Results 81 to 90 of about 1,135 (163)

Fungal keratitis with topical interferon-α2b in ocular surface squamous neoplasia

Journal of Clinical Ophthalmology and Research
This report highlights a unique case of fungal keratitis following the use of topical interferon alpha-2b (IFN-α2b) for managing ocular surface squamous neoplasia (OSSN).
Neha Jain, Dharma Sanandiya, Vikas Mittal   +2 more
doaj   +1 more source

Diagnosis and medical management of ocular surface squamous neoplasia

, 2017
Introduction: Topical chemotherapy has gained popularity among clinicians for the treatment of ocular surface squamous neoplasia (OSSN) . The principal topical chemotherapy agents used in the management of OSSN are interferon-α2b, 5-fluorouracil, and ...
Palioura, Sotiria, Galor, Anat, Sayed-Ahmed, Ibrahim O, Karp, Carol L   +3 more
core   +1 more source

An update in the management of ocular surface squamous neoplasia

, 2021
Management of ocular surface squamous neoplasia (OSSN) has been a matter of debate among ocular oncologists. While surgical excision with tissue biopsy has been the gold standard, topical chemotherapy with agents such as interferon-α2b, 5-fluorouracil ...
Kounatidou, Nefeli Eleni, Palioura, Sotiria   +1 more
core   +1 more source

Prevalence and genotypes of HPV in pre-invasive ocular surface squamous neoplasia in Pretoria

African Vision and Eye Health
Background: Pre-invasive ocular surface squamous neoplasia (OSSN) are tumours of the ocular surface that include squamous neoplasms arising from the conjunctiva and the cornea, characterised by a multifactorial aetiopathogenesis.
Lucia N. Mhlongo, Moshawa C. Khaba, Ramokone L. Lebelo, Cornelius M. Nkosi   +3 more
doaj   +1 more source

Ocular Surface Squamous Neoplasia (OSSN) Risk Factors in Lusaka, Zambia: The Role of HIV and Socioeconomic Status [PDF]

Objective To identify and evaluate potential risk factors for OSSN at the University Teaching Hospital (UTH) in Lusaka, Zambia. Methods Data from 475 patients were analyzed retrospectively, and it included 390 with OSSN and 85 with benign biopsies ...
Mengist, Abraham, Wood, Charles, Siyumbwa, Stepfanie N, Chilyabanyama, Obvious N., Haynatzki, Gleb, Julius, Peter, Nkhata, Tabitha   +6 more
core  

Accuracy of diagnosing early ocular surface squamous neoplasia using methylene blue in Zambia

African Vision and Eye Health
Background: Ocular surface squamous neoplasia (OSSN) includes pre-invasive and invasive squamous lesions of the ocular surface. Current diagnosis relies on surgical excision and histology, with potential complications. This study assessed the reliability
Amogelang Morapelo, Peter D. Julius, Elijah M. Munachonga, Stepfanie N. Siyumbwa, Phyllis Moonga   +4 more
doaj   +1 more source

Comparative Evaluation of Topical Mitomycin‑C versus Interferon‑α2b in the Management of Ocular Surface Squamous Neoplasia (OSSN)

Background To compare the efficacy, safety, and clinical outcomes of topical interferon-α2b (IFN-α2b) and mitomycin C (MMC) in primary ocular surface squamous neoplasia (OSSN).
Niraj Kumar Yadav, Alisha Dua, Amol Singh Garcha   +2 more
core   +1 more source

Electron beam radiotherapy for the management of recurrent extensive ocular surface squamous neoplasia with orbital extension

Indian Journal of Ophthalmology, 2015
Recurrent extensive ocular surface squamous neoplasia (OSSN) with orbital invasion can be successfully managed with external radiotherapy using electrons resulting in eye and vision salvage.
Ramesh Murthy, Himika Gupta, Rahul Krishnatry, Siddhartha Laskar   +3 more
doaj   +1 more source

Comparison of Topical 5-Fluorouracil and Interferon Alfa-2b as Primary Treatment Modalities for Ocular Surface Squamous Neoplasia

, 2019
To compare the efficacy of topical 5-fluorouracil 1% (5FU) and interferon alfa-2b 1 MIU/mL (IFN) eye drops as primary treatment modalities for ocular surface squamous neoplasia (OSSN). Retrospective, comparative, interventional case series.
Venkateswaran, Nandini, Galor, Anat, Karp, Carol L, Mercado, Carolina   +3 more
core   +1 more source

Predictors of Ocular Surface Squamous Neoplasia and Conjunctival Squamous Cell Carcinoma among Ugandan Patients: A Hospital-based Study. [PDF]

, 2019
AIM: The aim of the study was to assess the predictors of ocular surface squamous neoplasia (OSSN) and conjunctival squamous cell carcinoma (SCC) among Ugandan patients.
Lloyd, Harrison-Williams CM, Arunga, Simon, Twinamasiko, Amos, Onyango, John, Frederick, Meier A   +4 more
core   +1 more source