Results 51 to 60 of about 116,921 (275)

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

FEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya, Masatake Osawa, Hidefumi Fukumitsu   +2 more
wiley   +1 more source

High dietary lipid level promotes low salinity adaptation in the marine euryhaline crab (Scylla paramamosain)

Animal Nutrition, 2023
The physiological processes involved in adaptation to osmotic pressure in euryhaline crustaceans are highly energy demanding, but the effects of dietary lipids (fat) on low salinity adaptations have not been well evaluated.
Jiaxiang Luo, Chen Ren, Tingting Zhu, Chen Guo, Shichao Xie, Yingying Zhang, Zheng Yang, Wenli Zhao, Xiangsheng Zhang, Jingjing Lu, Lefei Jiao, Qicun Zhou, Douglas R. Tocher, Min Jin   +13 more
doaj   +1 more source

A Depolarizing Leak in Sodium Bicarbonate Cotransporter NBCe1 Causes Brain Edema

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives SLC4A4 encodes electrogenic sodium bicarbonate cotransporter NBCe1, prominently expressed in kidney and brain. Recessive loss‐of‐function variants in SLC4A4 cause proximal renal tubular acidosis, no brain edema. In the brain, NBCe1 is expressed by astrocytes, where it regulates pH and mediates astrocyte volume changes.
Quinty Bisseling, Mark D. Parker, Sven Kerst, Richard A. Pasternack, Jacob Tondreau, Marjolein Breur, Gemma M. van Rooijen‐van Leeuwen, Davide Tonduti, Ettore Salsano, Alejandra Darling, Joanna A. E. van Wijk, Susanna Törnroth‐Horsefield, Marianna Bugiani, Petra J. W. Pouwels, Quinten Waisfisz, Marjo S. van der Knaap, Rogier Min   +16 more
wiley   +1 more source

Remarkable Recovery After Delayed High‐Dose Methylprednisolone in a Rare Case of Penetrating Spinal Cord Injury

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Traumatic spinal cord injury (TSCI) caused by sharp‐force penetration is exceptionally rare, and the use of high‐dose methylprednisolone (MP) remains highly controversial, especially beyond the conventional 8‐h treatment window. This case report describes a 30‐year‐old male with acute incomplete TSCI following a knife stab wound to the right ...
Honghong Wang, Shuang Liu, Jiale Wang, Kaiyang Xue, Shenwei Li, Zhongheng Du   +5 more
wiley   +1 more source

Material Composition Characteristics of Aspergillus cristatus under High Salt Stress through LC–MS Metabolomics

Molecules
Aspergillus cristatus is a crucial edible fungus used in tea fermentation. In the industrial fermentation process, the fungus experiences a low to high osmotic pressure environment.
Luyi Xie, Lihong Zhou, Rongrong Zhang, Hang Zhou, Yi Yang   +4 more
doaj   +1 more source

The Application of Combined Pre-Treatment with Utilization of Sonication and Reduced Pressure to Accelerate the Osmotic Dehydration Process and Modify the Selected Properties of Cranberries

Foods, 2019
The aim of this study was to investigate the effect of a pretreatment, performed by a combined method based on blanching, ultrasound, and vacuum application, on the kinetics of osmotic dehydration and selected quality properties such as water activity ...
Malgorzata Nowacka, Artur Wiktor, Magdalena Dadan, Katarzyna Rybak, Aleksandra Anuszewska, Lukasz Materek, Dorota Witrowa-Rajchert   +6 more
doaj   +1 more source

Electrochemical Experiment to Evaluate the Impact of Multistage Load and Osmotic Pressure on Anchor Bolt

Geofluids, 2022
In this paper, uniaxial compression tests, multistage loading tests, and electrochemical tests were adopted to investigate the strain characteristics, failure characteristics, and electrochemical impedance of anchor bolts in a cement-gypsum composite ...
Guanglin Sun, Jiangchun Hu, Hongfang Wang, Dewei Li   +3 more
doaj   +1 more source

Experimental study on seepage characteristics of rough fracture of limestone under loading-unloading of confining and osmotic pressures

Yantu gongcheng xuebao, 2023
The influences of the roughness of fracture surface and the loading-unloading environment on seepage characteristics of fracture cannot be ignored. To study the influences of the fracture surface with different joint roughness coefficients (JRC) and ...
GAN Lei, JIN Hongjie, SHEN Zhenzhong, , XU LEI, MA Hongying
doaj   +1 more source

Metabolomics demonstrates divergent responses of two Eucalyptus species to water stress

, 2011
Past studies of water stress in Eucalyptus spp. generally highlighted the role of fewer than five “important” metabolites, whereas recent metabolomic studies on other genera have shown tens of compounds are affected.
Cano, Francisco J. (R18662), Aranda, Ismael, Aranda García, Ismael, Ismael Aranda, Warren, Charles R., Charles R. Warren, F. Javier Cano, Cano Martín, Francisco Javier, Warren, C. R., Cano, F. J.   +9 more
core   +1 more source

Planar Solid‐State Nanopores Toward Scalable Nanofluidic Integration Based on CMOS Technology

Advanced Engineering Materials, EarlyView.
We present a scalable silicon‐based fabrication strategy for planar solid‐state nanopores to enable their integration with complex nanofluidic systems. Prototype devices demonstrate normal voltage‐current characteristics, good noise performance, and appreciable streaming currents. Our CMOS‐compatible fabrication process offers precise geometric control
Ngan Hoang Pham, Chenyu Wen, Mohammad Hadi Khaksaran, Won‐Yong Lee, Javier Cruz, Klas Hjort, Dongping Wu, Shi‐Li Zhang   +7 more
wiley   +1 more source