Results 81 to 90 of about 145,230 (316)

Economic evaluation of a rehabilitation program integrating exercise, self-management, and active coping strategies for chronic knee pain [PDF]

, 2007
OBJECTIVE: To conduct an economic evaluation of the Enabling Self-Management and Coping with Arthritic Knee Pain through Exercise (ESCAPE-knee pain) program.
Jones, R. H., Williamson, Elizabeth, Pimm, T.J., Mitchell, H. L., Dieppe, P. A., Walsh, NE, Pimm, TJ, Mitchell, Helene, Patel, A., Dieppe, PA, Hurley, Mike, Jones, R.H., Hurley, MV, Walsh, N. E., Reeves, BC, Mitchell, H., Dieppe, P.A., Jones, RH, Dieppe, Paul, Hurley, Michael, Pimm, T. J., Hurley, M. V., Walsh, N.E., Pimm, J, Patel, Anita, Patel, A, Reeves, Barney, Walsh, Nicola, Williamson, E, Jones, Roger, Mitchell, H.L., Reeves, B. C., Mitchell, HL, Williamson, E., Reeves, B.C., Pimm, John   +35 more
core   +1 more source

Interface‐Engineered Binary Framework Composites: Advancing Porous Materials for Precision Medicine

Advanced Materials Interfaces, EarlyView.
Binary framework composites integrate two complementary porous architectures into a unified platform, enabling multifunctional design, enhanced structural tunability, and improved physicochemical performance. By combining high surface area, ordered porosity, interfacial synergy, and versatile functionalization, these hybrid materials offer new ...
Navid Rabiee, Mohammad Rabiee, Mohammad Akrami‐Hasan‐Kohal, Sidi A. Bencherif   +3 more
wiley   +1 more source

The ligamentum mucosum’s potential as a preventative structure in the development of knee osteoarthritis

Journal of Experimental Orthopaedics, 2023
Purpose This paper aimed to identify whether the presence, type, and/or morphology of the ligamentum mucosum could play a role in the development of knee osteoarthritis.
Alexandra Martin, Kenneth Liu, Majid Alimohammadi   +2 more
doaj   +1 more source

Piezo2 Mediates a Vicious Cycle of “Mechanical Homeostasis Imbalance—Inflammation” in Sensory Nerves and the Cartilage Endplate

Advanced Science, EarlyView.
In a lumbar spine instability model, dorsal root ganglion cells mediate the perception of relevant mechanical stresses through Piezo2 and subsequently release CGRP. CGRP activates the NF‐κB signaling pathway in cartilage endplate cells through the receptor RAMP1.
Hanpeng Xu, Wen Geng, Zhi Du, Yifan Du, Di Wu, Bide Tong, Huaizhen Liang, Xingyu Zhou, Zixuan Ou, Junyu Wei, Kun Wang, Yu Song, Wenbin Hua, Yan Xu, Wencan Ke, Bingjin Wang, Cao Yang   +16 more
wiley   +1 more source

Self‐Assembling Hybrid Hydrogel Reprograms the Stromal Vascular Fraction to Treat Osteoarthritis

Advanced Science, EarlyView.
This study presents a bioinspired injectable hydrogel that enhances the therapeutic potential of stem cell‐rich stromal vascular fraction for treating osteoarthritis. By reprogramming cell behavior through epigenetic modulation, the hydrogel promotes cartilage regeneration and reduces joint damage in a rat model, offering a promising new approach for ...
Waifang Hou, Yongfeng Chen, Longyou Xiao, Wei Qi, Tianshu Du, Qiang Sun, Borui Xue, Qinghe Zhao, Pengfei Xie, Zi Ye, Fei Han, Lingli Guo, Yang Jiao, Ranran Zhang, Hong Jia, Xiao Huang, Jianwei Guo, Peng Wang, Huayi Wang, Yuanrui Wang, Wenjing Chen, Haining Wu, Liumin He, Dawei Zhang   +23 more
wiley   +1 more source

Lower Income and Nonheterosexual Orientation Are Associated With Poor Access to Care in Patients With Knee Osteoarthritis

Arthroplasty Today
Background: Social determinants of health are implicated in the experience of knee osteoarthritis, a key component of which is access to care and healthcare utilization.
Sayi P. Boddu, BA, Vikram S. Gill, BS, Jack M. Haglin, MD, Joseph C. Brinkman, MD, David G. Deckey, MD, Joshua S. Bingham, MD   +5 more
doaj   +1 more source

Health beliefs before and after participation on an exercised-based rehabilitation programme for chronic knee pain: doing is believing [PDF]

, 2010
BACKGROUND: To explore the health beliefs, experiences, treatment and expectations of people with chronic knee pain, and investigate if, how and why these change after taking part on an integrated exercise-based rehabilitation programme--Enabling Self ...
Bhavnani, Vanita, Stevenson Fiona, Stevenson, Fiona, Fiona Stevenson, Hurley, Michael V., Bhavnani Vanita, Britten Nicky, Walsh, Nicola, Bhavnani, V, Vanita Bhavnani, Walsh, N, Britten, N, Hurley, MV, Nicky Britten, Stevenson, F, Hurley Michael V, Britten, Nicky, Walsh Nicola, Hurley, Michael V, Nicola Walsh, Michael V Hurley   +20 more
core   +1 more source

Disruption of Treg Homeostasis in Rheumatoid Arthritis via Ferroptosis‐Mediated ETC Collapse and TXK‐STAT3/PLCγ1 Activation

Advanced Science, EarlyView.
In rheumatoid arthritis, synovial Tregs accumulate but are functionally impaired due to iron overload‐induced ferroptosis. This triggers mitochondrial dysfunction and TXK tyrosine kinase‐mediated signaling, leading to Treg destabilization and inflammation.
Jingrong Chen, Xiao Guan, Kexu Xiong, Xiaoyi Shi, Luyao Wu, Chuanxin Su, Jun Zhao, Rongzhen Liang, Huimin Wang, Junlong Dang, Ye Chen, Yiding Xiong, Chi Zhou, Futao Zhao, Zhenhang Zhu, Xiaoli Fan, Li Zhou, Nancy Olsen, Yutong Jiang, Song Guo Zheng   +19 more
wiley   +1 more source

The association between toe grip strength and osteoarthritis of the knee in Japanese women: A multicenter cross-sectional study. [PDF]

PLoS ONE, 2017
We evaluated the relationship between altered foot function and knee osteoarthritis through a specific comparison of toe grip strength in older women with and without knee osteoarthritis.
Daisuke Uritani, Takahiko Fukumoto, Tomoki Myodo, Kazuhito Fujikawa, Miyuki Usui, Daisuke Tatara   +5 more
doaj   +1 more source

Are bisphosphonates effective in the treatment of osteoarthritis pain? A meta-analysis and systematic review.

, 2013
Osteoarthritis (OA) is the most common form of arthritis worldwide. Pain and reduced function are the main symptoms in this prevalent disease. There are currently no treatments for OA that modify disease progression; therefore analgesic drugs and joint ...
Smith, Toby O, Nidhi Sofat (454084), Alison J. Davis (454081), Alison J Davis, Caroline B. Hing (454083), Davis, Alison J, Smith, TO, Hing, Caroline B, Sofat, N, Caroline B Hing, Davis, AJ, Nidhi Sofat, Hing, CB, Sofat, Nidhi, Toby O. Smith (454082), Toby O Smith   +15 more
core   +1 more source