Vitamin D: Physiology, Pharmacology and Clinical Evidence for Supplementation—A Narrative Review
ABSTRACT Vitamin D is a nutrient and prohormone obtained from diet and supplements and synthesized in the skin. It is essential for calcium and phosphate homeostasis and skeletal health and influences multiple extra‐skeletal processes, yet deficiency remains common worldwide.
Jyrki K. Virtanen
wiley +1 more source
Biochemical Evaluation of Bone Health in Children with Phenylketonuria, Organic Acidemias, and Glycogen Storage Diseases Under Dietary Management. [PDF]
Gokalp S, Pasaoglu H.
europepmc +1 more source
ABSTRACT Porous scaffolds based on pure poly(ε‐caprolactone) (PCL) and on biocomposite made of PCL and feather‐extracted β‐keratin (FK) were fabricated by salt‐leaching method. FK was incorporated into PCL to address the limited bioactivity and hydrophobic nature of PCL, with the aim of improving cell–material interactions for bone tissue engineering ...
Gianluca Rinaldi +6 more
wiley +1 more source
Analysis of Osteocalcin Hormone Proteoforms with Vitamin D Deficiency in Patients with Diabetes Mellitus Using Multiple-Reaction Monitoring-Mass Spectrometric Immunoassay Approach. [PDF]
Nimer RM +6 more
europepmc +1 more source
This study unravels that bone fracture accelerates diabetic wound healing by releasing exosomal microRNA (miR‐130b‐3p). To mimic this bone‐skin crosstalk, we engineered a self‐assembling agomir‐130b‐3p nanocomplex. Delivered via a photocrosslinkable hydrogel, this bio‐inspired therapy provides sustained localized agomir release.
Tao Shen +14 more
wiley +1 more source
Polyphenol‐rich plant extracts provide natural immunomodulatory protection for oral health through complementary antioxidant, antibacterial, and anti‐inflammatory actions. Their potential to reduce harmful microbial activity and inflammation highlights the promise of dietary polyphenols as a natural strategy for maintaining oral health and preventing ...
Deepa Subramanian +3 more
wiley +1 more source
LP533401 treatment alters vitamin K metabolism, bone Gla-OC/Glu-OC ratios, and improves mineral status of the skeleton in rats with chronic kidney disease. [PDF]
Kopańko M +6 more
europepmc +1 more source
The Role of Ferroptosis Induced by Iron Overload in Osteoblast and Osteoclast Function
ABSTRACT Iron overload disrupts bone homeostasis by suppressing osteoblast survival and mineralization, while promoting osteoclastogenesis. As a programmed cell death driven by iron‐dependent lipid peroxidation and glutathione peroxidase 4 (GPX4) downregulation. This study investigated the role of ferroptosis in bone cells under iron overload. Exposure
Supagarn Sooksawanwit +9 more
wiley +1 more source
Effects of Synbiotic Supplementation on Bone Turnover Markers in Kidney Transplant Recipients: A Randomized Controlled Trial. [PDF]
Karimi Z +5 more
europepmc +1 more source

