Results 131 to 140 of about 126,184 (308)

Association of obesity and knee osteoarthritis [PDF]

Journal of Sharif Medical & Dental College, 2017
Objective: To determine the association between obesity and severity of knee osteoarthritis. Methodology: It was a cross-sectional descriptive study conducted in the Department of Orthopaedics Surgery, Sharif Medical City Hospital, Lahore.
Farooq Azam Khan, Ahmad Rasool, Hajra Tariq, Abbas Bajwa   +3 more
doaj  

Physical Activity Minimum Threshold Predicting Improved Function in Adults With Lower‐Extremity Symptoms [PDF]

, 2017
Objective To identify an evidence‐based minimum physical activity threshold to predict improved or sustained high function for adults with lower‐extremity joint symptoms.
Ainsworth, Barbara, Chang, Rowland W., Dunlop, Dorothy D., Ehrlich-Jones, Linda S., Gilbert, Abigail L., Lee, Jungwha, Pellegrini, Christine A., Pinto, Daniel, Semanik, Pamela A., Song, Jing   +9 more
core   +1 more source

Anti‐Carbamylated Protein Antibodies Stabilize Carbamylated Histone H3 to Promote Synovial Activation and Neutrophil Extracellular Trap‐Mediated Bone Loss in Rheumatoid Arthritis

Arthritis &Rheumatology, EarlyView.
Objective Carbamylation, a nonenzymatic post‐translational modification, contributes to rheumatoid arthritis (RA) pathogenesis. Anti‐carbamylated protein antibodies (anti‐CarP) occur in around 50% of patients with RA and associate with greater joint damage. Neutrophil extracellular traps (NETs) are a major source of carbamylated autoantigens. We sought
Shuichiro Nakabo, Norio Hanata, Eduardo Patino‐Martinez, Ronald Holewinski, Ana Barrera‐Vargas, Javier Merayo‐Chalico, Scott A. Coonrod, David A. Fox, Mariana J. Kaplan, Carmelo Carmona‐Rivera   +9 more
wiley   +1 more source

Nerve growth factor is sufficient to cause multiple osteoarthritis‐relevant pathological features in naïve murine knee joints

Arthritis &Rheumatology, Accepted Article.
Objective Nerve growth factor (NGF), a key mediator of pain, is increased in osteoarthritic (OA) joints. Antibodies against NGF show analgesic effects in painful knee OA, but clinical development was stopped due to side‐effects in the joints. Knowledge about the biological effects of NGF on joint tissues is limited.
Alia M. Obeidat, Michael D. Newton, Jun Li, Baofeng Hu, Shingo Ishihara, Lindsey Lammlin, Lucas M. Junginger, Easton C. Farrell, Lai Wang, Frank C. Ko, Richard J. Miller, Carla R. Scanzello, Tristan Maerz, Rachel E. Miller, Anne‐Marie Malfait   +14 more
wiley   +1 more source

An Investigator-Initiated, Prospective, Single-Center, Open-Label Clinical Study to Evaluate Safety and Performance of Intra-Articular Hyaluronic Acid (IA-HA) (Biovisc Ortho) in Patients with Osteoarthritis (OA) of the Knee. [PDF]

Clin Pharmacol, 2021
Gupta A, Channaveera C, Anand V, Sethi S.   +3 more
europepmc   +1 more source

Osteoarthritis, entheses, and long bone cross-sectional geometry in the Andes: Usage, history, and future directions. [PDF]

, 2019
Akin to approaches encouraged by Verano (1997) in the Andes, and Ortner (2011, 2012) for general paleopathological studies, this article focuses on accurate descriptions and definitions of osteoarthritis, entheses, and long bone cross-sectional geometry.
Becker, Sara K
core   +1 more source

Behavioral Incentives for Exercise and Intra‐Articular Glucocorticoids for Knee Osteoarthritis: Results From a Factorially Designed Pragmatic Randomized Clinical Trial

Arthritis &Rheumatology, EarlyView.
Objective The purpose of this study was to determine the benefit of a behaviorally designed incentive program and glucocorticoid injections in reducing symptoms and promoting physical activity in patients with knee osteoarthritis (KOA). Methods This was a pragmatic, multisite, factorially designed, blinded, randomized clinical trial.
Joshua F. Baker, Katherine D. Wysham, Mercedes Quinones, Bryant R. England, Kaitian Jin, Marianna Olave, Sarah Wetzel, Rachel L. Gillcrist, Criswell Lavery, Natalie Keller, Bridget Kramer, Bibianna Ateh, Hannah Brubeck, Daniel K. White, Alexis Ogdie, Rui Xiao, Tuhina Neogi, Carla R. Scanzello   +17 more
wiley   +1 more source

Autoantibodies to Joint‐Related Peptides Are Associated with Onset of Rheumatoid Arthritis in Presymptomatic Seronegative Individuals

Arthritis &Rheumatology, Accepted Article.
Objective To identify autoantibodies in presymptomatic individuals that associate with the onset of rheumatoid arthritis (RA), and to distinguish early RA from osteoarthritis (OA), particularly in individuals lacking classic RA serological markers. Methods We analyzed serum and plasma from three cohorts: pre‐symptomatic individuals who later developed ...
Outi Sareila, Linda Johansson, Anders Lundquist, Monica Leu Agelii, Lei Cheng, Yibo He, Erik Lönnblom, Maria Andersson, Jan Kihlberg, Anders Esberg, Inger Gjertsson, Rikard Holmdahl, Solbritt Rantapää‐Dahlqvist   +12 more
wiley   +1 more source

Combined Medial Unicompartmental Knee Arthroplasty and Revision Allograft Anterior Cruciate Ligament Reconstruction

Arthroscopy Techniques, EarlyView.
Abstract Combined medial unicompartmental knee arthroplasty and revision anterior cruciate ligament reconstruction with an Achilles tendon allograft offers a promising solution for young, active patients with isolated medial compartment osteoarthritis and a failed prior anterior cruciate ligament reconstruction.
Ryan J. Froom, Alexi J. Panos, Molly E. Kessenich, Nate Dickinson, Mikalyn T. DeFoor, Nathan Cafferky, Matthew T. Provencher   +6 more
wiley   +1 more source

Intramuscular fat infiltration: a hidden covariate in the sarcopenia–knee osteoarthritis association? Leveraging Osteoarthritis Initiative magnetic resonance imaging data for adjustment: comment on the article by Wu et al

Arthritis &Rheumatology, EarlyView.
Huihui Wu, Zhi Wang, Liang Guo
wiley   +1 more source