Results 71 to 80 of about 5,512,868 (262)

ROS mediates interferon gamma induced phosphorylation of Src, through the Raf/ERK pathway, in MCF-7 human breast cancer cell line [PDF]

, 2017
Interferon gamma (IFN-ɣ) is a pleiotropic cytokine which plays dual contrasting roles in cancer. Although IFN-ɣ has been clinically used to treat various malignancies, it was recently shown to have protumorigenic activities. Reactive oxygen species (ROS)
Asad Zeidan, Nabil El-Zein, Badran, Bassam M., Bassam Badran, Kazem Zibara, Nouhad Kassem, El-Zein, Nabil, Kassem, Nouhad A., Zeidan, Asad, Hassan Bjeije, Bjeije, Hassan, Zibara, Kazem   +11 more
core   +1 more source

Xmrks the Spot: Fish Models for Investigating Epidermal Growth Factor Receptor Signaling in Cancer Research

, 2021
Studies conducted in several fish species, e.g., Xiphophorus hellerii (green swordtail) and Xiphophorus maculatus (southern platyfish) crosses, Oryzias latipes (medaka), and Danio rerio (zebrafish), have identified an oncogenic role for the receptor ...
Jerry D. Monroe, Faiza Basheer, Yann Gibert   +2 more
core   +1 more source

FastNano Liquid: An Automated Platform for Small‐Angle X‐ray Scattering‐Based Materials Discovery

Advanced Engineering Materials, EarlyView.
We present FastNano Liquid, an automated small‐ and wide‐angle X‐ray scattering platform for the combined synthesis and characterization of (nano)materials. The platform is coupled to varied reactor workflows for both in situ studies of reaction kinetics and ex situ screening of synthesis conditions to support machine learning‐guided exploration ...
Pierre‐Baptiste Flandrin, Émeline Cournède, Jens Krarup, Michael Lesa, Foyzul Hasan, Amandine Séné, Arnaud Lahouati, David Benhaiem, Jérémie‐Luc Sanchez, Simon Delacroix, Thierry Gacoin, Fabienne Testard, Damien Faivre, David Carriere, Corinne Chevallard, Olivier Taché, Mark A. Levenstein   +16 more
wiley   +1 more source

Hedgehog Signaling and Truncated GLI1 in Cancer

, 2020
The hedgehog (HH) signaling pathway regulates normal cell growth and differentiation. As a consequence of improper control, aberrant HH signaling results in tumorigenesis and supports aggressive phenotypes of human cancers, such as neoplastic ...
Sara G. Manore, Daniel Doheny, Grace L. Wong, Hui-Wen Lo   +3 more
core   +1 more source

p38γ MAPK Inflammatory and Metabolic Signaling in Physiology and Disease

, 2023
p38γ MAPK (also called ERK6 or SAPK3) is a family member of stress-activated MAPKs and has common and specific roles as compared to other p38 proteins in signal transduction.
Guan Chen, Xiao-Mei Qi
core   +1 more source

Printed Integrated Logic Circuits Based on Chitosan‐Gated Organic Transistors for Future Edible Systems

Advanced Functional Materials, EarlyView.
Edible electronics needs integrated logic circuits for computation and control. This work presents a potentially edible printed chitosan‐gated transistor with a design optimized for integration in circuits. Its implementation in integrated logic gates and circuits operating at low voltage (0.7 V) is demonstrated, as well as the compatibility with an ...
Giulia Coco, Valerio Francesco Annese, Valerio Galli, Ilaria Penna, Debora Russo, Marina Veronesi, Rita Scarpelli, Stefania Sabella, Mario Caironi   +8 more
wiley   +1 more source

Remodeling of calcium signaling and store operated calcium entry as a consequence of human neural progenitor cell differentiation

Scientific Reports
The differentiation of neural progenitor cells into glial and neuronal lineages is a fundamental process in neurodevelopment. This complex process is tightly regulated by several signaling pathways, including calcium signaling. Calcium signaling not only
Silke B. Chalmers, Mélanie Robitaille, Francisco Sadras, Sarah J. Roberts-Thomson, Gregory R. Monteith   +4 more
doaj   +1 more source

Store Operated Calcium Entry in Cell Migration and Cancer Metastasis

, 2021
Ca2+ signaling is ubiquitous in eukaryotic cells and modulates many cellular events including cell migration. Directional cell migration requires the polarization of both signaling and structural elements.
Khaled Machaca, Ayat S. Hammad
core   +1 more source

Counterion Dependent Side‐Chain Relaxation Stiffens a Chemically Doped Thienothiophene Copolymer

Advanced Functional Materials, EarlyView.
Oxidation of a thienothiophene copolymer, p(g3TT‐T2), via different doping strategies and dopant molecules resulted in materials with similar oxidation levels and a high electrical conductivity of ≈100 S cm−1. However, mechanical properties varied significantly, with sub‐glass transition temperatures and elastic moduli spanning from –44°C to –3°C and ...
Mariavittoria Craighero, Meghna Jha, Elsa Veronica Flores‐Vela, Joost Kimpel, Andreas Schaefer, Jiali Guo, Jesika Asatryan, Alberto Peinador Veiga, Shuichi Haraguchi, Per‐Anders Carlsson, Jaime Martín, Mariano Campoy‐Quiles, Christian Müller   +12 more
wiley   +1 more source

Cross-talk between signaling pathways can generate robust oscillations in calcium and cAMP. [PDF]

PLoS ONE, 2009
BACKGROUND:To control and manipulate cellular signaling, we need to understand cellular strategies for information transfer, integration, and decision-making.
Fernando Siso-Nadal, Jeffrey J Fox, Stéphane A Laporte, Terence E Hébert, Peter S Swain   +4 more
doaj   +1 more source