Results 61 to 70 of about 11,146 (233)

Musculoskeletal Diseases: Mechanisms and Therapeutic Advances

MedComm, Volume 6, Issue 12, December 2025.
Musculoskeletal diseases comprise a broad spectrum of inflammatory, degenerative, and neoplastic disorders. Increasing evidence highlights the central role of immune regulation in their pathogenesis, with complex interactions among immune, bone, muscle, and stromal cells.
Xiao Ma, Eloy Yinwang, Xupeng Chai, Fangqian Wang, Zehao Chen, Shengdong Wang, Hao Zhou, Yucheng Xue, Jiangchu Lei, Fanglu Chen, Hengyuan Li, Shixin Chen, Shenzhi Zhao, Kelei Wang, Liang Chen, Junjie Gao, Zhaoming Ye, Nong Lin   +17 more
wiley   +1 more source

Approach to the management of solitary osteochondroma of the body of the pubis

Journal of Orthopaedic Diseases and Traumatology, 2019
Osteochondroma is considered the most common benign tumor of the bone (20%–50% of all benign tumors); some consider them arising from small cartilaginous nodules present in the periosteum. They are developmental malformation or true neoplasm.
Rajnand Kumar, Saurabh Kumar, Tarun Vijay, Deepankar Verma   +3 more
doaj   +1 more source

Incorporating Clinical Examination Skills Into a Preclinical Anatomy Course: A Method for Facilitating Engagement and Interest

Clinical Anatomy, Volume 38, Issue 7, Page 791-795, October 2025.
ABSTRACT Anatomy instruction is enhanced when students are engaged and interested in course material, and the relevance of the subject matter to their academic success and professional careers is emphasized. We developed a learning activity for a pre‐clinical anatomy course using the clinical skills of inspection and palpation of a cadaver donor to ...
Aysha Alani, Justin O'Leary, Andrew Stieb, John P. McNamara, Michael F. Nolan   +4 more
wiley   +1 more source

A rare case of pediatric osteochondroma presenting as hemothorax

Journal of Indian Association of Pediatric Surgeons, 2020
Isolated osteochondroma presenting as hemothorax is a rare entity. A 7-year-old boy presented with respiratory distress and diagnosed with hemothorax, and computed tomography showed osteochondroma and removal with resection of the rib was curative.
Pavai Arunachalam, Cenita J Sam, K Jothi Lakshmi, Hari Baskar Shanmugham   +3 more
doaj   +1 more source

An Integrative Genotyping and Gene Expression Profiling of the Mutated Human FAM111B Gene and Fibrosis‐Associated Pathway in the POIKTMP Syndrome

Journal of Cellular and Molecular Medicine, Volume 29, Issue 19, October 2025.
ABSTRACT Poikiloderma with tendon contracture, myopathy and pulmonary fibrosis (POIKTMP) is a rare hereditary disorder caused by mutations in the FAM111B gene, characterised by multi‐organ fibrosis, particularly affecting the lungs. This study investigates the molecular mechanisms of fibrosis in POIKTMP through genotyping and gene expression profiling ...
Nadine Tambwe, Musalula Sinkala, Oluwafemi G. Oluwole, Nonhlanhla P. Khumalo, Afolake Arowolo   +4 more
wiley   +1 more source

Displasia Epifisaria Hemimélica en rótula: (descripción de un nuevo caso y revisión bibliográfica) [PDF]

, 1990
Se describe un nuevo caso de Displasia Epifisaria Hemimélica que asienta en una legalización muy poco frecuente cual es la rótula. Realizan una amplia revisión bibliográfica de la literatura mundial y se comentan las variaciones observadas en cuanto al ...
Acosta González, F., Alvarez de Cienfuegos, M.C., Hernández Hernández, M. A., López Moratalla, G., López Moratalla, M., Villen Jaldo, A.   +5 more
core  

The residual STL volume as a metric to evaluate accuracy and reproducibility of anatomic models for 3D printing: application in the validation of 3D-printable models of maxillofacial bone from reduced radiation dose CT images. [PDF]

, 2015
BackgroundThe effects of reduced radiation dose CT for the generation of maxillofacial bone STL models for 3D printing is currently unknown. Images of two full-face transplantation patients scanned with non-contrast 320-detector row CT were reconstructed
Cai, Tianrun, Demehri, Shadpour, Giannopoulos, Andreas A, Kumamaru, Kanako K, Liacouras, Peter, Mitsouras, Dimitris, Rybicki, Frank J, Schultz, Kurt, Shu Small, Kirstin M   +8 more
core   +1 more source

The Pathophysiological Functions of Heparanases: From Evolution, Structural and Tissue‐Specific Perspectives

The FASEB Journal, Volume 39, Issue 17, 15 September 2025.
Heparanase 1 (HPSE1) and Heparanase 2 (HPSE2) exhibit opposing expression patterns and functions in pathological contexts, such as cancer. Here, we describe their specific expression in immune cells and their implications in skin diseases. Although they are structurally similar and considered to be ‘cousins’, we found no common ancestor and that HPSE2 ...
Elham Vahdatahar, Clément Daviaud, Hugo Main, Rachel Havret, Claire Debarnot, Laure Favot‐Laforge, Jean‐François Jégou, Ingrid Fruitier‐Arnaudin, Antoine Dufour, Romain Vivès, Franck Morel, Yves Bourne, Kévin Baranger   +12 more
wiley   +1 more source

Teleangiectatic Osteosarcoma Treated by Surgery and Chemotherapy: A Report of 223 Affected Patients From the Cooperative Osteosarcoma Study Group (COSS)

Cancer Medicine, Volume 14, Issue 17, September 2025.
ABSTRACT Purpose Teleangiectatic osteosarcoma is a histologic subtype of osteosarcoma that can mimic aneurysmal bone cysts and has so far been incompletely characterized. Patients and Methods We used the database of the Cooperative Osteosarcoma Study Group COSS (patient‐registration 1980–2019) to better understand this rare histologic variant.
Stefan S. Bielack, Vanessa Mettmann, Daniel Baumhoer, Andreas Beilken, Claudia Blattmann, Godehard Friedel, Jendrik Hardes, Wolf Hassenpflug, Leo Kager, Matthias Kevric, Thekla von Kalle, Andreas Kulozik, Markus Metzler, Michaela Nathrath, Claudia Rossig, Benjamin Sorg, Mathias Werner, Stefanie Hecker‐Nolting   +17 more
wiley   +1 more source

Exóstosis cartilaginosas múltiples como causa de compresión medular en un husky de 6 meses [PDF]

, 2003
Se describe un raro caso de Exóstosis Cartilaginosas Múltiples en una localización poco frecuente como es la lámina dorsal vertebral, produciendo una mielopatía comprensiva. La paresia posterior progresiva resultante fue tratada con éxito quirúrgicamente
Casais, R., Chico, A., Martínez, J., Sánchez, C.   +3 more
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