Results 41 to 50 of about 25,792 (254)

Oncostatin M Maintains Naïve Pluripotency of mESCs by Tetraploid Embryo Complementation (TEC) Assay

Frontiers in Cell and Developmental Biology, 2021
It has been well established that leukemia inhibitory factor (LIF) is essential for maintaining naïve pluripotency of embryonic stem cells (ESCs). Oncostatin M (OSM) is a member of the IL-6 family of cytokines which share gp130 as a receptor subunit, and
Xiaoying Ye, Xiaoying Ye, Chenglei Tian, Chenglei Tian, Chenglei Tian, Linlin Liu, Linlin Liu, Guofeng Feng, Guofeng Feng, Kairang Jin, Kairang Jin, Haiying Wang, Haiying Wang, Jiyu Chen, Jiyu Chen, Lin Liu, Lin Liu   +16 more
doaj   +1 more source

Exploring Data Model Relations in OpenStreetMap

Future Internet, 2017
The OpenStreetMap (OSM) geographic data model has three principal object types: nodes (points), ways (polygons and polylines), and relations (logical grouping of all three object types to express real-world geographical relationships).
Hippolyte Pruvost, Peter Mooney
doaj   +1 more source

Diabetes-Associated Myelopoiesis Drives Stem Cell Mobilopathy Through an OSM-p66Shc Signaling Pathway

Diabetes, 2019
Diabetes impairs the mobilization of hematopoietic stem/progenitor cells (HSPCs) from the bone marrow (BM), which can worsen the outcomes of HSPC transplantation and of diabetic complications.
M. Albiero, Stefano Ciciliot, S. Tedesco, L. Menegazzo, Marianna D’Anna, Valentina Scattolini, R. Cappellari, G. Zuccolotto, A. Rosato, A. Cignarella, M. Giorgio, A. Avogaro, G. Fadini   +12 more
semanticscholar   +1 more source

Model application for rapid detection of the exact location when calling an ambulance using OGC Open GeoSMS Standards

Open Geosciences, 2016
The web has penetrated just about every sphere of human interest and using information from the web has become ubiquitous among different categories of users.
Sukic Enes, Stoimenov Leonid
doaj   +1 more source

Volunteered and crowdsourced geographic information: the OpenStreetMap project

Journal of Spatial Information Science, 2020
Advancements in technology over the last two decades have changed how spatial data are created and used. In particular, in the last decade, volunteered geographic information (VGI), i.e., the crowdsourcing of geographic information, has revolutionized ...
Michela Bertolotto, Gavin McArdle, Bianca Schoen-Phelan   +2 more
doaj   +1 more source

HIGH expression of OSM and IL-6 are associated with decreased breast cancer survival: synergistic induction of IL-6 secretion by OSM and IL-1β

OncoTarget, 2019
Chronic inflammation has been recognized as a risk factor for the development and maintenance of malignant disease. Cytokines such as interleukin-6 (IL-6), oncostatin M (OSM), and interleukin-1 beta (IL-1β) promote the development of both acute and ...
Ken Tawara, Hannah Scott, Jacqueline M. Emathinger, Cody L Wolf, Dollie LaJoie, Danielle S. Hedeen, L. Bond, Paul G. Montgomery, C. Jorcyk   +8 more
semanticscholar   +1 more source

Microglial dynamics and ferroptosis induction in human iPSC‐derived neuron–astrocyte–microglia tri‐cultures

FEBS Open Bio, EarlyView.
A tri‐culture of iPSC‐derived neurons, astrocytes, and microglia treated with ferroptosis inducers as an Induced ferroptosis model was characterized by scRNA‐seq, cell survival, and cytokine release assays. This analysis revealed diverse microglial transcriptomic changes, indicating that the system captures key aspects of the complex cellular ...
Hongmei Lisa Li, Hiroko Ohmiya, Sou Sakamoto, Masato Yugami, Akiko Oki, Makoto Furusawa, Yan Ling   +6 more
wiley   +1 more source

Alcohol‐induced altered glycans in human tracheal epithelial cells promote bacterial adhesion

FEBS Open Bio, EarlyView.
Alcohol induces altered glycans to promote bacteria adhesion. Heavy alcohol drinking is known to increase the risk of bacterial pneumonia. However, the link between alcohol levels and risk of infection remains underexplored. Recently, we found that alcohol induced α2‐6sialo mucin O‐glycans in human tracheobronchial epithelial cells, which mediated the ...
Pi‐Wan Cheng, Souvik Datta, Derrick R. Samuelson   +2 more
wiley   +1 more source

esy-osmfilter – A Python Library to Efficiently Extract OpenStreetMap Data

Journal of Open Research Software, 2020
OpenStreetMap is the largest freely accessible geographic database of the world. The necessary processing steps to extract information from this database, namely reading, converting and filtering, can be very consuming in terms of computational time and ...
Adam Pluta, Ontje Lünsdorf
doaj   +1 more source

OSM May Serve as a Biomarker of Poor Prognosis in Clear Cell Renal Cell Carcinoma and Promote Tumor Cell Invasion and Migration

International Journal of Genomics, 2023
Background. Currently, the role of oncostatin M (OSM) in clear cell renal cell carcinoma (ccRCC) has not been investigated. This study will explore the impact of OSM on ccRCC expression, prognosis, and cell function. Materials and Methods. In this study,
Shuzhang Wei, Yin Chen, Xiaokai Shi, Li Zuo, Lifeng Zhang   +4 more
doaj   +1 more source