Results 161 to 170 of about 708,008 (375)

OARSI guidelines for the non-surgical management of knee, hip, and polyarticular osteoarthritis.

Osteoarthritis and Cartilage, 2019
Raveendhara R. Bannuru, M. Osani, E. Vaysbrot, Nigel K. Arden, Nigel K. Arden, K. Bennell, S. Bierma-Zeinstra, V. Kraus, L. Lohmander, J. Abbott, M. Bhandari, F. Blanco, R. Espinosa, I. Haugen, Jianhao Lin, L. Mandl, E. Moilanen, N. Nakamura, L. Snyder-Mackler, T. Trojian, Malcolm Underwood, Malcolm Underwood, T. McAlindon   +22 more
semanticscholar   +1 more source

Pharmaceutical Treatment of Osteoarthritis.

Osteoarthritis and Cartilage, 2022
M. J. Richard, J. Driban, T. McAlindon
semanticscholar   +1 more source

Single‐Cell Dissection of the Biological Function and Molecular Features Underlying the Micropeptide LSMEM1 in Kidney

Advanced Science, EarlyView.
LSMEM1, an evolutionarily conserved micropeptide with extreme hydrophobicity (aliphatic index═113) and dynamic amphiphilicity (GRAVY═0.017), features a strong α‐helical transmembrane anchor (residues 64‐86). Single‐cell analysis reveals its critical role in renal lipid homeostasis.
Peimin Liu, Hong Zhang, Shanzhi Yang, Jiaoqing Li, Danfeng Wu, Haosen Xu, Huan Jiang, Yi Jing, Guoxiang Jin, Ruobing Liu, Ning Fan, Xiaoyan Bai   +11 more
wiley   +1 more source

Constructing Dual‐Atomic Fe─Fe Sites Nanozyme for Targeted Osteoarthritis Therapy through Mitigating Oxidative Stress and Cartilage Degeneration

Advanced Science, EarlyView.
A novel bimetallic nanozyme (Fe2–NCs) with well‐defined Fe–Fe active sites is synthesized through a host–guest coordination strategy, which exhibits an exceptional therapeutic efficacy in osteoarthritis therapy. Experimental and theoretical analyses uncover the intrinsic catalytic mechanism at the atomic level, offering fundamental insights and design ...
Ting Ying, Qi Wang, Dejian Li, Yao Wang, Pengfang Zhang, Chengqing Yi, Rui Zhu   +6 more
wiley   +1 more source

Biomarkers of early stage osteoarthritis, rheumatoid arthritis and musculoskeletal health [PDF]

, 2015
Usman Ahmed, Attia Anwar, Richard S. Savage, Matthew L. Costa, Nicola D. Mackay, Andrew Filer, Karim Raza, Richard A. Watts, Paul G. Winyard, Joanna M. Tarr, Richard Haigh, Paul J. Thornalley, Naila Rabbani   +12 more
openalex   +1 more source

Clustering of comorbidities and associated outcomes in people with osteoarthritis - A UK Clinical Practice Research Datalink study

, 2022
Subhashisa Swain, Carol Coupland, Vicky Y. Strauss, Christian Mallen, C F Kuo, Aliya Sarmanova, S. Bierma-Zeinstra, Martin Englund, Daniel Prieto‐Alhambra, Michael Doherty, Weiya Zhang   +10 more
openalex   +2 more sources

Exhausting circ_0136474 and Restoring miR-766-3p Attenuate Chondrocyte Oxidative Injury in IL-1β-Induced Osteoarthritis Progression Through Regulating DNMT3A [PDF]

, 2021
Haiquan Zhu, Shaobo Zhu, Xiuchao Shang, Xiangsheng Meng, Sheng Jing, Li Yu, Yu Deng   +6 more
openalex   +1 more source

Epidemiology of Osteoarthritis.

Osteoarthritis and Cartilage, 2021
Kelli D. Allen, L. Thoma, Y. Golightly
semanticscholar   +1 more source

Osteoarthritis [PDF]

Acta Orthopaedica Scandinavica, 1998
openaire   +2 more sources

Targeted Inhibition of CD74+ Macrophages by Luteolin via CEBPB/P65 Signaling Ameliorates Osteoarthritis Progression

Advanced Science, EarlyView.
This study identifies CD74⁺ macrophages as key drivers of synovial inflammation in osteoarthritis (OA). The flavonoid luteolin is predicted to inhibit this pathway by blocking Nuclear Factor Kappa‐light‐chain‐enhancer of Activated B cells (NF‐κB) signaling. To enhance delivery, a targeted nanoplatform (MDSPL) is developed.
Rui Peng, Bo Yu, Lei Zhang, Zhaowen Xue, Lutian Yao, Qingjun Yang, Zitao Liu, Sizhi Wu, Yongquan Huang, Xiaofei Zheng, Huiying Guo, Songwei Huan, Tao Jiang, Huajun Wang, Yulong Wei, Tao Gui   +15 more
wiley   +1 more source