Results 81 to 90 of about 207,929 (303)

Knee Osteoarthritis: A Primer [PDF]

The Permanente Journal, 2017
The purpose of this article is to provide a synopsis of the current medical understanding of knee osteoarthritis. We describe the prevalence, causes and associated risk factors, symptoms, diagnosis and classification, and treatment options. A quiz serves to assist readers in their understanding of the presented material.
George F. Muschler, Michael A. Mont, Nicolas S. Piuzzi, Guarino A, Husni Me, Michelle J Lespasio   +5 more
openaire   +3 more sources

Biomaterial Strategies for Targeted Intracellular Delivery to Phagocytes

Advanced Functional Materials, EarlyView.
Phagocytes are essential to a functional immune system, and their behavior defines disease outcomes. Engineered particles offer a strategic opportunity to target phagocytes, harnessing inflammatory modulation in disease. By tuning features like size, shape, and surface, these systems can modulate immune responses and improve targeted treatment for a ...
Kaitlyn E. Woodworth, Neal I. Callaghan, Locke Davenport Huyer   +2 more
wiley   +1 more source

Smoothness of the knee joint movement during the stance phase in patients with severe knee osteoarthritis

Asia-Pacific Journal of Sports Medicine, Arthroscopy, Rehabilitation and Technology, 2018
Background: Patients with knee osteoarthritis can significantly affect the function of the knee joint in terms of joint range and mobility and have a stereotypical pattern of knee stiffness during gait, caused by an increased resistance in the muscles ...
Takashi Fukaya, Hirotaka Mutsuzaki, Wataru Nakano, Koichi Mori   +3 more
doaj   +1 more source

Effectiveness of behaviour change techniques in physiotherapy interventions to promote physical activity adherence in lower limb osteoarthritis patients: A systematic review [PDF]

, 2019
Background: Lower limb osteoarthritis (OA) causes high levels of individual pain and disability and is an increasing socio-economic burden to global healthcare systems.
Duda, Joan, Fenton, Sally, Gautrey, Charlotte, Greig, Carolyn, Rushton, Alison, Willett, Matthew   +5 more
core   +4 more sources

Smart, Bio‐Inspired Polymers and Bio‐Based Molecules Modified by Zwitterionic Motifs to Design Next‐Generation Materials for Medical Applications

Advanced Functional Materials, EarlyView.
Bio‐based and (semi‐)synthetic zwitterion‐modified novel materials and fully synthetic next‐generation alternatives show the importance of material design for different biomedical applications. The zwitterionic character affects the physiochemical behavior of the material and deepens the understanding of chemical interaction mechanisms within the ...
Theresa M. Lutz, Jonas De Breuck, Sahar Salehi, Meike N. Leiske   +3 more
wiley   +1 more source

Effect of Romosozumab Treatment in Postmenopausal Women With Osteoporosis and Knee Osteoarthritis: Results From a Substudy of a Phase 3 Clinical Trial

ACR Open Rheumatology
Objective Romosozumab is a bone‐forming agent approved for osteoporosis treatment. Here we report results of the protocol‐specified, noninferiority osteoarthritis substudy of the fracture study in postmenopausal women with osteoporosis (FRAME), which ...
Nancy E. Lane, Donald Betah, Cynthia Deignan, Mary Oates, Zhenxun Wang, Jen Timoshanko, Aliya A. Khan, Neil Binkley   +7 more
doaj   +1 more source

Bioassembly of Region‐Specific Fibrocartilage Microtissues to Engineer Zonally Defined Meniscal Grafts

Advanced Healthcare Materials, EarlyView.
Meniscal microtissues are fabricated using progenitor cells isolated from the inner (iMPCs) and outer (oMPCs) regions of the meniscus. Meniscal microtissues fuse into cohesive constructs rich in sGAG and collagen. cABC treatment modulates collagen fiber formation and organization in assembled grafts.
Gabriela S. Kronemberger, Kaoutar Chattahy, Francesca D. Spagnuolo, Aliaa S. Karam, Daniel J. Kelly   +4 more
wiley   +1 more source

Conducting Polymer Coatings for Bioelectronic Arthroscopy Probes

Advanced Healthcare Materials, EarlyView.
Schematic of a poly(3,4‐ethylenedioxythiophene, PEDOT)‐coated arthroscopy probe, featuring a semi‐spherical probe with 38 microelectrodes, used to measure streaming potential generated during cartilage indentation in the knee. The inset includes a scanning electron microscopy (SEM) image of the porous PEDOT layer deposited on a nickel‐phosphorus coated
Sara Ebrahimi, Sadaf Khoomortezaei, Jiaxin Fan, Kathel Dongnang, Martin Garon, Eric Quenneville, Fabio Cicoira   +6 more
wiley   +1 more source

Weight, height, waist circumference: association with knee osteoarthritis findings from the osteoarthritis initiative

PAIN Reports
. Introduction:. Global prevalence of knee osteoarthritis is more than 300 million. Uncontrollable risk factors include age, sex, and height. Controllable risk factors include trauma, weight, and waist circumference. Objectives:.
Lisa H. Antoine, Kristen Allen Watts, Deanna D. Rumble, Taylor Buchanan, Andrew Sims, Burel R. Goodin   +5 more
doaj   +1 more source

Decision-making regarding total knee replacement surgery: a qualitative meta-synthesis [PDF]

, 2007
Knee osteoarthritis is a highly prevalent condition that can result in disability and reduced quality of life. The evidence suggests that total knee replacement surgery (TKR) is an effective intervention for patients with severe knee problems, but there ...
Jinks, C, O'Neill, T, Ong, BN
core   +3 more sources