Results 91 to 100 of about 105,951 (266)

Liposomal Delivery of L‐2‐Hydroxyglutarate for Targeting Epigenetic Dysregulation in Osteoarthritis

Advanced NanoBiomed Research, EarlyView.
Osteoarthritis involves cartilage degeneration, inflammation, and epigenetic dysregulation. A liposomal formulation of the TET1 inhibitor L‐2‐hydroxyglutarate to overcome rapid joint clearance was developed. The formulation showed good physicochemical properties, reduced inflammatory and catabolic gene expression in chondrocytes, and alleviated ...
Denise Murgia, Akshay Pandey, Raffaele Spanò, Bianca Martins Estevão, Roberto Palomba, Greta Avancini, Tamaghna Gupta, Ana Maria Lopez Estevez, Stuart B. Goodman, Nidhi Bhutani, Paolo Decuzzi   +10 more
wiley   +1 more source

STRIDE LENGTH AND ITS CORRELATION WITH DYNAMIC BALANCE IN THE ELDERLY WITH KNEE OSTEOARTHRITIS

Journal of Vocational Health Studies
Background: Patients with knee osteoarthritis experience postural changes that impair balance control due to frequent shifts in the Center of Gravity (COG). Individuals who experience knee osteoarthritis tend to experience a decrease in stride length.
Nikmatur Rosidah, Raray Inas Prianggalistiari, Anita Faradilla Rahim, Bayu Prastowo   +3 more
doaj   +1 more source

Continuous Sewing Machine‐Like Suture Provides Higher Failure and Yield Load Compared to Traditional Techniques for Meniscal Root Repair in a Biomechanical Porcine Model

Arthroscopy, EarlyView.
Purpose To evaluate the biomechanical performance of the sewing machine‐like suture (SMS) technique against three established techniques (two cinch‐loop (TCL), modified Mason‐Allen (MMA), and double Mason‐Allen (DMA)) for transtibial pull‐out repair of posterior medial meniscal root tear (PMMRT) in a porcine model.
Yizhong Peng, Wenbo Yang, Yi Li, Chunqing Meng, Hong Wang, Wei Huang   +5 more
wiley   +1 more source

Nontobacco Nicotine Dependence Is Associated With Perioperative Complications and Repeat Surgery After Arthroscopic Rotator Cuff Repair

Arthroscopy, EarlyView.
Purpose To compare perioperative complications and revision surgery rates between following primary rotator cuff repair among patients with nontobacco nicotine dependence (NTND), no nicotine dependence, and traditional tobacco‐related nicotine dependence.
Samuel A. Florentino, Alexander N. Berk, Logan M. Good, Jeremy M. Adelstein, Robert J. Wetzel, George Ochenjele, Joshua K. Napora   +6 more
wiley   +1 more source

Quantitative ultrasound assessment of gastrocnemius muscle changes in patients with knee osteoarthritis

Journal of International Medical Research
Background Knee osteoarthritis presents with posterior knee pain, stiffness, and restricted mobility, potentially affecting periarticular muscle biomechanics.
Hui Zuo, Ting Xu, Qianwen Wang, Wei Tan, Xu Liu   +4 more
doaj   +1 more source

Whole-body water mass and osteoarthritis: a Mendelian randomization study

Archives of Medical Science
Introduction This study aimed to elucidate the potential impact of whole-body water mass on osteoarthritis at the genetic prediction level through a two-sample Mendelian randomization (MR) analysis.
Qi Qu, Rui Jiang, Yizhou Chen, Zheng Zhang, Wensheng Zhu   +4 more
doaj   +1 more source

Healing Integrity Determines Meniscal Extrusion After Isolated Medial Meniscus Posterior Root Repair in Knees With No Lower Limb Malalignment

Arthroscopy, EarlyView.
Purpose To investigate changes in meniscal extrusion and meniscal healing status following root repair, and the relationship between meniscal extrusion and healing conditions. Methods Patients who underwent isolated root repair between 2019 and 2023 and consented to undergo second‐look arthroscopy to evaluate their healing condition (1 year ...
Jin Seong Kim, Ui Jae Hwang, Chang Woo Woo, Choong Hyeok Choi, Kyu Sung Chung   +4 more
wiley   +1 more source

Machine learning and deep neural network-based learning in osteoarthritis knee. [PDF]

World J Methodol, 2023
Ratna HVK, Jeyaraman M, Jeyaraman N, Nallakumarasamy A, Sharma S, Khanna M, Gupta A.   +6 more
europepmc   +1 more source

Exercise for osteoarthritis of the knee

Cochrane Database of Systematic Reviews
Knee osteoarthritis (OA) is a major public health issue causing chronic pain, impaired physical function, and reduced quality of life. As there is no cure, self-management of symptoms via exercise is recommended by all current international clinical guidelines.
Lawford, BJ, Hall, M, Hinman, RS, Van der Esch, M, Harmer, AR, Spiers, L, Kimp, A, Dell'Isola, A, Bennell, KL   +8 more
openaire   +3 more sources

Computed Tomography‐Based Morphometric Analysis Reveals Intercondylar Notch Stenosis and Osteophytes Are Associated With Anterior Cruciate Ligament Injury

Arthroscopy, EarlyView.
Purpose To quantitatively assess intercondylar notch morphometrics using 3‐dimensional computed tomography reconstruction, evaluate their association with anterior cruciate ligament (ACL) injury in Asian populations, and investigate the prevalence of osteophytes in patients with ACL injury.
Xiaozhong Ma, WenMing Jiang, Chao Lu, Tongyue Ji, Su Yan, Heng Zhu, Xue He, Hao Shu, Lei Wang, Luning Sun   +9 more
wiley   +1 more source