Moritz F. Meyer (668100), Uta Drebber (379676), Marcus O. Klein (668104), Oliver Siefer (668102), Christian U. Huebbers (526816)   +9 more
core   +1 more source

Micronucleus Frequency Test in Epithelial Cells Desquamated From the Oral Mucosa of Patients With Fanconi Anemia

Journal of Oral Pathology &Medicine, EarlyView.
ABSTRACT Background Fanconi anemia (FA) is a rare genetic disorder predisposing patients to oral squamous cell carcinoma (OSCC). Hematopoietic stem cell transplantation (HSCT) corrects bone marrow failure but may increase the risk of malignancies. Exfoliative cytology and the micronucleus (MN) test provide noninvasive assessment of genomic instability.
Bárbara Soldatelli Ballardin, Pâmela Olivia de Moura, Pedro Leonardo Czmola de Lima, Juliana Lucena Schussel, Cassius Carvalho Torres‐Pereira   +4 more
wiley   +1 more source

Efficacy of Integrating Immunotherapy with Surgical Resection in Oral Squamous Cell Carcinoma: A Clinical Study

Journal of Pharmacy and Bioallied Sciences
Purpose: This research evaluates the efficacy of integrating immunotherapy with surgical resection in the treatment of “oral squamous cell carcinoma (OSCC).” By analyzing clinical outcomes, we aim to provide evidence for a combined therapeutic approach ...
Kala Bagavathy, Angshuman Saha, Maryada Sravani, Manrit Milina, Anish Nelson, Lavanya Haridas Pasalkar, B. S. Dayanithi   +6 more
doaj   +1 more source