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Evidence for osteocyte regulation of bone homeostasis through RANKL expression
Nature Medicine, 2011Kosaku Kurata +2 more
exaly +2 more sources
Zeitschrift fur Orthopadie und Unfallchirurgie, 2019
For a long time, osteocytes were regarded as passive bystanders of bone metabolism. Bone remodeling was considered to be an interplay between bone forming osteoblasts and bone degrading osteoclasts. However, the dogma of osteocytes as bystanders within the bone has changed fundamentally since the turn of the millenium.
Markus, Rupp +5 more
openaire +2 more sources
For a long time, osteocytes were regarded as passive bystanders of bone metabolism. Bone remodeling was considered to be an interplay between bone forming osteoblasts and bone degrading osteoclasts. However, the dogma of osteocytes as bystanders within the bone has changed fundamentally since the turn of the millenium.
Markus, Rupp +5 more
openaire +2 more sources
Current Osteoporosis Reports, 2021
While the function of osteocytes under physiologic conditions is well defined, their role and involvement in cancer disease remains relatively unexplored, especially in a context of non-bone metastatic cancer. This review will focus on describing the more advanced knowledge regarding the interactions between osteocytes and cancer.We will discuss the ...
Fabrizio Pin +3 more
openaire +2 more sources
While the function of osteocytes under physiologic conditions is well defined, their role and involvement in cancer disease remains relatively unexplored, especially in a context of non-bone metastatic cancer. This review will focus on describing the more advanced knowledge regarding the interactions between osteocytes and cancer.We will discuss the ...
Fabrizio Pin +3 more
openaire +2 more sources
The International Journal of Biochemistry & Cell Biology, 2004
Osteocytes are the most numerous cells in mature bone and have the potential to live as long as the organism itself. However, study and subsequent understanding of osteocyte biology has been thwarted by the remote location of the cell in the mineralized matrix.
Melissa L, Knothe Tate +3 more
openaire +2 more sources
Osteocytes are the most numerous cells in mature bone and have the potential to live as long as the organism itself. However, study and subsequent understanding of osteocyte biology has been thwarted by the remote location of the cell in the mineralized matrix.
Melissa L, Knothe Tate +3 more
openaire +2 more sources
Bone, 2021
MicroRNAs, identified in the early 1990s, are believed to regulate approximately 30% of the human genome. The role of microRNA in bone cells was first reported in 2007 in a manuscript showing that microRNA-223 is essential for osteoclast differentiation in vitro, and a few studies reported a role of microRNAs in osteoblasts the same year.
Plotkin, Lilian I., Wallace, Joseph M.
openaire +3 more sources
MicroRNAs, identified in the early 1990s, are believed to regulate approximately 30% of the human genome. The role of microRNA in bone cells was first reported in 2007 in a manuscript showing that microRNA-223 is essential for osteoclast differentiation in vitro, and a few studies reported a role of microRNAs in osteoblasts the same year.
Plotkin, Lilian I., Wallace, Joseph M.
openaire +3 more sources
Biofabrication, 2020
Biofabrication of personalized titanium scaffold mimicking that of the osteocyte microenvironment is challenging due to its complex geometrical cues. The effect of scaffolds geometrical cues and implantation sites on osteogenesis is still not clear.
Xuan Pei +12 more
semanticscholar +1 more source
Biofabrication of personalized titanium scaffold mimicking that of the osteocyte microenvironment is challenging due to its complex geometrical cues. The effect of scaffolds geometrical cues and implantation sites on osteogenesis is still not clear.
Xuan Pei +12 more
semanticscholar +1 more source

