Results 71 to 80 of about 23,536 (303)

Role of Regulator of G Protein Signaling 2 (RGS2) in Ca2+ Oscillations and Adaptation of Ca2+ Signaling to Reduce Excitability of RGS2–/– Cells [PDF]

Journal of Biological Chemistry, 2004
Regulators of G protein signaling (RGS) proteins accelerate the GTPase activity of Galpha subunits to determine the duration of the stimulated state and control G protein-coupled receptor-mediated cell signaling. RGS2 is an RGS protein that shows preference toward Galpha(q).
Xinhua, Wang, Guojin, Huang, Xiang, Luo, Josef M, Penninger, Shmuel, Muallem   +4 more
openaire   +2 more sources

A FMRFamide-like neuropeptide FLP-12 signaling regulates head locomotive behaviors in Caenorhabditis elegans [PDF]

Neuropeptides play a critical role in regulating behaviors across organisms, but the precise mechanisms by which neuropeptides orchestrate complex behavioral programs are not fully understood.
Park, Cheon-Gyu, Heo, Woojung, Suh, Byung-Chang, Kang, KyeongJin, Moon, Kyeong Min, Du, Eun Jo, Kim, Kyuhyung, Kim, Do-Young, Cho, Jihye, Hahm, Jeong-Hoon   +9 more
core   +1 more source

Counterion Dependent Side‐Chain Relaxation Stiffens a Chemically Doped Thienothiophene Copolymer

Advanced Functional Materials, EarlyView.
Oxidation of a thienothiophene copolymer, p(g3TT‐T2), via different doping strategies and dopant molecules resulted in materials with similar oxidation levels and a high electrical conductivity of ≈100 S cm−1. However, mechanical properties varied significantly, with sub‐glass transition temperatures and elastic moduli spanning from –44°C to –3°C and ...
Mariavittoria Craighero, Meghna Jha, Elsa Veronica Flores‐Vela, Joost Kimpel, Andreas Schaefer, Jiali Guo, Jesika Asatryan, Alberto Peinador Veiga, Shuichi Haraguchi, Per‐Anders Carlsson, Jaime Martín, Mariano Campoy‐Quiles, Christian Müller   +12 more
wiley   +1 more source

Distinct anti-dyskinetic effects of amantadine and group II metabotropic glutamate receptor agonist LY354740 in a rodent model: An electrophysiological perspective

Neurobiology of Disease, 2020
L-DOPA-induced dyskinesia (LID) is a major complication of long-term dopamine replacement therapy in Parkinson's disease. Characteristic neural oscillation and abnormal activity of striatal projection neurons (SPNs) are typical pathological events of LID,
Cong Zheng, Yan Xu, Guiqin Chen, Yang Tan, Weiqi Zeng, Ji Wang, Chi Cheng, Xiaoman Yang, Shuke Nie, Zhentao Zhang, Xuebing Cao   +10 more
doaj   +1 more source

Circadian regulation of dentate gyrus excitability mediated by G-protein signaling

Cell Reports, 2023
Summary: The central circadian regulator within the suprachiasmatic nucleus transmits time of day information by a diurnal spiking rhythm driven by molecular clock genes controlling membrane excitability.
Jose Carlos Gonzalez, Haeun Lee, Angela M. Vincent, Angela L. Hill, Lacy K. Goode, Gwendalyn D. King, Karen L. Gamble, Jacques I. Wadiche, Linda Overstreet-Wadiche   +8 more
doaj   +1 more source

Strain‐Programmable Luminescent Adhesive Patch With Tartrazine‐Mediated Optical Skin Clearing for Photochemical Tissue Bonding

Advanced Functional Materials, EarlyView.
We propose a suture‐complementary approach that integrates optical skin clearing with a strain‐programmable luminescent adhesive patch. Hyaluronic acid promotes transdermal delivery of tartrazine to improve optical clearing and stabilizes its interaction with a photosensitizer. Optical clearing increases the penetration depth of visible light into skin,
Seong‐Jong Kim, Kyungjoo Jo, Kwanghyeon Park, Jun Hee Kim, Jong Hyeong Cho, Inhoo Choi, Sei Kwang Hahn   +6 more
wiley   +1 more source

Study of the Synchronization and Transmission of Intracellular Signaling Oscillations in Cells Using Bispectral Analysis

Biology
The oscillation synchronization analysis in biological systems will expand our knowledge about the response of living systems to changes in environmental conditions. This knowledge can be used in medicine (diagnosis, therapy, monitoring) and agriculture (increasing productivity, resistance to adverse effects).
Maxim E. Astashev, Dmitriy A. Serov, Arina V. Tankanag, Inna V. Knyazeva, Artem A. Dorokhov, Alexander V. Simakin, Sergey V. Gudkov   +6 more
openaire   +3 more sources

Omnipolar Magnetic Field Detection by Superlattice‐Based Hall Sensor

Advanced Functional Materials, EarlyView.
Magnetic‐field‐induced electronic switching is demonstrated in unit‐cell‐engineered La0.7Sr0.3MnO3–BiFeO3 superlattices. Distinct substrate terminations modify magnetic and transport properties. Hall resistance measurements show omnipolar, hysteretic anomalous Hall switching above the Curie temperature, arising from Fe─Mn interfacial exchange, enabling
Mark Huijben, Nicolas Gauquelin, Arno Annys, Zhaoliang Liao, Jo Verbeeck, Guus Rijnders, Gertjan Koster   +6 more
wiley   +1 more source

Achieving High ON State Current through Ferroelectric Polarization‐Dependent Interfacial Resistance Switching in Undoped Orthorhombic HfO2 Films

Advanced Functional Materials, EarlyView.
Ferroelectric tunnel junction devices based on epitaxial undoped ferroelectric HfO2 films demonstrate stable switching endurance of over 106 switching cycles, low write voltages of ±3 V, 16 measured resistance states, and neuromorphic capability.
Markus Hellenbrand, Nuno Estrócio, Ji S. Kim, Babak Bakhit, Marian C. Istrate, Corneliu Ghica, Tiago Rebelo, Nives Strkalj, Abin Varghese, Bernardo Almeida, Luís S. Marques, Bipin Rajendran, Judith L. MacManus‐Driscoll, José P. B. Silva   +13 more
wiley   +1 more source

Repetitive mitochondrial Ca 2+ signals synchronize with cytosolic Ca 2+ oscillations in the pancreatic beta-cell line, MIN6 [PDF]

Diabetologia, 1998
We examined the relationship between cytosolic Ca2+ concentration ([Ca2+]c) and mitochondrial matrix Ca2+ concentration ([Ca2+]m) in the pancreatic beta-cell line, MIN6. [Ca2+]c was monitored in a single or a group (30 cells) of fura-2-loaded MIN6 cells, and [Ca2+]m was measured in a group (1 x 10[6] cells) of MIN6 cells stably transfected with ...
M, Nakazaki, H, Ishihara, M, Kakei, K, Inukai, T, Asano, J I, Miyazaki, H, Tanaka, M, Kikuchi, T, Yada, Y, Oka   +9 more
openaire   +2 more sources