Abstract Bed rest accelerates bone loss and may exacerbate skeletal fragility. This study examined the effects of 14 days of head‐down tilt bed rest (HDBR) with or without exercise, and subsequent recovery, on bone turnover, density and structure in older adults. Twenty‐two healthy older adults (55–65 years) completed the HDBR protocol.
Guy Hajj‐Boutros +11 more
wiley +1 more source
Protein and Peptide Inhibitors of Mineralization: A Systematic Review of In Vitro Studies
In vitro evidence from crystallization assays demonstrates that peptides inhibit mineral nucleation and crystal growth through sequence‐dependent interactions (acidic residues and phosphorylation) with mineral surfaces. In cell cultures, these molecules reduce calcium deposition and ALP activity and modulate the expression of biomineralization‐related ...
Alberto Mimila‐Cortes +7 more
wiley +1 more source
Osteocalcin and Human Milk [PDF]
W B, Pittard, K M, Geddis, B W, Hollis
openaire +2 more sources
Stage-dependent analysis of IL-6, TGF-β, osteocalcin, and sRANKL in the synovial fluid of dogs with osteoarthritis. [PDF]
Neumann S, Diekmann H, Lauenstein S.
europepmc +1 more source
Molecular Basis and Clinical Spectrum of WNT10A‐Related Oligodontia
Cellular Mechanism behind WNT10A phenotypes. ABSTRACT WNT10A mutations, a major genetic determinant of dental agenesis and ectodermal dysplasia, exert profound effects on craniofacial development. Although classified as rare disorders, these mutations account for more than half of oligodontia cases, reflecting their critical role.
Perennes Elise +5 more
wiley +1 more source
Circulating Total Osteocalcin Reflects Bone Mineral Physiology Rather than Metabolic Risk in Pediatric Obesity. [PDF]
Nowicki JK +3 more
europepmc +1 more source
Racemisation of Amino Acids: From Synthetic Challenge to Biological Significance
Racemisation, once considered an undesirable synthetic side reaction, also occurs naturally in amino acids and influences biological processes. Evidence links stereochemical conversion to ageing, protein turnover, and cellular development. This review examines mechanisms, control strategies in synthesis, applications and implications in physiology ...
Othman Al Musaimi
wiley +1 more source
Rapid improvement in glycaemic control is associated with increased circulating osteocalcin in type 2 diabetes: a concise observational comparative study. [PDF]
Dardari D +5 more
europepmc +1 more source
Osteocalcin- and Osteopontin-Containing Neurons in the Rat Hind Brain
Toshihiko Suzuki +2 more
openalex +2 more sources
An Investigation Into the Role of Osteocalcin in Human Arterial Smooth Muscle Cell Calcification
Sophie Millar +5 more
openalex +1 more source

