Results 81 to 90 of about 86,111 (239)

Structures of complete extracellular assemblies of type I and type II Oncostatin M receptor complexes

Nature Communications
Oncostatin M (OSM) is a unique Interleukin 6 (IL-6) family cytokine that plays pivotal roles in numerous biological events by signaling via two types of receptor complexes.
Yi Zhou, Panayiotis E. Stevis, Jing Cao, George Ehrlich, Jennifer Jones, Ashique Rafique, Mark W. Sleeman, William C. Olson, Matthew C. Franklin   +8 more
doaj   +1 more source

Integrating Radiomics and Computational Pathology to Predict Early Recurrence of Pancreatic Ductal Adenocarcinoma and Uncover Its Biological Basis in Tumor Microenvironment

Advanced Science, EarlyView.
Accurate prediction of early recurrence in pancreatic ductal adenocarcinoma is vital for optimizing treatment. A novel, integrated radiomics‐pathology machine learning model successfully forecasts recurrence risks by analyzing preoperative CT images and computational pathology.
Sihang Cheng, Fuze Cong, Shenbo Zhang, Rui Lv, Wenjia Zhang, Xinyi Ke, Juncheng Wu, Zhonghe Zhao, Kui Zhao, Di Dong, Ruofan Zhang, Zhengyu Jin, Max Seidensticker, Zhiwei Wang, Huanwen Wu, Xianlin Han, Nan Hong, Huadan Xue   +17 more
wiley   +1 more source

The Clinical Characteristics and Outcomes of Multiple Myeloma Patients With Oligo or Non-Secretory Relapse-A Retrospective Cohort Study. [PDF]

Hematol Oncol
ABSTRACT Oligo‐secretory and non‐secretory MM present a clinical challenge due to the difficulties in initial diagnosis, response to treatment assessment, and relapse detection. They are excluded from most clinical trials, which typically require measurable disease.
Vaxman I, Zamir I, Cohen I, Fridberg G, Shragai T, Trestman S, Baran TZ, Luttwak E, Shmuel R, Melamed N, Levy S, Avivi I, Raanani P, Dispenzieri A, Gertz MA, Cohen YC.   +15 more
europepmc   +2 more sources

Liver Kinase B1 in CD11c+ Cells Inhibits Fibrosis in Chronic Pancreatitis via the Oncostatin M Signaling

Advanced Science, EarlyView.
This study demonstrates significantly reduced Lkb1 expression in CD11c+ cells in chronic pancreatitis (CP) patients and animal models. Lkb1 deletion enhances CD11c+CD206+ macrophage infiltration and reprograms pancreatic stellate cells (PSCs) via OSM signaling.
Wenqing Zhang, Shan Guo, Yu Zhang, He Ren, Ke Lei, Chenyang Zhao, Qian Yu, Hongqing Luo, Yujing Xiao, Xiaoming Feng, Xiaoyu Li   +10 more
wiley   +1 more source

OpenStreetMap e la prima conferenza OSMit

GEOmedia, 2009
OpenStreetMap and the first OSMit conference This month’s article features a brief presentation of the OpenStreetMap project, initiated by a single user in 2004 with the aim of creating a free map of the world, editable following wiki-like rules, and ...
Luca Dellucchi, Niccolò Rigacci, Paolo Cavallini   +2 more
doaj  

Temporal Analysis of Activity Patterns of Editors in Collaborative Mapping Project of OpenStreetMap

, 2013
In the recent years Wikis have become an attractive platform for social studies of the human behaviour. Containing millions records of edits across the globe, collaborative systems such as Wikipedia have allowed researchers to gain a better understanding
Almeida R. B., Golder S. A., Haklay M., Hristova D., Lieberman M. D., Thamm M., Zielstra D.   +6 more
core   +1 more source

Lattice Coherency‐Driven (111)‐Oriented Wide Bandgap Perovskite Films

Advanced Energy Materials, EarlyView.
Methylammonium lead chloride (MAPbCl3)‐derived seed templates regulate wide‐bandgap perovskite crystallization through coupled thermodynamic and kinetic effects. Lattice‐coherent templating lowers the energy cost for (111) epilayer growth, while growth retardation controls crystallization kinetics, ultimately producing highly crystalline face‐up (111 ...
Yu‐Na Lee, Hyo Jung Kim, Ji‐Sang Park, Wolfgang Tress, Yasemin Saygili, Hui‐Seon Kim   +5 more
wiley   +1 more source

UNCERTAINTIES OF COMPLETENESS MEASURES IN OPENSTREETMAP – A CASE STUDY FOR BUILDINGS IN A MEDIUM-SIZED GERMAN CITY [PDF]

ISPRS Annals of the Photogrammetry, Remote Sensing and Spatial Information Sciences, 2015
The completeness of buildings in OpenStreetMap (OSM) is estimated for a medium-sized German city and its surroundings by comparing the OSM data with data from an official building cadastre.
T. Törnros, H. Dorn, S. Hahmann, A. Zipf   +3 more
doaj   +1 more source

Osm století Chilandaru

Lidé města, 1999
Výstava fotografických reprodukcí Mirkovićových kopií ikon ze srbského kláštera Chilandaru byla připravena velvylanectvím Svazové republiky Jugoslávie u příležitosti 800. výročí založení této srbské svatyně na Svaté Hoře v Řecku. Výstavu autorsky připravil autor kopií Chranislav Mirković, výtvarnou podobu jí dal Jan Duspěva.
openaire   +1 more source

Intravenous Lipopolysaccharide Challenge in Healthy Participants Reveals Pharmacodynamic Markers in Blood and Bone Marrow for Early‐Phase Oncology Drug Development

Clinical Pharmacology &Therapeutics, EarlyView.
Demonstrating pharmacological effects in early‐phase oncology clinical trials remains challenging, largely due to the lack of robust pharmacodynamic markers. Lipopolysaccharide (LPS) is used as an immune challenge agent in healthy participants to study drugs for autoimmune conditions.
Igor Radanović, Ingrid Tomljanović, Wieke H. Grievink, Diana R. Pereira, Michelle Osse, Peter van Balen, Maria J. Juachon, Marieke L. de Kam, Lisa Pagan, Manon A.A. Jansen, Matthijs Moerland, Jacobus J. Bosch   +11 more
wiley   +1 more source