Results 121 to 130 of about 693,773 (371)

Accuracy of diagnostic codes and algorithms used to identify rheumatoid arthritis and juvenile idiopathic arthritis in administrative claims and electronic health records: systematic review and meta‐analysis.

open access: yesArthritis Care &Research, Accepted Article.
Objective This systematic review aimed to assess the diagnostic accuracy of algorithms used to identify rheumatoid arthritis (RA) and juvenile idiopathic arthritis (JIA) in electronic health records (EHRs). Methods We searched MEDLINE, Embase, and CENTRAL databases and included studies that validated case definitions against a reference standard such ...
Constanza Saka‐Herrán   +10 more
wiley   +1 more source

Expression of thrombospondin-4 in the infrapatellar fat pad and synovial fluid – potential contribution to osteoarthritis pain

open access: yesArthritis Research & Therapy
Background During osteoarthritis (OA) pathogenesis, the infrapatellar fat pad (IFP) undergoes fibrotic changes that might contribute to pain development.
Sebastian Braun   +6 more
doaj   +1 more source

Bone Marrow Aspirate Concentrate-Enhanced Marrow Stimulation of Chondral Defects

open access: yesStem Cells International, 2017
Mesenchymal stem cells (MSCs) from bone marrow play a critical role in osteochondral repair. A bone marrow clot forms within the cartilage defect either as a result of marrow stimulation or during the course of the spontaneous repair of osteochondral ...
Henning Madry   +4 more
doaj   +1 more source

Biomechanical factors associated with the development of tibiofemoral knee osteoarthritis: protocol for a systematic review and meta-analysis [PDF]

open access: yes, 2016
INTRODUCTION: Altered biomechanics, increased joint loading and tissue damage, might be related in a vicious cycle within the development of knee osteoarthritis (KOA).
Dekker, Joost   +5 more
core   +4 more sources

Financial Distress and its Determinants in Rheumatoid Arthritis

open access: yesArthritis Care &Research, Accepted Article.
Objective To quantify the degree of financial distress and identify its determinants in adults with rheumatoid arthritis (RA) given the frequent chronic use of expensive disease modifying therapies. Methods We identified adults enrolled in the FORWARD databank with either RA or non‐inflammatory musculoskeletal disease (NIMSKD) completing the Functional
Amber Brown Keebler   +5 more
wiley   +1 more source

Synovial inflammation in osteoarthritis progression

open access: yesNature Reviews Rheumatology, 2022
E. Sanchez-Lopez   +4 more
semanticscholar   +1 more source

A homeostatic function of CXCR2 signalling in articular cartilage [PDF]

open access: yes, 2014
Funding This work was funded by Arthritis Research UK (grants 17859, 17971, 19654), INNOCHEM EU FP6 (grant LSHB-CT-2005-51867), MRC (MR/K013076/1) and the William Harvey Research FoundationPeer reviewedPublisher ...
Aberdeen   +17 more
core   +2 more sources

Photothermal Hydrogel with Mn3O4 Nanoparticles Alleviates Intervertebral Disc Degeneration by Scavenging ROS and Regulating Extracellular Matrix Metabolism

open access: yesAdvanced Functional Materials, EarlyView.
The MPTT‐nanozyme‐hydrogel system (Mn3O4@ChS‐HA) provides a multifunctional therapeutic strategy for intervertebral disc degeneration (IVDD), effectively targeting oxidative stress and enhancing AF repair by restoring extracellular matrix (ECM) and redox homeostasis.
Yangyang Chen   +13 more
wiley   +1 more source

Monitoring osteoarthritis: a cross-sectional survey in general practice [PDF]

open access: yes, 2013
<b>Background</b> Despite being a highly prevalent chronic condition managed predominantly in primary care and unlike other chronic conditions, osteoarthritis (OA) care is delivered on an ad hoc basis rather than through routine structured ...
Bishop, A.   +5 more
core   +6 more sources

Biomaterial Strategies for Targeted Intracellular Delivery to Phagocytes

open access: yesAdvanced Functional Materials, EarlyView.
Phagocytes are essential to a functional immune system, and their behavior defines disease outcomes. Engineered particles offer a strategic opportunity to target phagocytes, harnessing inflammatory modulation in disease. By tuning features like size, shape, and surface, these systems can modulate immune responses and improve targeted treatment for a ...
Kaitlyn E. Woodworth   +2 more
wiley   +1 more source

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