Results 231 to 240 of about 38,209 (300)

Magnetic Resonance Imaging Evaluation of Functional Differences Between In Vivo Human Kidneys and Discarded Human Kidneys During Ex Vivo Normothermic Machine Perfusion

Artificial Organs, EarlyView.
Comparative MRI of in vivo kidneys and ex vivo donor kidneys during NMP revealed marked physiological differences and limited correspondence with conventional perfusion or injury metrics. These distinct ex vivo MRI signatures emphasize the need to consider parameters beyond conventional in vivo functional markers when assessing organ viability during ...
Tim L. Hamelink, Chris L. Jaynes, L. Annick van Furth, Johannes Castelein, Nathan Ooms, Veerle A. Lantinga, Baran Ogurlu, Xiaopeng Zhou, Ulrike Dydak, Henri G. D. Leuvenink, Anna Krarup Keller, Ronald J. H. Borra, Cyril Moers   +12 more
wiley   +1 more source

Neurological fallout of hyperglycemia: A case report of a rare presentation of osmotic demyelination syndrome. [PDF]

Qatar Med J
Gupta R, Sachar C, Kaktyan P.
europepmc   +1 more source

Identification of drug repurposing candidates for the treatment of polycystic kidney disease

British Journal of Pharmacology, EarlyView.
Background and Purpose Autosomal dominant polycystic kidney disease (ADPKD) is a leading cause of end‐stage renal disease with limited treatment options. Drug repurposing offers a promising strategy to find effective treatments. Experimental Approach We identified birinapant, bardoxolone methyl and salicylic acid as repurposing candidates for ADPKD and
Alina Meyer, Paraskevi Sotiropoulou, Koussai Bouker, Dennis Svedberg, Rebekkah Hammar, Hester Bange, Per Larsson, André Mateus, Daniel R. Dietrich, Per Artursson   +9 more
wiley   +1 more source

A New Method for Quantitative Evaluation Concentration Polarization Under Different Conditions for the Forward Osmosis Process. [PDF]

Membranes (Basel)
Xiao P, Liu L.
europepmc   +1 more source

Harnessing Metabolic Priming to Engineer Human Nucleus Pulposus Macromass Overcoming Scalability‐Phenotype Tradeoff

Cell Proliferation, EarlyView.
Human platelet lysate acts as a metabolic primer for hNPCs, enhancing fatty acid oxidation to drive proliferation while preserving phenotype. This enables construction of high‐quality, large‐size macromasses without necrotic defects, demonstrating exceptional efficacy in repairing degenerated discs in situ and providing a novel paradigm for ...
Yingbo Wang, Ou Hu, Jian Wu, Sha Huang, Peng Lin, Pulin Yan, Yangyang Li, Huaijian Jin, Yutong Wu, Jun Zhu, Jungang Pu, Bo Hu, Jian He, Yibo Gan, Peng Liu   +14 more
wiley   +1 more source

PLIN5 Protects Against Ang II‐Induced Podocyte Lipotoxicity by Interacting With FKBP8 and Preserving Lipid Droplet–Mitochondria Contact

Cell Proliferation, EarlyView.
PLIN5‐FKBP8 tethers lipid droplets to mitochondria to counteract Ang II‐induced lipotoxicity. ABSTRACT Chronic kidney disease (CKD) remains a major global health challenge. Angiotensin II (Ang II)‐induced lipotoxicity is an important contributor to podocyte injury.
Ping Wang, Wenjie Chen, Jingjing Ke, Hongtu Hu, Zhuan Peng, Yue Qi, Guohua Ding, Jijia Hu   +7 more
wiley   +1 more source

Semi-arid grasses combine contrasting strategies of dehydration tolerance associated with carbohydrate storage and embolism resistance under drought. [PDF]

J Exp Bot
Hidalgo-Galvez MD, Akhoun-Piernicka C, Cardozo GA, Morvan-Bertrand A, Prud'homme MP, Barkaoui K, Volaire F.   +6 more
europepmc   +1 more source

Student Perceptions of Digitally Uplifted Learning Across Cohorts in Two Dental Programs: A Mixed Methods Study

European Journal of Dental Education, EarlyView.
ABSTRACT Introduction This study assessed the efficacy of online and blended education for dental students at the University of Queensland (UQ) by exploring student experiences, perceptions, and satisfaction. Materials and Methods This mixed‐methods study surveyed 304 dental students across all year levels using a Likert scale questionnaire focusing on
Ahmed Abdulmunem, Sana Ibrahim, Emily Lee, Jessica Zachar, Ove A. Peters   +4 more
wiley   +1 more source

A simple and high-throughput single pollen genotyping pipeline to study meiosis in apple (Malus x domestica). [PDF]

Plant Methods
Palmers H, Philips L, De Storme N.
europepmc   +1 more source

Dynamic miRNA-host gene co-expression and functional regulation in response to salinity fluctuations during biological invasions. [PDF]

Mar Life Sci Technol
Yan W, Fu R, Huang X, Shenkar N, Zhan A.
europepmc   +1 more source