Results 41 to 50 of about 3,683 (200)

Vitamin D Deficiency and the Presentation of Primary Hyperparathyroidism: A Mini Review

International Journal of Endocrinology, Volume 2023, Issue 1, 2023., 2023
The clinical presentation of primary hyperparathyroidism (PHPT) has evolved over the years from a symptomatic disorder to a predominantly asymptomatic condition. Altered vitamin D metabolism seems to play a role in the presentation of PHPT and may exacerbate the severity of disease.
Niharika Yedla, Hyon Kim, Anupa Sharma, Xiangbing Wang, Jaya   +4 more
wiley   +1 more source

Three Malagasy Cases of Severe Bone Complications Revealing Primary Hyperparathyroidism. [PDF]

Case Rep Endocrinol
Primary hyperparathyroidism (PHPT) is a metabolic disorder characterized by hypercalcemia with elevated or unsuppressed parathyroid hormone (PTH). It is rare in children but common in adults, particularly in women around the age of 50. In 85% of cases, PHPT is asymptomatic and is diagnosed following hypercalcemia and elevated PTH levels during routine ...
Andrianadison Z, Rakotonirina LN, Rakotonirainy OH, Andrianiaina MO, Rakotomahefa MNL, Rapelanoro Rabenja F.   +5 more
europepmc   +2 more sources

Femoral Neck Fracture in a Pediatric Patient with Primary Hyperparathyroidism

Case Reports in Orthopedics, Volume 2023, Issue 1, 2023., 2023
Case. A previously healthy 11‐year‐old girl underwent expedited surgical fixation of a femoral neck fracture sustained while jump‐roping. After further work up, she was diagnosed with primary hyperparathyroidism. Parathyroidectomy of a hypertrophic adenoma proved curative.
Mark W. Schmitt, Maxwell J. Modrak, Soumar J. Bouza, Brian G. Smith, Murillo A. Adrados, Akio Sakamoto   +5 more
wiley   +1 more source

A Rare Presentation of a Bi‐Maxillary Brown Tumour due to Secondary Hyperparathyroidism

Case Reports in Dentistry, Volume 2023, Issue 1, 2023., 2023
Brown tumours are localized bone lesions, seen in patients with high parathyroid hormone levels. This can be due to primary hyperparathyroidism, which occurs more often in neoplasms of the parathyroid gland or due to secondary hyperparathyroidism more often seen as a result of renal impairment.
Cheboh Cho-Fon, Zilefac Brian Ngokwe, Obolo Nwaga Ines, Rui Amaral Mendes   +3 more
wiley   +1 more source

Hypopituitarism due to a Large Osteoclastoma Arising from the Sphenoid Bone Invading the Pituitary Fossa in a Patient with Parathyroid Carcinoma

Case Reports in Endocrinology, Volume 2023, Issue 1, 2023., 2023
Background. Parathyroid carcinoma accounts for <1% of cases of primary hyperparathyroidism (PHPT). This rare condition may present with severe hypercalcemia and bone complications such as osteoclastomas and pathologic fractures. Here, we present a rare condition of panhypopituitarism resulting from an osteoclastoma in the sphenoid bone that invaded the
Leonardo Bandeira, Lucian Batista de Oliveira, Maria Vitória Silva de Lima, Daniella Rêgo, Luiz Griz, Francisco Bandeira, Toshihiro Kita   +6 more
wiley   +1 more source

Evaluation and Management of Primary Hyperparathyroidism: Summary Statement and Guidelines from the Fifth International Workshop

Journal of Bone and Mineral Research, Volume 37, Issue 11, Page 2293-2314, November 2022., 2022
ABSTRACT The last international guidelines on the evaluation and management of primary hyperparathyroidism (PHPT) were published in 2014. Research since that time has led to new insights into epidemiology, pathophysiology, diagnosis, measurements, genetics, outcomes, presentations, new imaging modalities, target and other organ systems, pregnancy ...
John P. Bilezikian, Aliya A. Khan, Shonni J. Silverberg, Ghada El‐Hajj Fuleihan, Claudio Marcocci, Salvatore Minisola, Nancy Perrier, Antonio Sitges‐Serra, Rajesh V. Thakker, Gordon Guyatt, Michael Mannstadt, John T. Potts, Bart L. Clarke, Maria Luisa Brandi, On behalf of the International Workshop on Primary Hyperparathyroidism   +14 more
wiley   +1 more source

Spinal cord compression secondary to brown tumour in a patient on long-term haemodialysis: a case report. [PDF]

, 2009
Brown tumours may occur secondary to hyperparathyroidism in patients with chronic renal failure (CRF). Diagnosing a spinal brown tumour causing cord compression requires a high index of suspicion.
Luk, KD, Mak, KC, Wong, YW
core   +1 more source

Classical and Nonclassical Manifestations of Primary Hyperparathyroidism

Journal of Bone and Mineral Research, Volume 37, Issue 11, Page 2330-2350, November 2022., 2022
ABSTRACT This narrative review summarizes data on classical and nonclassical manifestations of primary hyperparathyroidism (PHPT). It is based on a rigorous literature search, inclusive of a Medline search for systematic reviews from 1940 to December 2020, coupled with a targeted search for original publications, covering four databases, from January ...
Ghada El‐Hajj Fuleihan, Marlene Chakhtoura, Cristiana Cipriani, Richard Eastell, Tatiana Karonova, Jian‐Min Liu, Salvatore Minisola, Ambrish Mithal, Carolina A Moreira, Munro Peacock, Marian Schini, Barbara Silva, Marcella Walker, Ola El Zein, Claudio Marcocci   +14 more
wiley   +1 more source

Serum parathyroid hormone levels and renal handling of phosphorus in patients with chronic renal disease [PDF]

, 1972
In eight patients with advanced renal insufficiency (inulin clearance 1.4-9.1 ml/min), concentrations of serum calcium (S[Ca]) and phosphorus (S[P]) were maintained normal (S[Ca] > 9.0 mg/100 ml, (S[P] < 3.5 mg/100 ml) for at least 20 consecutive days ...
Halgrimson, CG, Hutt, MP, Pinggera, WF, Popovtzer, MM, Robinette, J, Starzl, TE   +5 more
core   +1 more source

The Efficacy and Safety of Medical and Surgical Therapy in Patients With Primary Hyperparathyroidism: A Systematic Review and Meta‐Analysis of Randomized Controlled Trials

Journal of Bone and Mineral Research, Volume 37, Issue 11, Page 2351-2372, November 2022., 2022
ABSTRACT Both medical and surgical therapy represent potential management options for patients with asymptomatic primary hyperparathyroidism (PHPT). Because uncertainty remains regarding both medical and surgical therapy, this systematic review addresses the efficacy and safety of medical therapy in asymptomatic patients or symptomatic patients who ...
Zhikang Ye, Shonni J. Silverberg, Ashwini Sreekanta, Kyle Tong, Ying Wang, Yaping Chang, Mengmeng Zhang, Gordon Guyatt, Wimonchat Tangamornsuksun, Yi Zhang, Veena Manja, Layla Bakaa, Rachel J. Couban, Maria Luisa Brandi, Bart Clarke, Aliya A. Khan, Michael Mannstadt, John P. Bilezikian   +17 more
wiley   +1 more source