Ins and outs of therapy of functional proctogenic constipation in children [PDF]
In recent years, chronic constipation has become one of the key challenges in pediatric gastroenterology. Motility disorders in children are often functional; there are mixed (cologenic and proctogenic) and proctogenic disorders.
M. L. Babayan
doaj +2 more sources
OSMOTIC LAXATIVES IN TREATMENT OF CHRONIC CONSTIPATIONS IN CHILDREN
A comparative trial including 80 patients at the age of 1–16 years old was performed in order to evaluate efficacy and safety of osmotic laxatives polyethylene glycol with molecular mass of 4000 kDa and lactulose (46 children received polyethylene glycol,
E. A. Kornienko +3 more
doaj +2 more sources
Chronic constipation (definition, epidemiology, diagnosis): current drug therapy
The most interest among laxatives used in the treatment of functional constipation is earned by Exportale (lactitol monohydrate) which belongs to osmotic laxatives.
O. N. Minushkin
doaj +2 more sources
Our objective was to evaluate the efficacy of daily enemas for the treatment of overactive bladder (OAB) in children. This study was a prospective, controlled trial of 60 children with nonneurogenic OAB.
Steve J. Hodges MD, Marc Colaco MD
doaj +2 more sources
Questions of medication treatment of constipation of functional origin in children
Constipation of functional origin (CFO) is one of the challenges in contemporary pediatrics. Almost every pediatrician constantly has to address the problem in children of all age groups.
T. V. Gasilina, S. V. Belmer
doaj +2 more sources
Modern principles of constipation treatment
The aim of review. To present up-to-date approach to prescription of laxatives at treatment of constipation.Original positions. The laxatives are agents with the various mode of action.
M. A. Livzan
doaj +1 more source
Systematic review of the effectiveness of laxatives in the elderly.
OBJECTIVES: To determine the effectiveness and cost of laxatives in the prevention and treatment of constipation in the elderly. HOW THE RESEARCH WAS CONDUCTED: Randomised controlled trials (RCTs) of treatment or prevention of constipation were included ...
Petticrew, Watt, Sheldon
doaj +2 more sources
Constipation outcomes in children with and without autism spectrum disorder: Insights from a tertiary motility service. [PDF]
Abstract Objectives Autism spectrum disorder (ASD) is commonly associated with gastrointestinal comorbidities, particularly chronic constipation. Despite high clinical burden and frequent tertiary referrals, comparative data describing clinical characteristics, management and outcomes between children with and without ASD—and across ASD severity levels—
Khalid U +4 more
europepmc +2 more sources
Osmotic and stimulant laxatives for the management of childhood constipation. [PDF]
Gordon M +6 more
europepmc +2 more sources
The "GABAergic Brake" on the Spinal Defecation Reflex: A Proposed Neurobiological Model Explaining Clozapine- and Benzodiazepine-Induced Gastrointestinal Hypomotility and Ogilvie's Syndrome. [PDF]
Synergistic “Double Brake” Model on the Spinal Defecation Center in Clozapine‐Induced Constipation. Real‐world data shows BZDRs increase laxative risk in schizophrenia. Mitigating the central GABAergic brake via sedative optimization and maintaining gut microbiota homeostasis prevents fatal Ogilvie's syndrome.
Nagamine T.
europepmc +2 more sources

