Results 31 to 40 of about 126,184 (308)

Quantitative sensory testing in painful hand osteoarthritis demonstrates features of peripheral sensitisation. [PDF]

, 2012
Hand osteoarthritis (HOA) is a prevalent condition for which treatments are based on analgesia and physical therapies. Our primary objective was to evaluate pain perception in participants with HOA by assessing the characteristics of nodal involvement ...
Ejindu, V, Hermansson, M, Heron, C, Kiely, P, Sofat, N, Wajed, J   +5 more
core   +2 more sources

MATN3 Gene Polymorphism Is Associated with Osteoarthritis in Chinese Han Population: A Community-Based Case-Control Study

The Scientific World Journal, 2012
Background. The matrilin, especially matrilin-3 (MATN3), are reported to play important roles in the pathophysiology of osteoarthritis (OA). To explore the relationship between MATN3 SNP6 (rs8176070) and primary OA, we conducted a community-based case ...
Jiaao Gu, Jiesheng Rong, Fulin Guan, Liying Jiang, Shuqing Tao, Guofa Guan, Tianzun Tao   +6 more
doaj   +1 more source

"Let's talk about OA pain": a qualitative analysis of the perceptions of people suffering from OA. Towards the development of a specific pain OA-Related questionnaire, the Osteoarthritis Symptom Inventory Scale (OASIS). [PDF]

PLoS ONE, 2013
INTRODUCTION:Pain is the primary outcome measurement in osteoarthritis, and its assessment is mostly based on its intensity. The management of this difficult chronic condition could be improved by using pain descriptors to improve analyses of painful ...
Christine Cedraschi, Sylvie Delézay, Marc Marty, Francis Berenbaum, Didier Bouhassira, Yves Henrotin, Françoise Laroche, Serge Perrot   +7 more
doaj   +1 more source

The Puzzle of Generalized Osteoarthritis (OA) — Is OA a Systemic Enthesopathy? [PDF]

The Journal of Rheumatology, 2012
Osteoarthritis (OA) is a common condition that has a major influence on patients’ health-related quality of life. Unfortunately, the riddle concerning the pathogenesis of the disease is still not solved. Generally, we believe that OA is a failure of the whole joint caused by a combination of systemic risk factors and local biomechanical factors1,2 ...
openaire   +2 more sources

TSG-6 – a double-edged sword for osteoarthritis (OA) [PDF]

Osteoarthritis and Cartilage, 2018
To explore mechanisms underlying the association of TSG-6 with osteoarthritis (OA) progression.TSG-6-mediated heavy chain (HC) transfer (TSG-6 activity) and its association with inflammatory mediators were quantified in knee OA (n=25) synovial fluids (SFs).
C.-H. Chou, D.E. Attarian, H.-G. Wisniewski, P.A. Band, V.B. Kraus   +4 more
openaire   +2 more sources

Perceptions towards aqua-based exercise among older adults with osteoarthritis who have discontinued participation in this exercise mode [PDF]

, 2016
Aim: This study aimed to investigate reasons for ceasing participation in aqua-based exercise among older adults with osteoarthritis (OA). Methods: Eleven adults over 60 years of age with OA participated in one of two focus groups, during which they ...
Alpass, Benbow, Borman, Bunning, Der Ananian, Der Ananian, Fisken, Fontaine, Gulick, Henwood, Hootman, Kitzinger, Krueger, Lees, Lin, Litt, Loeb, Marks, McAlindon, Melillo, Newson, Petursdottir, Schutzer, Tak, Thomas, Watkins, Westby, Wilcox   +27 more
core   +1 more source

Targeting Some Key Metalloproteinases by Nano-Naringenin and Amphora coffeaeformis as a Novel Strategy for Treatment of Osteoarthritis in Rats

Pharmaceuticals, 2023
Osteoarthritis (OA) represents the highest degenerative disorder. Because cartilage erosion is a common pathological alteration in OA, targeting some key metalloproteinases such as MMP-3, ADAMTS-5 besides their inhibitor TIMP-3 by natural products, could
Nema S. Shaban, Abeer M. Radi, Mohamed A. Abdelgawad, Mohammed M. Ghoneim, Rasha Hamed Al-Serwi, Randa M. Hassan, Eman T. Mohammed, Rania A. Radi, Fatma M. Halfaya   +8 more
doaj   +1 more source

Serum microRNA array analysis identifies miR-140-3p, miR-33b-3p and miR-671-3p as potential osteoarthritis biomarkers involved in metabolic processes. [PDF]

, 2017
Background: MicroRNAs (miRNAs) in circulation have emerged as promising biomarkers. In this study, we aimed to identify a circulating miRNA signature for osteoarthritis (OA) patients and in combination with bioinformatics analysis to evaluate the utility
A Brazma, A Nan, A Okuhara, A Turchinovich, B Aryal, B Mayr, B Sharif, B Zhang, BM Bolstad, BM Kuhn, BM Mayr, C Beyer, C Chen, C Guay, C Taurino, CL Andersen, D Dlouha, D Iliopoulos, D Zhang, DT Felson, F Kostopoulou, FE Nicolas, G Dennis Jr, G Li, G Tardif, GD Miles, GR Sondag, GS Lien, H Causton, JB van Meurs, JD Storey, JD Storey, KC Vickers, L Qi, M Cross, M Parrizas, MB Goldring, MC Hochberg, MD Paraskevopoulou, MP Gantier, OF Laterza, Q Zhuo, R Gernapudi, RF Loeser, RI Gregory, S Kluzek, S Kumar, S Miyaki, T Thomou, TA Karlsen, VM Borgonio Cuadra, W Cleveland, WM Reichmann, X Chen, X Chen, X Tan, X Wang, Y Klipper-Aurbach, Y Zhang, YH Li   +59 more
core   +2 more sources

Causal association of genetically determined plasma metabolites with osteoarthritis: a two-sample Mendelian randomization study

Frontiers in Medicine
BackgroundWe aimed to elucidate the causal relationship between plasma metabolites and the vulnerability to Osteoarthritis (OA), encompassing both hip OA and knee OA.MethodsWe conducted a two-way two-sample Mendelian randomization (MR) analysis to ...
Qingsong Fu, Xinhua Yuan, Weibin Wang, Xinyou Han, Jiakai Zhang, Junlong Wu, Yao Wang   +6 more
doaj   +1 more source

Cross-sectional study on the relationship between Body Mass Index and severity of knee osteoarthritis [PDF]

Romanian Journal of Rheumatology
Background. Musculoskeletal diseases like osteoarthritis (OA) are widespread. OA affects the knees, makes the joints wear out and hurt, and makes it hard to move around.
Mohd. Shifa Hasan, Aditya Kumar Mishra, Mohd. Bilal Kaleem, Vikash Thaledi   +3 more
doaj   +1 more source