Results 41 to 50 of about 19,894 (201)

Synostosis Between Pubic Bones due to Neurogenic, Heterotopic Ossification

The Scientific World Journal, 2006
Neurogenic, heterotopic ossification is characterised by the formation of new, extraosseous (ectopic) bone in soft tissue in patients with neurological disorders.
Subramanian Vaidyanathan, Peter L. Hughes, Bakul M. Soni   +2 more
doaj   +1 more source

Clinical Features, Diagnosis and Management of Fibrodysplasia Ossificans Progressiva

罕见病研究, 2023
Fibrodysplasia ossificans progressiva(FOP) is a rare congenital disease characterized by progressive heterotopic ossification, causing severe immobility with multi-system involvement.
ZHAO Junduo, SHEN Jianxiong
doaj   +1 more source

Management of heterotopic ossification affecting both hips and knees. [PDF]

, 2008
The management of heterotopic ossification is controversial. This is a rare case affecting both hips and knees of a 22-year-old woman that prevented her from walking.
Devnani, Anand Sobhraj
core  

Myositis ossificans circumscripta of the buccinator muscle: first report of a rare complication of mandibular third molar extraction. [PDF]

, 2008
Myositis ossificans is a self-limiting ossifying process that most often develops following mechanical trauma to skeletal musculature. It chiefly affects the skeletal muscles of extremities of young athletically active adult males. Myositis ossificans is
Abramovitch, Kenneth, Bouquot, Jerry, Thurber, David, Vigneswaran, Nadarajah, Wiggins, Raymond L   +4 more
core   +1 more source

Dual‐Anchored Clickable Peptide via SPAAC for Gelatinase‐Responsive Antibacterial and Osteogenic Functions on Titanium Implants

Advanced Science, EarlyView.
To address the infection‐associated orthopedic implant failures, this study presents a gelatinase‐responsive antibacterial titanium implant (Ti‐Dual) featuring a dual‐anchored fusion peptide containing antibacterial (HHC36) and osteogenic (RGD) domains connected by a cleavable GPLGV linker.
Ru Zhong, Hang Zhou, Chenyang Ye, Lei Chu, Lin Wang, Yingjun Wang   +5 more
wiley   +1 more source

Late-onset fibrodysplasia ossificans progressiva with atypical presentation: A case report

Case Reports in Women's Health, 2019
Fribrodysplasia ossificans progressiva (FOP) is a rare genetic disease characterized by progressive heterotopic ossification of connective tissues, episodic flare-ups and bilateral deformities of the great toe (hallux valgus).
Conor M. Cunningham, J. Matthew Royeca, Samuel W. King, Hemant Pandit   +3 more
doaj   +1 more source

An unusual case of bowel obstruction in emergency surgery: The heterotopic mesenteric ossification

SAGE Open Medical Case Reports, 2020
The heterotopic mesenteric ossification, also known as myositis ossificans, is a rare form of heterotopic ossification, a metaplastic phenomenon where new bone is formed in the mesenteric base, generally after abdominal trauma (surgical or other).
Ricciardolo Andrea Aurelio, De Ruvo Nicola, Caramaschi Stefani, Serra Francesco, Farinetti Alberto, Mattioli Anna Vittoria, Gelmini Roberta   +6 more
doaj   +1 more source

Mechanical Strain‐Programmed SDC1+ Sheath Fibroblasts Trigger CXCR4hi Neutrophil‐Mediated Enthesitis in Ankylosing Spondylitis

Advanced Science, EarlyView.
In ankylosing spondylitis (AS), mechanical strain‐programmed SDC1+ sheath fibroblasts secrete CXCL5 to recruit neutrophils and promote the activation of CXCR4hi neutrophils, thereby exacerbating enthesitis by promoting neutrophil extracellular traps (NETs) formation. SOX5 controls the generation of SDC1+ sheath fibroblasts via super‐enhancers.
Jiajie Lin, Zepeng Su, Yipeng Zeng, Yi Zhou, Chenying Zeng, Weihao Zhang, Qibo Li, Zipeng Xiao, Zibin Chen, Ziqian Liu, Yangfeng Lin, Guan Zheng, Wenhui Yu, Zhongyu Xie   +13 more
wiley   +1 more source

A new mouse model of post-traumatic joint injury allows to identify the contribution of Gli1+ mesenchymal progenitors in arthrofibrosis and acquired heterotopic endochondral ossification

Frontiers in Cell and Developmental Biology, 2022
Complex injury and open reconstructive surgeries of the knee often lead to joint dysfunction that may alter the normal biomechanics of the joint.
Jenny Magallanes, Jenny Magallanes, Nancy Q. Liu, Jiankang Zhang, Jiankang Zhang, Yuxin Ouyang, Tadiwanashe Mkaratigwa, Tadiwanashe Mkaratigwa, Fangzhou Bian, Fangzhou Bian, Ben Van Handel, Tautis Skorka, Frank A. Petrigliano, Denis Evseenko, Denis Evseenko   +14 more
doaj   +1 more source

Effects of Renal and Hepatic Impairment on the Pharmacokinetics of Zilurgisertib

British Journal of Clinical Pharmacology, EarlyView.
Aim Small‐molecule activin receptor‐like kinase‐2 inhibitor zilurgisertib (INCB000928) is under investigation in a pivotal trial for the treatment of fibrodysplasia ossificans progressiva (FOP), an ultrarare genetic condition. This analysis assessed effects of renal and hepatic impairment on zilurgisertib pharmacokinetics.
Yan‐ou Yang, Yunlan Fang, Phillip Wang, Xiang Liu, Jay Getsy, Kevin Rockich   +5 more
wiley   +1 more source