Results 71 to 80 of about 124,083 (308)

De-ossifying the Internet Transport Layer : A Survey and Future Perspectives [PDF]

open access: yes, 2016
ACKNOWLEDGMENT The authors would like to thank the anonymous reviewers for their useful suggestions and comments.Peer reviewedPublisher ...
Brunstrom, Anna   +10 more
core   +1 more source

Engineering Osteoimmune Responses with Functionalized Orthopedic Implants for Post‐Operative Osteosarcoma Treatment

open access: yesAdvanced Science, EarlyView.
Osteosarcoma is the most common primary bone tumor with limited treatment options and a terrible prognosis. This review provides a comprehensive summary of the recent development of osteoimmunomodulatory implants for post‐operative osteosarcoma treatment, of which the potential utility in evoking durable anti‐osteosarcoma immunity and accelerating bone
Yilong Dong   +6 more
wiley   +1 more source

Diagnostic value of MRI of the sacroiliac joints in juvenile spondyloarthritis [PDF]

open access: yes, 2016
Early diagnosis of spondyloarthritis (SpA) is becoming more important as new medical treatment options have become available to treat inflammation and delay progression of the disease.
Baraliakos, Xenofon   +6 more
core   +1 more source

Single‐Cell Atlas of Subchondral Bone Marrow Lesions Reveals Proteostasis Dysfunction as a Druggable Mechanism for Early Osteoarthritis

open access: yesAdvanced Science, EarlyView.
This study reveals that abnormal mechanical stress downregulates the expression of HSP70 and impairs proteasome function in osteoarthritic bone cells, leading to misfolded collagen I accumulation and ER stress. When intracellular proteostasis capacity is exceeded, USP19 mediates the secretion of misfolded proteins into the extracellular space ...
Hailun Xu   +20 more
wiley   +1 more source

Progression of Spinal Ligament Ossification in Patients with Thoracic Myelopathy

open access: yesOrthopaedic Surgery, 2022
Objective To evaluate the rate of increase in thickness and cross‐section area (CSA) of the ossification in thoracic myelopathy with or without cervical and lumbar spinal ligament ossification.
Jiliang Zhai   +4 more
doaj   +1 more source

Distinct Immunomodulatory Strategies Guide Mesenchymal Stromal/Stem Cell‐Mediated Bone Regeneration

open access: yesAdvanced Science, EarlyView.
Bone regeneration by mesenchymal stem cells is strongly influenced by immune signals. This study shows that priming stem cells with regulatory immune cells or an inflammation‐resolving lipid molecule enhances bone formation through distinct immune pathways.
Salwa Suliman   +5 more
wiley   +1 more source

Loss of ninein interferes with osteoclast formation and causes premature ossification

open access: yeseLife
Ninein is a centrosome protein that has been implicated in microtubule anchorage and centrosome cohesion. Mutations in the human NINEIN gene have been linked to Seckel syndrome and to a rare form of skeletal dysplasia.
Thierry Gilbert   +13 more
doaj   +1 more source

Clinical and radiologic results of surgicallytreated acetabular fractures

open access: yesActa Orthopaedica et Traumatologica Turcica, 2021
Objectives: We evaluated the functional and radiologic results of surgical treatment in patients with displaced acetabular fractures.\nMethods: The study included 21 patients (13 males, 8 females; mean age 35 years; range 21 to 63 years). Before surgery,
Nurzat Elmali   +4 more
doaj  

New Spontaneous Model of Fibrodysplasia Ossificans Progressiva [PDF]

open access: yes, 2008
We report the first known example of spontaneous, naturally occurring fibrodysplasia ossificans progressiva (FOP) in a mammal. The Southeast Asian mouse deer of the genus _Tragulus_ (Artiodactyla: Tragulidae) have an osseous sheath covering the lower ...
Bruce Rothschild   +2 more
core   +1 more source

Quantitative geometric analysis of rib, costal cartilage and sternum from childhood to teenagehood [PDF]

open access: yes, 2013
Better understanding of the effects of growth on children’s bones and cartilage is necessary for clinical and biomechanical purposes. The aim of this study is to define the 3D geometry of children’s rib cages: including sternum, ribs and costal cartilage.
BADINA, Alina   +5 more
core   +4 more sources

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