Results 231 to 240 of about 1,311,722 (333)

Tunable Enhancement of T Cell Expansion Through Modulation of Stiffness and Adhesion Receptor Engagement in an Engineered Hydrogel Platform

Advanced Materials, EarlyView.
We develop a hydrogel scaffold with controlled substrate stiffness and ligand functionalization for cell culture. Stiff substrates presenting CD3/CD28/CD2 ligands induce 2000‐fold expansion of T cells; this is 68% greater than the clinical standard (Dynabeads) and the first hydrogel capable of large‐scale expansion. Although expanding at a lower yield,
Niroshan Anandasivam, Rabia Ali, Lordean Gustinvil, Matthew J. Rosenwasser, Iain E. Dunlop, Derfogail Delcassian   +5 more
wiley   +1 more source

Inhibition of inositol 1,4,5-trisphosphate-induced Ca2+ release by cAMP-dependent protein kinase in a living cell.

Proceedings of the National Academy of Sciences of the United States of America, 1998
Svetlana Tertyshnikova, Alan Fein
semanticscholar   +1 more source

Rapid Fabrication of Self‐Propelled and Steerable Magnetic Microcatheters for Precision Medicine

Advanced Materials, EarlyView.
A rapid Joule heating fabrication method for the production of self‐propelling, adaptive microcatheters, with tunable stiffness and integrated microfluidic channels is presented. Demonstrated through three microrobotic designs, including a steerable guiding catheter, an untethered wave‐crawling TubeBot, and a distal‐end propelled microcatheter, it was ...
Zhi Chen, Boris Rivkin, David Castellanos‐Robles, Ivan Soldatov, Lukas Beyer, Mariana Medina‐Sánchez   +5 more
wiley   +1 more source

Calcium signaling is required for anterior patterning in the mouse embryo. [PDF]

PLoS Biol
Stower MJ, Tyser RCV, Thowfeequ S, Zhou F, Portela M, Miti K, Sugnaseelan J, Lu X, Srinivas S.   +8 more
europepmc   +1 more source

Remorphable Architectures: Reprogramming Global Bistability through Locally Bistable Metamaterials

Advanced Materials, EarlyView.
Local bistable reconfiguration in mechanical metamaterials is leveraged in globally bistable architectures to enable in situ reprogrammable transition pathways through state flip of individual building blocks. The local‐to‐global correspondence of instabilities empowers soft robotic systems with on‐demand morphing traits, as well as aerospace ...
Lei Wu, Shujia Chen, Ali Elias Acha, Damiano Pasini   +3 more
wiley   +1 more source

The redox rhythm gates immune-induced cell death distinctly from the genetic clock. [PDF]

Proc Natl Acad Sci U S A
Karapetyan S, Mwimba M, Chen T, Yao Z, Dong X.   +4 more
europepmc   +1 more source

Multifunctional Fluidic Units for Emergent, Responsive Robotic Behaviors

Advanced Materials, EarlyView.
A multifunctional reconfigurable fluidic unit can be used as sensor, valve and actuator is presented. A unique configuration combines the features of the three components as a Responsive self‐oscillating actuator. The remarkable versatility of the fluidic unit is demonstrated by building different robots with the same fluidic units only by varying ...
Mostafa Mousa, Alberto Comoretto, Johannes T.B. Overvelde, Antonio E. Forte   +3 more
wiley   +1 more source

Physical Intelligence in Small‐Scale Robots and Machines

Advanced Materials, EarlyView.
“Physical intelligence” (PI) empowers biological organisms and artificial machines, especially at the small scales, to perceive, adapt, and even reshape their complex, dynamic, and unstructured operation environments. This review summarizes recent milestones and future directions of PI in small‐scale robots and machines.
Huyue Chen, Metin Sitti
wiley   +1 more source

Spatially bound functional heterogeneity drives modular organization in β-cell networks. [PDF]

Biophys J
Duh M, Šterk M, Križančić Bombek L, MacDonald PE, Stožer A, Gosak M.   +5 more
europepmc   +1 more source

Kelvin Probe Force Microscopy in Bionanotechnology: Current Advances and Future Perspectives

Advanced Materials, EarlyView.
Kelvin probe force microscopy (KPFM) enables the nanoscale mapping of electrostatic surface potentials. While widely applied in materials science, its use in biological systems remains emerging. This review presents recent advances in KPFM applied to biological samples and provides a critical perspective on current limitations and future directions for
Ehsan Rahimi, Mario Palacios‐Corella, Arjan Mol, Salvador Pané, Josep Puigmartí‐Luis   +4 more
wiley   +1 more source