Results 71 to 80 of about 15,376 (162)

Femoral nonunion with segmental bone defect treated by distraction osteogenesis with monolateral external fixation

Journal of Orthopaedic Surgery and Research, 2017
Background Currently, the common treatment for femoral nonunion with large segmental bone defect is difficult and complex. The effective surgical methods are rare, include vascularized bone grafting, Masquelet technique and Ilizarov distraction ...
Qun Zhang, Wei Zhang, Zhuo Zhang, Licheng Zhang, Hua Chen, Ming Hao, Junhao Deng, Peifu Tang   +7 more
doaj   +1 more source

Auditory Outcomes in Patients Undergoing Orthognathic Surgery: An Analysis of Middle Ear Disease

Otolaryngology–Head and Neck Surgery, Volume 173, Issue 6, Page 1463-1469, December 2025.
Abstract Objective To characterize postoperative Eustachian tube dysfunction (ETD) and middle ear pathology following Le Fort I osteotomy. Study Design Retrospective cohort study. Setting Single tertiary care center. Methods Patients who underwent Le Fort I (LF1) osteotomy between 2000 and 2022 were identified using CPT codes.
Sarah E. Hughes, Shadi Mehrabi, Grace Carvette, Anahita H. Mehta, Emily Z. Stucken   +4 more
wiley   +1 more source

Comparative analysis of dental implant treatment outcomes following mandibular reconstruction with double‐barrel fibula bone grafting or vertical distraction osteogenesis fibula: a retrospective study [PDF]

, 2015
PurposeThe purpose of this study was twofold: (i) to compare vertical bone height (VBH) after tumor resection through grafting with either a double‐barrel fibula (DBF) technique or vertical distraction osteogenesis of the fibula (VDOF); (ii) to compare ...
Huang, Wei, Kaigler, Darnell, Sun, Jian, Wang, Feng, Wu, Yiqun, Zhang, Chenping   +5 more
core   +1 more source

Treatment of severe micrognathia in an adult with distraction osteogenesis: A case report

Clinical Case Reports, 2023
Key Clinical Message Distraction osteogenesis (DO) of the mandible is often performed at a young age, and there are few reports after age 30, as in this case.
Katsuhisa Sekido, Kumiko Fujiwara, Hidetake Tachinami, Shuichi Imaue, Keishi Hanashiro, Makoto Noguchi   +5 more
doaj   +1 more source

The Sirt1‐Piezo1 Axis Promotes Bone Formation and Repair in Mice

Advanced Science, Volume 12, Issue 44, November 27, 2025.
Piezo1 upregulates in cartilage callus during bone repair, where its deletion impairs ossification and healing in mice, while activation enhances these processes. Sirt1 positively regulates Piezo1 expression and activity to promote osteogenesis and bone repair in mice.
Donghao Gan, Yi Ran, Hong Pan, Qinnan Yan, Wenjing Zhang, Bo Zhou, Pengzhi Xu, Rongdong Liao, Haipeng Xue, Will Jiang, Tailin He, Qingyun Jia, Lei Qin, Francis Y Lee, Di Chen, Chuanju Liu, Guozhi Xiao   +16 more
wiley   +1 more source

Advances in Magnesium Metal and Its Alloys for Promoting Angiogenesis

Journal of Biomedical Materials Research Part B: Applied Biomaterials, Volume 113, Issue 11, November 2025.
ABSTRACT Magnesium‐based materials show great promise for bone repair due to their biodegradability, bone‐like mechanical properties, and dual pro‐angiogenic/osteogenic activities. Pure magnesium implants enhance vascularization in bone defect models through Mg2+ release.
Junjie Huang, Jialong Wu, Di Liu, Peng Gao   +3 more
wiley   +1 more source

Bone growth following demineralized bone matrix implantation requires angiogenesis [PDF]

, 2016
Angiogenesis is required for endochondral ossification during development and fracture healing; however the exact mechanisms and temporal relationship between the two processes remains unclear.
Lam, Stephanie
core  

VEGF with AMD3100 Endogenously Mobilizes Mesenchymal Stem Cells and Improves Fracture Healing [PDF]

, 2018
A significant number of fractures develop non‐union. Mesenchymal stem cell (MSC) therapy may be beneficial, however, this requires cell acquisition, culture and delivery. Endogenous mobilization of stem cells offers a non‐invasive alternative.
Blunn, G, Coathup, M, Meeson, R L, Sanghani-Keri, A   +3 more
core   +3 more sources

Bone Augmentation of Atrophic Alveolar Ridges Using a Synthetic Bone Substitute With Mesenchymal Stem Cells: A Randomized, Controlled Clinical Trial

Clinical Oral Implants Research, Volume 36, Issue 11, Page 1498-1514, November 2025.
ABSTRACT Objectives To assess the efficacy and safety of a cell‐based therapy for 3D bone augmentation of severe alveolar bone defects prior to dental implant placement. Materials and Methods A Phase 2 randomized controlled clinical trial evaluated the safety and efficacy of a cell therapy using expanded autologous iliac crest‐derived mesenchymal cells
Mariano Sanz, Cecilie Gjerde, Bjørn Tore Gjertsen, Alberto Ortiz‐Vigón, Nerea Sanchez, Alain Hoornaert, Jordi Caballe‐Serrano, Maria Giralt‐Hernando, Frederick Gaultier, Nicoleta Reinald, Else Marie Pinholt, Markus Rojewski, Helen Rouard, Nathalie Chevallier, Samih Mohamed‐Ahmed, Xieqi Shi, Tie‐Jun Shi, Hubert Schrezenmeier, Pierre Layrolle, Kamal Mustafa   +19 more
wiley   +1 more source

Distraction Osteogenesis for Brachymetatarsia by Using Internal Device

Plastic and Reconstructive Surgery, Global Open, 2017
Summary:. Congenital brachymetatarsia most commonly involves the fourth ray and may be combined with metacarpal shortening. Now, many reports demonstrated the usefulness of distraction osteogenesis for lengthening of the metatarsals by using an external ...
Reina Kitabata, MD, Yoshiaki Sakamoto, MD, Tomohisa Nagasao, MD, Kazuo Kishi, MD   +3 more
doaj   +1 more source