Results 81 to 90 of about 218,046 (303)

GAMBARAN KUALITAS HIDUP DAN TINGKAT KECEMASAN PASIEN OSTEOARTRITIS LUTUT DI INSTALASI REHABILITASI MEDIK RSUP DR. KARIADI SEMARANG [PDF]

, 2015
Background: The incidence of osteoarthritis increases with age and become major cause of disability among the elderly. The prevalence of osteoarthritis knee is quite high in Indonesia, especially in Semarang city and the effect on quality of life and ...
Hafizh, Muhammad, Tanti Ajoe, Kesoema
core  

Stable sulforaphane protects against gait anomalies and modifies bone microarchitecture in the spontaneous STR/Ort model of osteoarthritis [PDF]

, 2017
Osteoarthritis (OA), affecting joints and bone, causes physical gait disability with huge socio-economic burden; treatment remains palliative. Roles for antioxidants in protecting against such chronic disorders have been examined previously. Sulforaphane
Ahmed Aljazzar, Alam, Andrea Pollard, Andrew A. Pitsillides, Behzad Javaheri, Bellido, Blandine Poulet, Boris Chan, Brewster, Carbone, Castañeda, Chambers, Chambers, Chiusaroli, Christiansen, Clarke, Conaghan, Custers, Davidson, Davidson, Doube, Duarte, Elaine Shervill, Foster, Glasson, Glasson, Goldring, Goldring, Haseeb, Hayami, Henrotin, Ho, Hochman, Isabel R. Orriss, Javaheri, Javaheri, Juge, Juhl, Karsdal, Kim, Li, Little, Lo, Mark Hopkinson, Mason, Miriam Piles, Mündermann, Pasold, Pastoureau, Pauli, Pearson, Peter D. Lee, Piles, Poulet, Poulet, Poulet, Poulet, Poulet, Pritzker, Radin, Roberto de Souza, Scheller, Schnitzer, Tat, Taylor, Thaler, Uchida, Valdes, Vincelette, Wang, Wu, Xiao, Yu-Mei Chang, Zakkar   +73 more
core   +3 more sources

Injectable Dual‐Network Hydrogel System for Osteochondral Repair Combining Immunomodulation, Mechanical Adaptability, and Enhanced Tissue Integration

Advanced Functional Materials, EarlyView.
A UV‐triggered injectable dual‐network hydrogel is reported as the first application of bletilla striata polysaccharide (BSP) in osteochondral repair. By integrating methacrylamide‐modified BSP and nitrobenzaldehyde‐functionalized hyaluronic acid, the system achieves immunomodulation, mechanical reinforcement, and dynamic tissue adhesion, thereby ...
Jiaming Cui, Feifei Zhou, Yuan Luo, Tao Ouyang, Huiwu Zhang, Songmiao Cheng, Qiang Li, Xu Jiang, Yingying Yu, Yicheng Wang, Hong Ming   +10 more
wiley   +1 more source

Effectiveness of behaviour change techniques in physiotherapy interventions to promote physical activity adherence in lower limb osteoarthritis patients: A systematic review [PDF]

, 2019
Background: Lower limb osteoarthritis (OA) causes high levels of individual pain and disability and is an increasing socio-economic burden to global healthcare systems.
Duda, Joan, Fenton, Sally, Gautrey, Charlotte, Greig, Carolyn, Rushton, Alison, Willett, Matthew   +5 more
core   +4 more sources

Mesenchymal Stem Cell‐Derived Apoptotic Micro‐Vesicles Repaired Sciatic Nerve Defect by Regulating Early Inflammatory Microenvironment and Promoting Angiogenesis

Advanced Healthcare Materials, EarlyView.
HUCMSC‐Apo‐mvs enhance peripheral nerve repair by modulating the inflammatory microenvironment (IME), primarily through coordinated actions on three functional cells. They recruit macrophages and promote their polarization from pro‐inflammatory M1 to anti‐inflammatory M2 phenotypes, increasing secretion of IL‐10 and VEGF.
Haolin Liu, Yiben Ouyang, Bo Wang, Xiaochun Zhang, Yanjun Guan, Ruichao He, Yuhui Cui, Junli Wang, Qianru Yao, Yixiao Tan, Xiwei Peng, Xing Xiong, Sice Wang, Dongdong Li, Haofeng Cheng, Tianqi Su, Xiaoyang Fu, Jinjuan Zhao, Mingqian Yu, Yi Wang, Jiang Peng, Yu Wang   +21 more
wiley   +1 more source

Knee osteoarthritis treatment

Medicinski pregled, 2022
Introduction. Osteoarthritis is the most common form of arthritis which affects millions of people worldwide and represents the leading cause of disability among the elderly. There is a substantial number of guidelines available for the treatment of knee osteoarthritis.
Aleksandar Knezevic, Larisa Vojnovic, Dunja Popovic, Tijana Spasojevic, Enis Garipi   +4 more
openaire   +1 more source

A Synovium‐on‐Chip Platform to Study Multicellular Interactions in Arthritis

Advanced Healthcare Materials, EarlyView.
The Synovium‐on‐Chip comprises a thin microporous PDMS membrane to support co‐culture of fibroblast‐like synoviocytes (FLS), THP‐1‐derived macrophages, and endothelial cells, enabling real‐time analysis of synovial‐vascular interactions. FLS migration through the pores drives endothelial remodeling, while TNF‐α stimulation induces robust inflammatory ...
Laurens R. Spoelstra, Fleur R. Semmekrot, Nuno Araújo‐Gomes, Daniël Wijnperle, Monique M. A. Helsen, Martijn H.J. Van Den Bosch, Loes. I. Segerink, Séverine Le Gac, Marcel Karperien   +8 more
wiley   +1 more source

Update in exploring the connection and clinical implications between vitamin D and knee osteoarthritis [PDF]

Balneo and PRM Research Journal
Knee osteoarthritis is a prevalent joint disorder characterized by cartilage degeneration, pain, and impaired physical function. Vitamin D might be implicated in the management of knee osteoarthritis through its effects on bone health, cartilage ...
Bianca Georgescu, Doinița Oprea, Bogdan-Alexandru Georgescu, Cristina-Mădălina Lungu, Erdin Borgazi, Mădălina-Gabriela Iliescu   +5 more
doaj   +1 more source

The role of adipose-derived mesenchymal stem cells in knee osteoarthritis: a meta-analysis of randomized controlled trials

Therapeutic Advances in Musculoskeletal Disease, 2022
Background: Adipose-derived mesenchymal stem cells (ADMSCs) have recently been studied for the treatment of knee osteoarthritis. The goal is pain reduction and improvement of joint function leading to superior health-related quality of life.
Mohamad R. Issa, Ahmad S. Naja, Nour Z. Bouji, Bernard H. Sagherian   +3 more
doaj   +1 more source

Biomechanical factors associated with the development of tibiofemoral knee osteoarthritis: protocol for a systematic review and meta-analysis [PDF]

, 2016
INTRODUCTION: Altered biomechanics, increased joint loading and tissue damage, might be related in a vicious cycle within the development of knee osteoarthritis (KOA).
Dekker, Joost, Dell'Isola, Andrea, Juhl, Carsten, Lund, Hans, Steultjens, Martijn, van Tunen, Joyce A.C.   +5 more
core   +5 more sources