Results 171 to 180 of about 60,322 (306)

Osmotic laxatives do not alter dabigatran plasma concentration in healthy volunteers - a randomized, controlled, cross-over trial. [PDF]

Front Pharmacol
Weiss-Tessbach M, Dizdarevic AM, Kupis A, Bischof T, Firbas C, Quehenberger P, Derhaschnig U, Frimmel M, Jilma B, Schoergenhofer C.   +9 more
europepmc   +1 more source

Recent advances in the structure, function and regulation of the volume‐regulated anion channels and their role in immunity

The Journal of Physiology, EarlyView.
Abstract figure legend The volume‐regulated anion channel (VRAC), composed of leucine‐rich repeat‐containing 8 (LRRC8) proteins, serves both canonical and non‐canonical functions in vertebrate cells. The canonical function of this channel relates to its original description, which is homeostatic regulation of cell volume in response to hypotonic ...
Sergei Yanushkevich, Aleksandra Zieminska, Joshua Gonzalez, Francisca Añazco, Richard Song, Alejandra Arias‐Cavieres, Sara T. Granados, Junyi Zou, Yan Rao, Axel R. Concepcion   +9 more
wiley   +1 more source

Genetics of conditional extended mycelial cell viability of Streptomyces minutiscleroticus in deep starvation phase implicates the involvement of (p)ppGpp, clpX, and a histidine kinase sasA. [PDF]

Front Microbiol
Chatupale V, Pohnerkar J.
europepmc   +1 more source

Synaptic communication within the microcircuits of pyramidal neurons and basket cells in the mouse prefrontal cortex

The Journal of Physiology, EarlyView.
Abstract figure legend Basket cells represent critical building blocks of neuronal circuits in cortical regions by providing GABAergic innervation to the perisomatic region of their postsynaptic partners. In the mouse prelimbic cortex, the two basket cell types expressing parvalbumin or cholecystokinin/type I cannabinoid receptor receive unitary ...
Zsuzsanna Fekete, Filippo Weisz, Mária Rita Karlócai, Judit M. Veres, Tibor Andrási, Norbert Hájos   +5 more
wiley   +1 more source

Mastering blood gas interpretation: A practical guide for primary care providers. [PDF]

S Afr Fam Pract (2004)
Habib T, Nair A, Murphy S, Saeed H, Ishaya N.   +4 more
europepmc   +1 more source

Sphingosine‐1‐phosphate activates LRRC8 volume‐regulated anion channels through Gβγ signalling

The Journal of Physiology, EarlyView.
Abstract figure legend Sphingosine‐1‐phosphate (S1P) binds to Gi protein‐coupled receptor S1PR1. Upon S1PR1 activation, Gβγ is released from the Gαi‐Gβγ heterotrimer, allowing it to recruit phospholipase Cβ (PLCβ) to the plasma membrane. PLCβ cleaves phosphatidylinositol‐4,5‐bisphosphate (PIP2) into inositol trisphosphate (IP3) and diacylglycerol (DAG).
Yulia Kostritskaia, Sumaira Pervaiz, Anna Klemmer, Malte Klüssendorf, Tobias Stauber   +4 more
wiley   +1 more source

Appropriate Correction of Hyponatremia in a Patient With Psychogenic Polydipsia: A Case Report. [PDF]

Cureus
Olberding CR, Habib F, Richa P, Narvel R.   +3 more
europepmc   +1 more source

Efficacy and Safety of Iodixanol in Computed Coronary Tomographic Angiography and Cardiac Catheterization. [PDF]

J Cardiovasc Dev Dis, 2023
Budoff MJ, Lee HS, Roy SK, Shekar C.
europepmc   +1 more source

Persistence of quantal synaptic vesicle recycling in virtual absence of dynamins

The Journal of Physiology, EarlyView.
Abstract figure legend Figure depicts the key finding from this study. While loss of all dynamins severely debilitates synaptic vesicle retrieval following repetitive activity, retrieval and recycling of individual synaptic vesicles following spontaneous fusion or sparse stimulation are minimally affected.
Olusoji A. T. Afuwape, Natali L. Chanaday, Merve Kasap, Lisa M. Monteggia, Ege T. Kavalali   +4 more
wiley   +1 more source

Unmeasured Osmoles: The Hidden Solutes Obscuring a Hyponatremia Evaluation. [PDF]

Cureus
Mathias J, Lovekar S, Yap J.
europepmc   +1 more source