Mechanisms of Osteoarthritis (OA) Pain. [PDF]
Curr Osteoporos Rep, 2018 Osteoarthritis (OA) is a major cause of pain and disability worldwide. There is, however, a relatively poor correlation between the severity of OA based on plain radiograph changes and symptoms. In this review, we consider the mechanisms of pain in OA.It is now widely recognised that OA is a disease of the whole joint.
O'Neill TW, Felson DT.
europepmc +5 more sources
eLife, 2022 Background: Metabolic syndrome–associated osteoarthritis (MetS-OA) is a distinct osteoarthritis phenotype defined by the coexistence of MetS or its individual components. Despite the high prevalence of MetS-OA, its pathogenic mechanisms are unclear.
Weiping Su +11 more
doaj +1 more source
β-Hydroxybutyrate alleviates cartilage senescence through hnRNP A1-mediated up-regulation of PTEN
Experimental Gerontology, 2023 Senescence chondrocytes play an important role in Osteoarthritis (OA) progression. However, alleviating OA progression through senescent chondrocyte intervention still faces great challenges.
Guang Xia +8 more
doaj +1 more source
Are bisphosphonates effective in the treatment of osteoarthritis pain? A meta-analysis and systematic review. [PDF]
, 2013 Osteoarthritis (OA) is the most common form of arthritis worldwide. Pain and reduced function are the main symptoms in this prevalent disease. There are currently no treatments for OA that modify disease progression; therefore analgesic drugs and joint ...
AD Beswick +37 more
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Increasing the capacity of health cadres to prevent and self-management of Osteoarthritis
Abdimas: Jurnal Pengabdian Masyarakat Universitas Merdeka Malang, 2023 Osteoarthritis (OA) is a clinical syndrome characterized by joint pain with varying degrees of functional limitations that impact quality of life. Data in Indonesia shows that the national prevalence of osteoarthritis is 7.3%. Several factors in the high
Arifin Triyanto +3 more
doaj +1 more source
Profile of Patients’ Osteoarthritis at Tertiary and Teaching in Aceh, Indonesia
Surabaya Physical Medicine and Rehabilitation Journal, 2023 Background: Osteoarthritis is a degenerative joint disease characterized by damage of cartilage in the joints and subchondral bones that cause pain in a joint.
Alex Kurniawan Gan +3 more
doaj +1 more source
Epigenetic Regulation in Knee Osteoarthritis
Frontiers in Genetics, 2022 Osteoarthritis (OA) is a complicated disease with both hereditary and environmental causes. Despite an increase in reports of possible OA risk loci, it has become clear that genetics is not the sole cause of osteoarthritis.
Zhengyu Cai +4 more
doaj +1 more source
Journal of Education, Health and Sport, 2023 Introduction and aim of the study: Osteoarthritis (OA) and depression are leading causes of disease burden worldwide and important public health problems.
Ignacy Tołwiński +12 more
doaj +1 more source
Sexually dimorphic tibia shape is linked to natural osteoarthritis in STR/Ort mice [PDF]
, 2018 Human osteoarthritis (OA) is detected only at late stages. Male STR/Ort mice develop knee OA spontaneously with known longitudinal trajectory, offering scope to identify OA predisposing factors.
A.A. Pitsillides +57 more
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The Validity, Reliability, Measurement Error, and Minimum Detectable Change of the 30‐Second Fast‐Paced Walk Test in Persons with Knee Osteoarthritis: A Novel Test of Short‐Distance Walking Ability [PDF]
, 2019 Objective To develop and establish the reliability, validity, measurement error, and minimum detectable change of a novel 30‐second fast‐paced walk test (30SFW) in persons with knee osteoarthritis (OA) that is easy to administer and can quantify walking ...
Folkins, DPT, Erik +3 more
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